ID S7NBQ2_MYOBR Unreviewed; 478 AA.
AC S7NBQ2;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=WD repeat and SOCS box-containing protein 1 {ECO:0000256|ARBA:ARBA00040055};
GN ORFNames=D623_10019603 {ECO:0000313|EMBL:EPQ14779.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ14779.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; KE164055; EPQ14779.1; -; Genomic_DNA.
DR AlphaFoldDB; S7NBQ2; -.
DR eggNOG; KOG0266; Eukaryota.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03746; SOCS_WSB1_SWIP1; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15622:SF12; WD REPEAT AND SOCS BOX-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR15622; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00253; SOCS; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50225; SOCS; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 193..222
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 223..265
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 267..308
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 309..350
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 371..405
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 415..435
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 434..478
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
FT REGION 1..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 478 AA; 53142 MW; 1DA6CE89BF0A5E4E CRC64;
MSERRGSSGA HRSFKEERDR SAAISQAKAV LQKWPGVKEG SGSGEDDSEL SFGRTGAGRG
PRRGGVAAGK PRSRTIGELL ALAAPFDKKC GRENWTVAFA PDGSYFAWSQ GYCTVKLVPW
SQCLTNFLLH GTKNITNSNS LRLSRQNSDG AQKNKPREHI IDCGDIVWSL AFGSSVPEKQ
SRCVNIEWHR FKFGQDQLLL ATGLSNGRIK IWDVYTGKLL LNLVDHTEVV RDLTFAPDGS
LILVSASRDK TLRVWDLKDD GNMMKVLRAH QNWVYSCAFS PDSSMLCSVG ASKAVFLWDM
DKYTMIRKLE GHHHDVVACD FSPDGALLAT ASYDTRVYVW DPHTGDILME FGHLFPPPTP
IFAGGANDRW VRSVSFSHDG LHIASLADDK MVRFWRIDED YPVQVAPLSN GLCCAFSTDG
SVLAAGTHDG SVYFWATPRQ IPSLQHLCRM SIRRVMPTQE VQKLPIPSKV LEFLSYRI
//
