ID S7NJ25_MYOBR Unreviewed; 1176 AA.
AC S7NJ25;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Neural cell adhesion molecule L1-like protein {ECO:0000313|EMBL:EPQ17449.1};
DE Flags: Fragment;
GN ORFNames=D623_10019501 {ECO:0000313|EMBL:EPQ17449.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ17449.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily.
CC L1/neurofascin/NgCAM family. {ECO:0000256|ARBA:ARBA00008588}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KE164359; EPQ17449.1; -; Genomic_DNA.
DR AlphaFoldDB; S7NJ25; -.
DR eggNOG; KOG3513; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 4.
DR CDD; cd00096; Ig; 1.
DR CDD; cd05731; Ig3_L1-CAM_like; 1.
DR CDD; cd04978; Ig4_L1-NrCAM_like; 1.
DR CDD; cd05845; IgI_2_L1-CAM_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR026966; Neurofascin/L1/NrCAM_C.
DR PANTHER; PTHR44170:SF51; NEURAL CELL ADHESION MOLECULE L1-LIKE PROTEIN ISOFORM X1; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF13882; Bravo_FIGEY; 1.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 4.
DR SMART; SM00060; FN3; 4.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50853; FN3; 4.
DR PROSITE; PS50835; IG_LIKE; 6.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1050..1071
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..94
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 98..193
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 205..296
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 301..387
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 393..480
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 485..577
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 584..679
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 684..777
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 782..884
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 888..985
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 663..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1080..1120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1157..1176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1080..1116
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1160..1176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EPQ17449.1"
SQ SEQUENCE 1176 AA; 129785 MW; CEE21FD12C6FF208 CRC64;
VPQVPTITKQ SKEQVAFPFD EYFQIECEAK GNPEPRFTWT KDGKPFDLSD PRVIASNNSG
TFRIPNEGQI AHFQGKYRCF ASNKLGVAMS EEIEFIVPNV PKFPKEKIEP LEVEEGDPLV
LPCNPPTGLP PLHIYWMNIE LEHIQQDERV YMSQEGDLYF ANVEEHDSRN DYCCFAAFPR
LRTIVQKMPM KLTVNSSNSI KQRKPSLLLP PAARGPESAV TVLRGDTLVL ECFAEGLPTP
QVDWEKVGGD LPKGRETKEN YGKMLKIENV SYEDKGNYRC TANNFLGVAT HDFHVTVEEP
PRWTKKPQSG VYSTGSSGIL LCEAEGEPEP VIRWRVNGIP IEENPFAGDV VSPGEVSFTD
LQPNHTAVYQ CEASNAHGTI LANANVDVVD VRPLIETEDE ESYAAVAGSS AFLRCEFFAS
PQAMVSWQKV DAARPLEGPR YHVHANGTLQ VREATVEDAG AYSCWVENAQ GKTAVTASLD
IRNATKLHVS PRDPRVPRSH TLELHCESEC DPHLKPSLRL TWSKGGAAFE TNGTEDGRIL
IDGAHLTISN LTLEDQGVYT CSAHTALDST ANETRVTVID VPDPPENLRL SERQNRSVRL
TWDAGDSHNS NISGYVVEFE GNREEPGRWE TLADVPGEET TVLLPLAPYV RYQFRVIAAN
EVGRSRPSRP SEHHETPPAA PDKNPQNIRV QASQPKEMVI KWEPLKSMDQ NGPGLEYRVA
WKPMGAPVEW EEETVREHSL RVMTPAVYAP YEVQVQALNH LGAGPQPQSV VLYSGEDYPD
AAPVIHGVDV VNSTLAKVTW SSVPKDRVHG RLKGYQINWW KTKSLADGRS LPKEVSILRF
PGQRSSGMLP ALDAFSEFHL TVLAFNAKGA GPESEPYVFQ TPEGVPEQPT FLKVIKVDKD
TATLAWGPPK KLNGNLTGYL LQYQIINDTD EIGELNDVSI TAPSKPIWRL SNLNATTKYK
FYVRACTSRG CGKPVTEETA TLGRGLGKLP EGVNATEKAH PPEVPEPGAE HAVRLLPKNW
VGNNSIFEDV IEARGREYAG LYDDIATQGW FIGLMGAIAV LTLVLLTVCF VKRNRGGKYS
VKDKEDLHPD PDVQSGKDET FGDYSDSDEK PLKGSLRSLT RDLPATESAD SLVPYGDGDQ
GLFSEDGSFI GAYAGSKEKG SVESNGSSTA TFPLRV
//
