ID S6AM73_PSERE Unreviewed; 345 AA.
AC S6AM73;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=DNA polymerase III subunit delta {ECO:0000256|ARBA:ARBA00017703};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN Name=holA {ECO:0000313|EMBL:BAN46538.1};
GN ORFNames=PCA10_08060 {ECO:0000313|EMBL:BAN46538.1};
OS Pseudomonas resinovorans NBRC 106553.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1245471 {ECO:0000313|EMBL:BAN46538.1, ECO:0000313|Proteomes:UP000015503};
RN [1] {ECO:0000313|EMBL:BAN46538.1, ECO:0000313|Proteomes:UP000015503}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 106553 {ECO:0000313|EMBL:BAN46538.1,
RC ECO:0000313|Proteomes:UP000015503};
RX PubMed=23887915; DOI=10.1128/genomeA.00488-13;
RA Shintani M., Hosoyama A., Ohji S., Tsuchikane K., Takarada H., Yamazoe A.,
RA Fujita N., Nojiri H.;
RT "Complete Genome Sequence of the Carbazole Degrader Pseudomonas
RT resinovorans Strain CA10 (NBRC 106553).";
RL Genome Announc. 1:e00488-13(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC -!- SIMILARITY: Belongs to the DNA polymerase HolA subunit family.
CC {ECO:0000256|ARBA:ARBA00034754}.
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DR EMBL; AP013068; BAN46538.1; -; Genomic_DNA.
DR RefSeq; WP_016490740.1; NC_021499.1.
DR AlphaFoldDB; S6AM73; -.
DR STRING; 1245471.PCA10_08060; -.
DR KEGG; pre:PCA10_08060; -.
DR PATRIC; fig|1245471.3.peg.811; -.
DR eggNOG; COG1466; Bacteria.
DR HOGENOM; CLU_044694_0_0_6; -.
DR OrthoDB; 9770982at2; -.
DR Proteomes; UP000015503; Chromosome.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd18138; HLD_clamp_pol_III_delta; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR032780; DNA_pol3_delt_C.
DR InterPro; IPR010372; DNA_pol3_delta_N.
DR InterPro; IPR005790; DNA_polIII_delta.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01128; holA; 1.
DR PANTHER; PTHR34388; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR PANTHER; PTHR34388:SF1; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR Pfam; PF14840; DNA_pol3_delt_C; 1.
DR Pfam; PF06144; DNA_pol3_delta; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000313|EMBL:BAN46538.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000015503};
KW Transferase {ECO:0000313|EMBL:BAN46538.1}.
FT DOMAIN 20..191
FT /note="DNA polymerase III delta N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06144"
FT DOMAIN 216..340
FT /note="DNA polymerase III subunit delta C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14840"
SQ SEQUENCE 345 AA; 37440 MW; C95C464D1849EE70 CRC64;
MKLNPAQLGK HLQGPLAPVY VVSGDEPLLC QEACDAIRAN VRGRDFSERQ VFNAEANFDW
GLLLEAGASL SLFAEKRLIE VRLPSGKPGD KGAAALLEYL SRPPEDTVLL LSLPKLDGST
QKTKWAKALI DGQGAQFIQV WPVEAHNLPQ WIRQRLSQAG LAANQEAVDL IAARVEGNLL
AAAQEIEKLK LLAEGGQVDA ATVQAAVADS ARFDVFGLID AALNGEPAHT LRTLEGLRGE
GVEPPVILWA LARELRLLAS LAQQYSQGVP LDKAFASARP PVWDKRRPLV TRALQRHPAS
RWNQLLQDAQ RIDAQIKGQA QGDPWNGLAR LALLLAGQRL PLPAE
//
