ID S7N5L3_MYOBR Unreviewed; 892 AA.
AC S7N5L3;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=General transcription factor 3C polypeptide 3 {ECO:0000313|EMBL:EPQ12281.1};
GN ORFNames=D623_10019953 {ECO:0000313|EMBL:EPQ12281.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ12281.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
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DR EMBL; KE163481; EPQ12281.1; -; Genomic_DNA.
DR AlphaFoldDB; S7N5L3; -.
DR eggNOG; KOG2076; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0006383; P:transcription by RNA polymerase III; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR031699; DUF4720.
DR InterPro; IPR039340; Tfc4/TFIIIC-102/Sfc4.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR23082:SF0; GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 3; 1.
DR PANTHER; PTHR23082; TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 3-RELATED; 1.
DR Pfam; PF15846; DUF4720; 1.
DR Pfam; PF13181; TPR_8; 2.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Signal {ECO:0000256|SAM:SignalP};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..892
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004554689"
FT REPEAT 223..256
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 817..850
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 24..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..121
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 892 AA; 101561 MW; 6BFBC30015461BF5 CRC64;
MPKAFLLLSA ALVLLGPVHG ATLRNQDTWK PLSNPRNRDL ALQGKGKPSA EENPNDAEVP
SSSGTDSAKA QDNDANEGET SDGVSKSVHK VFAFMLGENE DEEEEEEEEE EEEEEEETPE
QPTAGDVFVL EMVLNRETKK MMKEKRPRSK LPRALRGLMG EANIRFARGE HEEAILMCME
IIRQAPLAYE PFSTLAMIYE DQGDMEKSLQ FELIAAHLNP SDTEEWVRLA EMSLEQDNIK
QAIFCYTKAL KYEPTNVRYL WERSSLYEQM GDHKMAMDGY RRILNLLSPS DGDRFMQLAR
DMAKSYYEAN DVTSAINVIQ EAFSKHQGLV SMEDVNIGAE LYISNKQYDK ALEVIMDFSG
IMLEKRATEE GTSEENTAGE NVTCTIPEGV PIDITVKLMV CLVHLNILEP LNPLLTTLVE
QNPEDMGDLY LDVAEAFLDV GEYSSALPLL SALVCSERYN LAVVWLRHAE CLKALGYMER
AAESYGKVVE LAPLHLDARI SLSTLQQQLG RPERALEALE PMYDPDTLAQ DANAAQQELK
LLLHRSTLLF SQGKMYGYMD TLLTMLAMLL KIAMNKAQVC LISSSKSGER HLYLIKVSRD
KISDNNDQET ANCDTKAIFA VLTSVMTKEE WWNLLLKAIF SLCELSRFQE AELLVDSALE
YCSFYDDKQK RKELEYFGLS AAILDKNFRK AYNYIRIMVM ENVSRPHLWN MFNQVTMHSQ
EVRHHRFCLR LMLKHPENHA LCVLNGHNAF VSGSFKHALG QYVQAFRTHP HDPLYSICIG
LTFIHMASQK YVLKRHALIV QGFSFLNRYL SLRGPCQESF YNMGRGFHQL GLSHLAIHYY
HRALELPPMV VEGIEVDQVD LRRDIAYNLS LIYQNSGNIR MAQRLLYTYC VI
//
