ID S5ZFT9_9CREN Unreviewed; 219 AA.
AC S5ZFT9;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Corrinoid methyltransferase {ECO:0000313|EMBL:AGT36023.1};
GN ORFNames=N186_08425 {ECO:0000313|EMBL:AGT36023.1};
OS Thermofilum adornatum.
OC Archaea; Thermoproteota; Thermoprotei; Thermofilales; Thermofilaceae;
OC Thermofilum.
OX NCBI_TaxID=1365176 {ECO:0000313|EMBL:AGT36023.1, ECO:0000313|Proteomes:UP000015543};
RN [1] {ECO:0000313|EMBL:AGT36023.1, ECO:0000313|Proteomes:UP000015543}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1910b {ECO:0000313|Proteomes:UP000015543};
RX PubMed=24029764;
RA Dominova I.N., Kublanov I.V., Podosokorskaya O.A., Derbikova K.S.,
RA Patrushev M.V., Toshchakov S.V.;
RT "Complete Genomic Sequence of 'Thermofilum adornatus' Strain 1910bT, a
RT Hyperthermophilic Anaerobic Organotrophic Crenarchaeon.";
RL Genome Announc. 1:e00726-13(2013).
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DR EMBL; CP006646; AGT36023.1; -; Genomic_DNA.
DR RefSeq; WP_020963330.1; NC_022093.1.
DR AlphaFoldDB; S5ZFT9; -.
DR GeneID; 16574329; -.
DR KEGG; thb:N186_08425; -.
DR PATRIC; fig|1365176.7.peg.1667; -.
DR eggNOG; arCOG02028; Archaea.
DR HOGENOM; CLU_082102_2_0_2; -.
DR OrthoDB; 134276at2157; -.
DR Proteomes; UP000015543; Chromosome.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02070; corrinoid_protein_B12-BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR036594; Meth_synthase_dom.
DR PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR45833:SF1; METHIONINE SYNTHASE; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR SMART; SM01018; B12-binding_2; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF47644; Methionine synthase domain; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51337; B12_BINDING_NTER; 1.
PE 4: Predicted;
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:AGT36023.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000015543};
KW Transferase {ECO:0000313|EMBL:AGT36023.1}.
FT DOMAIN 1..89
FT /note="B12-binding N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51337"
FT DOMAIN 90..219
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
SQ SEQUENCE 219 AA; 23971 MW; EFE9A06ACC3D9382 CRC64;
MSDASEVLYR AIVDGDDRLA SDATQKLLEE GLSPREIISN ILVPAMRRVG ELYEKGEYFI
PELVASAEAF RASMDVLRPH IKGSSDVPVT GVAVFGTVRG DIHELGKNLA AAVFEAEGFQ
VIDLGVDVPP ERFAEAAEKY NADVVGMSAL MTTTMLEQRN VIEELKKRGI REKVIVIAGG
APVTEEWVRE IGADVWGRDA FESVRIVKEM LAKRRGGAR
//
