ID S6FN25_CAEEL Unreviewed; 293 AA.
AC S6FN25;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Ricin B lectin domain-containing protein {ECO:0000313|EMBL:CDG24135.1};
GN Name=gly-10 {ECO:0000313|EMBL:CDG24135.1,
GN ECO:0000313|WormBase:Y45F10D.3c};
GN ORFNames=CELE_Y45F10D.3 {ECO:0000313|EMBL:CDG24135.1}, Y45F10D.3
GN {ECO:0000313|WormBase:Y45F10D.3c};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CDG24135.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CDG24135.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CDG24135.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX284604; CDG24135.1; -; Genomic_DNA.
DR RefSeq; NP_001293853.1; NM_001306924.1.
DR AlphaFoldDB; S6FN25; -.
DR SMR; S6FN25; -.
DR PeptideAtlas; S6FN25; -.
DR EnsemblMetazoa; Y45F10D.3c.1; Y45F10D.3c.1; WBGene00001635.
DR GeneID; 178343; -.
DR AGR; WB:WBGene00001635; -.
DR WormBase; Y45F10D.3c; CE48494; WBGene00001635; gly-10.
DR GeneTree; ENSGT00940000166027; -.
DR HOGENOM; CLU_013477_0_1_1; -.
DR OrthoDB; 202750at2759; -.
DR Proteomes; UP000001940; Chromosome IV.
DR Bgee; WBGene00001635; Expressed in germ line (C elegans) and 4 other cell types or tissues.
DR ExpressionAtlas; S6FN25; baseline and differential.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR027791; Galactosyl_T_C.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR11675; N-ACETYLGALACTOSAMINYLTRANSFERASE; 1.
DR PANTHER; PTHR11675:SF134; N-ACETYLGALACTOSAMINYLTRANSFERASE 4-RELATED; 1.
DR Pfam; PF02709; Glyco_transf_7C; 1.
DR Pfam; PF00652; Ricin_B_lectin; 1.
DR SMART; SM00458; RICIN; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 1: Evidence at protein level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Lectin {ECO:0000256|ARBA:ARBA00022734};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Proteomics identification {ECO:0007829|EPD:S6FN25,
KW ECO:0007829|PeptideAtlas:S6FN25};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 146..274
FT /note="Ricin B lectin"
FT /evidence="ECO:0000259|SMART:SM00458"
SQ SEQUENCE 293 AA; 33822 MW; B8F48F347A110CD5 CRC64;
MAGGYFAISA KWFWELGGYD EGLDIWGGEQ YELSFKVWQC HGRMVDAPCS RVAHIYRCKY
APFKNAGMGD FVSRNYKRVA EVWMDDYKET LYKHRPGVGN ADAGDLKLMK GIREKLQCKS
FDWFMKEIAF DQDKYYPAVE PKASAEGEIR NVGTNFCIDT QFKEQNQRFG LRKCTSDDKD
GGGEQDLRLT RWHDIRPKGR KICFDCSTSV DKAPVILFDC HSMKGNQLFK YRVAQKQIYH
PISGQCLTAD ENGKGFLHMK KCDSSSDLQK WAWQTVDNEL LETRQANEAK EQE
//
