ID   S6GQE7_9GAMM            Unreviewed;       446 AA.
AC   S6GQE7;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=Cytosine/purines uracil thiamine allantoin permease {ECO:0000313|EMBL:EPJ49320.1};
GN   ORFNames=OFPII_01580 {ECO:0000313|EMBL:EPJ49320.1};
OS   Osedax symbiont Rs1.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Oceanospirillaceae.
OX   NCBI_TaxID=1330036 {ECO:0000313|EMBL:EPJ49320.1, ECO:0000313|Proteomes:UP000014822};
RN   [1] {ECO:0000313|EMBL:EPJ49320.1, ECO:0000313|Proteomes:UP000014822}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rs1 {ECO:0000313|Proteomes:UP000014822};
RA   Yi H., Goffredi S.;
RT   "Comparative genomics of two novel heterotrophic symbionts of deep-sea
RT   Osedax worms: functional variation and environmental selection.";
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC       {ECO:0000256|ARBA:ARBA00008974, ECO:0000256|PIRNR:PIRNR002744}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPJ49320.1}.
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DR   EMBL; ASZJ01000011; EPJ49320.1; -; Genomic_DNA.
DR   AlphaFoldDB; S6GQE7; -.
DR   PATRIC; fig|1330036.3.peg.146; -.
DR   Proteomes; UP000014822; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015209; F:cytosine transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR   InterPro; IPR030191; CodB.
DR   InterPro; IPR001248; Pur-cyt_permease.
DR   InterPro; IPR026030; Pur-cyt_permease_Fcy2/21/22.
DR   PANTHER; PTHR30569:SF0; CYTOSINE PERMEASE; 1.
DR   PANTHER; PTHR30569; CYTOSINE TRANSPORTER CODB; 1.
DR   Pfam; PF02133; Transp_cyt_pur; 1.
DR   PIRSF; PIRSF002744; Pur-cyt_permease; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002744};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014822};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|PIRNR:PIRNR002744}.
FT   TRANSMEM        21..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        45..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        89..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        130..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        194..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        232..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        275..298
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        310..328
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        340..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        382..404
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        410..429
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   446 AA;  48850 MW;  FAF52BEFA9C0BDE4 CRC64;
     MIEKLNPVHM NERTMGFKET FGLWIAANVV ITTVLTGMLF AEQITLYQCL FAVVVGSLVG
     SIPLALTAKM GFRTGLPTMA VARGAFGQRG AILPAIVNVF MLIAWSWIQA YLAGVSLNYA
     VNYMFGYDNV NLFVIFTELV VILITINGHR LIETLEKTIA NVMLVLSVVI FAVMFTHYDV
     HNIITMKVAE NPDISTIVAF DIVIATAFSW MSSVCDYNRH CKTERSSVIG TYSGYVLASV
     IAMMLGFIVA AFSITSGAEG TYDPTVLLVD AGLGFYGFVA AVIVFLSVVS TNVMGLYSAT
     YSMMSIKENL NFQVIVVILG IAVALGALMK ETLMASFFDF ILLISTLFIP IFAIILTDFF
     VLKGGEYDNE DICSNEKKLY HYFHGFNLLS IAAYVSGAGF GYYFTYVNPL AVGSAIPTFI
     ISALIYLLLM RVSAKDTNKV ELQNNG
//