ID S7MY50_MYOBR Unreviewed; 633 AA.
AC S7MY50;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 22-FEB-2023, entry version 35.
DE SubName: Full=Keratin, type II cytoskeletal 78 {ECO:0000313|EMBL:EPQ09581.1};
GN ORFNames=D623_10023018 {ECO:0000313|EMBL:EPQ09581.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ09581.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; KE162789; EPQ09581.1; -; Genomic_DNA.
DR AlphaFoldDB; S7MY50; -.
DR eggNOG; ENOG502SPJX; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 2.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR032444; Keratin_2_head.
DR InterPro; IPR003054; Keratin_II.
DR PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45616:SF18; KERATIN, TYPE II CYTOSKELETAL 78; 1.
DR Pfam; PF00038; Filament; 2.
DR Pfam; PF16208; Keratin_2_head; 1.
DR PRINTS; PR01276; TYPE2KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 3.
DR PROSITE; PS00226; IF_ROD_1; 2.
DR PROSITE; PS51842; IF_ROD_2; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685}; Keratin {ECO:0000256|ARBA:ARBA00022744};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978}.
FT DOMAIN 105..418
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT DOMAIN 473..547
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 167..201
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 316..396
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 466..525
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 633 AA; 69777 MW; 0C1434EF4C5C2126 CRC64;
MSLSPSGAQR GFSARSACSA GSRGRSRGSF SSRSLNSFGG CRGGSRGVAW GSGGRPGVRF
GVGSGGPGLS LCPPGGIQEV TINQDLLTPL KIEIDPQFQV VRTQETQEIK TLNNQFASFI
DKVRFLEQQN KVLETKWHLL QQLGVSDSPR GLESFFEDYL GRLRKWLEEL QRQRGTLDAE
LKSCQDQEEE YKAKYEQEAH KRATVENDFV VLKKDVDEVF LSKMELEGKL ESLREHTCFL
RRLYEEELGQ LQTQAGDMSV VLSMDNNRCL DFSDIIAEVR ARYEEITQTS KAEAETLYQT
KYQELQASAQ LHGDSMKEIK VQISQLQQAI QRLQRQIEDL KKQNANLEAA IAHAEQRGEL
ALKDAQAKVT ELEAALRTAK QDMARLLRQY QELMSTKLAL DVEIATYRRL LESEECRMSG
EWNSQVTICE YQGSFREGSP WGAEDPTVTL VYFLQPWGEA VQSCLEELVD SENANLEAAI
AHAEQRGELA LKDAQAKVTE LEAALRTAKQ DMARLLRQYQ ELMSTKLALD VEIATYRRLL
ESEECRMSGE WNSQVTISVG GGSAILSGGT CGLGGGSSCS SVVTGGSNII LGSGQGPVMG
SCSVSSSGSG SGSSGRTILK KTVESSLKTS ITY
//
