ID S6AG61_PSERE Unreviewed; 492 AA.
AC S6AG61;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Heavy metal efflux pump membrane fusion protein CusB {ECO:0000313|EMBL:BAN49187.1};
GN Name=cusB {ECO:0000313|EMBL:BAN49187.1};
GN ORFNames=PCA10_34550 {ECO:0000313|EMBL:BAN49187.1};
OS Pseudomonas resinovorans NBRC 106553.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1245471 {ECO:0000313|EMBL:BAN49187.1, ECO:0000313|Proteomes:UP000015503};
RN [1] {ECO:0000313|EMBL:BAN49187.1, ECO:0000313|Proteomes:UP000015503}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 106553 {ECO:0000313|EMBL:BAN49187.1,
RC ECO:0000313|Proteomes:UP000015503};
RX PubMed=23887915; DOI=10.1128/genomeA.00488-13;
RA Shintani M., Hosoyama A., Ohji S., Tsuchikane K., Takarada H., Yamazoe A.,
RA Fujita N., Nojiri H.;
RT "Complete Genome Sequence of the Carbazole Degrader Pseudomonas
RT resinovorans Strain CA10 (NBRC 106553).";
RL Genome Announc. 1:e00488-13(2013).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP013068; BAN49187.1; -; Genomic_DNA.
DR RefSeq; WP_016493332.1; NC_021499.1.
DR AlphaFoldDB; S6AG61; -.
DR STRING; 1245471.PCA10_34550; -.
DR KEGG; pre:PCA10_34550; -.
DR PATRIC; fig|1245471.3.peg.3494; -.
DR eggNOG; COG0845; Bacteria.
DR eggNOG; COG5569; Bacteria.
DR HOGENOM; CLU_018816_13_1_6; -.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000015503; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 6.10.140.730; -; 1.
DR Gene3D; 2.40.50.320; Copper binding periplasmic protein CusF; 1.
DR InterPro; IPR021647; CusF_Ec.
DR InterPro; IPR042230; CusF_sf.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR045800; HMBD.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30097; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR PANTHER; PTHR30097:SF15; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR Pfam; PF11604; CusF_Ec; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR Pfam; PF19335; HMBD; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000015503}.
FT DOMAIN 51..78
FT /note="Heavy metal binding"
FT /evidence="ECO:0000259|Pfam:PF19335"
FT DOMAIN 111..319
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 492 AA; 52519 MW; 4E99E294FBC33684 CRC64;
MSRAAWKLPA LMGLVLLVGA AGGYWFAAQG RPTAVSEVAA PTATDERQPL YWYDPMFPQQ
KFDSPGKSPF MDMQLVPKFA DEANDSSSVR IEPGIQQNLG VRLATVTKGK LEQSLQVSGV
LAFNAREVAL VQARAAGFVE RTYARAPGDL IAAGEPLADL LIPEWAAAQE EFLALRRSGD
PAMSAAARQR LRLLGMPMEL ITQVERGGKA RPVMTLTSPI KGVIRELDVR IGMTLAAGQT
LARINGLENV WLEAAIPESQ AGALQIGQTV EARLPALLGE VIHGALSSVL PESDPQSRTL
RVRIELANPD GRLRPGMSAQ VRLNQPSQAD LLLVPSEAVI RTGKRALVML AEEGGRFRPV
EVQLGQESEG QVAVLDGLAA GQQVVASGQF LIDSEASLRG IEARALGTPT TSIDRPTLHA
AEGSIVEVGA QELTISHGPF KTLGMPGMTM TFPLARPELA RGLKAGDRIS LKVREGDSGL
LIEQLEKLES AP
//
