ID S7MUQ1_MYOBR Unreviewed; 673 AA.
AC S7MUQ1;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=DNA polymerase iota {ECO:0000313|EMBL:EPQ07165.1};
GN ORFNames=D623_10017285 {ECO:0000313|EMBL:EPQ07165.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ07165.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
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DR EMBL; KE162126; EPQ07165.1; -; Genomic_DNA.
DR AlphaFoldDB; S7MUQ1; -.
DR eggNOG; KOG2095; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0071897; P:DNA biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 6.10.250.1630; -; 2.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR024728; PolY_HhH_motif.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR46404; DNA POLYMERASE IOTA; 1.
DR PANTHER; PTHR46404:SF1; DNA POLYMERASE IOTA; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF11798; IMS_HHH; 1.
DR PIRSF; PIRSF036603; DPol_eta; 2.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 4: Predicted;
KW DNA synthesis {ECO:0000256|ARBA:ARBA00022634};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978}.
FT DOMAIN 1..200
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT REGION 245..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 421..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 602..636
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..263
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 506..554
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 555..569
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 607..632
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 673 AA; 75385 MW; 857A17F654B2DC58 CRC64;
MISNPELKGK PLGVQQKYLV VTCNYEAREL GVKKLMNVRD AKEKCPQLVL VNGEDLTRYR
EISYKVTELL EEFSPVVERL GFDENFVDLT EMVEKRLQQL PSDDLSALTV SGHVYNNQSI
NLHDVLHIKL LVGSQIAAEM REAMYNQLGL TGCAGVASNK LLAKLVSGIF KPNQQTVLLP
ESSQDLIHSL KHIKEMPGIG YKTAKRLEAL GISSVHDLQT FSSKILEKEL GISIAQRIQK
LSFGEDNSPV TPSGPPQSFS EEDSLKKCSS EVEAKSKIQE LLANLLKRVC QDGRKPHTIR
LIIRRYSSEK HCSRESRQCS IPSHIIQKLG TGSYDVMTPM VDILMKLFRS MVNVKMPFHL
TLLSVCFCNL KSLNTTKKGT IDYYLTPSLS TTSCSGKRSF KMKDTQMEDF SKDKKTNWDF
LPTGRIESPR TGESPLNTIS FSKDQNSDDF PLRSLPEGID EEVFKQLPVD IQEEILSGKS
REKVQGKGSL SSPLQASRGI LSFFSTKQMQ DSPLNPRDNL SNSKQMSSSS PCEPGTSGLN
NSSSYLSSQK DSSHYLDSSL KDERMSQGPK KSQGFHFSNT NPTVSVFHSF PNLQSEQLFS
KNRTTDSHKQ PTAEASDHEG LAENREQDST AEKITFPSDV DPKVFYELPE EVQKELLADW
KRRAGSDVHN VHK
//
