ID S7NSU5_MYOBR Unreviewed; 934 AA.
AC S7NSU5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Cysteine-rich motor neuron 1 protein {ECO:0000313|EMBL:EPQ20166.1};
GN ORFNames=D623_10008967 {ECO:0000313|EMBL:EPQ20166.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ20166.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KE164797; EPQ20166.1; -; Genomic_DNA.
DR AlphaFoldDB; S7NSU5; -.
DR eggNOG; KOG1216; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR Gene3D; 6.20.200.20; -; 5.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 1.
DR InterPro; IPR004094; Antistasin-like.
DR InterPro; IPR045813; CRIM1_C.
DR InterPro; IPR011061; Hirudin/antistatin.
DR InterPro; IPR001007; VWF_dom.
DR PANTHER; PTHR46439; CYSTEINE-RICH MOTOR NEURON 1 PROTEIN; 1.
DR PANTHER; PTHR46439:SF1; CYSTEINE-RICH MOTOR NEURON 1 PROTEIN; 1.
DR Pfam; PF02822; Antistasin; 4.
DR Pfam; PF19442; CRIM1_C; 1.
DR Pfam; PF00093; VWC; 6.
DR SMART; SM00214; VWC; 6.
DR SMART; SM00215; VWC_out; 4.
DR SUPFAM; SSF57603; FnI-like domain; 6.
DR SUPFAM; SSF57262; Leech antihemostatic proteins; 3.
DR PROSITE; PS51252; ANTISTASIN; 4.
DR PROSITE; PS01208; VWFC_1; 3.
DR PROSITE; PS50184; VWFC_2; 6.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 838..858
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 231..288
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 298..354
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 366..395
FT /note="Antistasin-like"
FT /evidence="ECO:0000259|PROSITE:PS51252"
FT DOMAIN 402..429
FT /note="Antistasin-like"
FT /evidence="ECO:0000259|PROSITE:PS51252"
FT DOMAIN 436..461
FT /note="Antistasin-like"
FT /evidence="ECO:0000259|PROSITE:PS51252"
FT DOMAIN 464..489
FT /note="Antistasin-like"
FT /evidence="ECO:0000259|PROSITE:PS51252"
FT DOMAIN 503..560
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 574..632
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 648..706
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 714..771
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
SQ SEQUENCE 934 AA; 103010 MW; ECB49C321D2DDF15 CRC64;
MRRGSAADEN WDDDQLLGFE PCKENLVSGC NIINGKCECV TVRNCNNPFE FPRKDLCLSA
LKRIQEEKPD CSKARCEVQF SPRCPEDSVL IEGYAPPGKC CPLPSRCVCD PAGCLRKVCQ
PGYLNILVSK ASGKPGECCD LYECKPVFSV DCSTVECPSV QQAVCPLDSY ETQVRLTADG
CCTLPTRCEC LSGLCGFPVC EVGSVPRIVS RGDGTPGKCC DVFECVNETK PACVFNNVEY
NDGDMFRLDK CRFCRCQGGV AICFTAQCGE LNCERYYVPE GECCPVCEDP VYPFNNPAGC
YANGQILAHG DRWREDDCTF CQCINGEPHC VATVCGQSCM NPVKVPGECC PVCEEPTYIT
IDPPACGEPP NCTLTEKNCV YGFKLDHNGC RTCQCKSREE LCWGLLRGCT LDCPFGFLTD
AHSCEICRCR PRPKKCRPTT CDKSCPFGYL KNKHGCDICR CRKCPELPCN KTCLLGFQND
SRGCLTCRCR EVPASPTSPA LSGTCLSMDG HHHKNEESWH DGCRECYCHN GREMCALITC
PVPACGSPTI RPGQCCPSCS DDFVEQKPEL SAPSICHAPG GEYFVEGETW NIDSCTQCTC
HSGRVMCETE VCPPLLCQNP SRTQDSCCPQ CTDAPLQPSP SRNDSEPSYC RNEEGAMFLA
AESWKPDVCT SCVCMNSLIS CFSESCPAVS CERPVLRKGQ CCPYCIEDSI AKRVVCHFGG
KAYADEERWD IDSCTHCYCL QGQTLCSTVS CPPLPCVEPI NVEGSCCPIC PEMYVPEPTN
VPIEKVNRRG ETDVQVPRRP TPSENDIVHL RRDVGHLKVD YGDNNRRHPA EDSSLDSIAA
VVVPVVIGLS IIIAFLLINQ KKQWIPLLCW YRTPTKPSSL SNQLVSVDSK KGPRAQGDSA
QRMLRIAEPD ARFSGFYSMQ KQNHLQADKF YQTV
//
