ID S7P5J5_MYOBR Unreviewed; 1786 AA.
AC S7P5J5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Laminin subunit beta-1 {ECO:0000313|EMBL:EPQ02872.1};
GN ORFNames=D623_10009078 {ECO:0000313|EMBL:EPQ02872.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ02872.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KE161280; EPQ02872.1; -; Genomic_DNA.
DR RefSeq; XP_005858528.2; XM_005858466.2.
DR GeneID; 102250973; -.
DR KEGG; myb:102250973; -.
DR CTD; 3912; -.
DR eggNOG; KOG0994; Eukaryota.
DR OrthoDB; 90222at2759; -.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR CDD; cd22300; cc_LAMB1_C; 1.
DR CDD; cd00055; EGF_Lam; 13.
DR CDD; cd00890; Prefoldin; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 9.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 2.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR013015; Laminin_IV_B.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574:SF233; LAMININ SUBUNIT BETA-1; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00053; Laminin_EGF; 13.
DR Pfam; PF21199; LAMININ_IV_B; 1.
DR Pfam; PF00055; Laminin_N; 1.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00181; EGF; 10.
DR SMART; SM00180; EGF_Lam; 13.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 13.
DR SUPFAM; SSF46579; Prefoldin; 1.
DR PROSITE; PS01248; EGF_LAM_1; 5.
DR PROSITE; PS50027; EGF_LAM_2; 11.
DR PROSITE; PS51116; LAMININ_IVB; 1.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..1786
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004543527"
FT DOMAIN 31..270
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 271..334
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 398..457
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 458..509
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 549..767
FT /note="Laminin IV type B"
FT /evidence="ECO:0000259|PROSITE:PS51116"
FT DOMAIN 773..820
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 821..866
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 867..916
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 917..975
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 976..1027
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1028..1083
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1084..1131
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1132..1178
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT COILED 1250..1312
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1353..1380
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1458..1513
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1561..1668
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1698..1774
FT /evidence="ECO:0000256|SAM:Coils"
FT DISULFID 300..309
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 428..437
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 481..490
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 493..507
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 773..785
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 775..792
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 794..803
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 821..833
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 823..840
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 842..851
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 886..895
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 946..955
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1000..1009
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1028..1040
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1056..1065
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1084..1096
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1086..1103
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1105..1114
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1132..1144
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1134..1151
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1153..1162
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ SEQUENCE 1786 AA; 197618 MW; 3D88EAB7CEA76472 CRC64;
MGLLQVLAFC VLAVFGIRVR AQEPEFSYGC AEGSCYPATG DLLIGRAQRL SVTSTCGLHQ
PEPYCIVSHL QEDKKCFICN SQDPYHETLN PDSHLIENVV TTFAPNRLKI WWQSENGVEN
VTIQLDLEAE FHFTHLIMTF KTFRPAAMLI ERSSDFGKTW GVYRYFAYDC ESSFPGVSTG
PMKNVDDIIC DSRYSDIEPS TEGEVIFRAL DPAFKIDDPY SPRIQNLLKI TNLRIKFVKL
HTLGDNLLDS RMEIREKYYY AVYDMVVRGN CFCYGHASEC APVDGVDEEV EGMVHGHCMC
RHNTKGLNCE LCMDFYHDLP WRPAEGRNSH ACKKCNCNEH SSSCHFDMAV FLATGNISGG
VCDDCQHNTM GRSCEQCKPF YYQHPERDVR DPNFCEQCTC DPAGSQNEGI CDSYTDFSAG
LIAGQCRCKL YVEGEHCDIC KEGFYGLSAE DPFGCKSCAC NPLGTIPGAN PCDSESGYCY
CKRLVTGQHC DQCVPEHWGL SNDLDGCRPC DCDFGGALNS SCSAESGQCM CRPHMIGRQC
NEVESGYYFT TLDHYIYEAE EANFGPEVTI VERQYVQDRI PSWTGAGFVQ VPEGAYLEFV
IDNIPYSMEY EILIRYEPQL PDQWEKAVIT VQRPGKIPTS SRCGNTVPDD DNQVVSLSPG
SRYVVLPRPV CFEKGVNYTV RLELPQYTTS DSGVESPYTF IDSLVLMPFC QSLDIFTVGG
SGDGAVTNGA WEIFQRYRCL ENSRSVVKTP MTDVCRNIIF SISALIHQTG LACECDPQGS
LSSVCDPNGG QCQCRPNVVG RTCDRCAPGT FGFGPSGCKP CDCHLQGSVS AFCDPVTGQC
HCFQGVYARQ CDRCLPGYWG FPSCQPCHCN GHADDCDSVT GECLSCQDYT AGHHCERCLA
GYYGDPIIGS GDHCRPCPCP DGPDSGRQFA SSCYQDPVTL QLACVCNPGY IGSRCEDCAP
GFFGNPSEVG GACRPCHCHH NIDTTDPDAC DKETGRCLRC LYHTEGEHCQ RCRFGYYGDA
LQQDCRKCVC NSLGTVQDYC NSSDCQCDKT TGQCPCLPNV VGQNCDRCAP NTWQLASGTG
CDPCNCDAAH SFGPSCNEFT GQCQCMPGFG GRTCSECQEL FWGDPNVECR ACDCDPRGIE
TPQCDQSTGQ CVCVEGVEGP RCDKCTRGYS GVFPDCTPCH QCFAVWDVII AELTNRTQKF
LEKAKALKIS GVIGPYQETV DSVEKKVNEI RDILAQNPAA EPLKNIGSLF EEAEKLTKDV
TEKMAQVEVK LSDTDSQRNS TAQELDSLQA EAESLDTTVK ELAEQLEFIK NSDIRGALDS
ITKYFQMSLE AEKRVNASTT DPNSTVEQSE LTRESVEHLM MEQESQFREK QEEQARLLDE
LAGKLQSLDL SAAAEMTCGT PPGASCSETE CGGPNCRTDE GQKKCGGPGC GGLVTAAHSA
WQKAMDFDRD ILSALAEVEQ LSKMVSEAKI RADEAKQNAQ DVLLKTNATK EKVDQSNEDL
RNLIKQIRDF LMQDGADLDS IEAVANEVLK MEMPSTPEQL QNLTEDIRER VESLSQVEVI
LQQSAADVAR AEMLLEEAKR ASKSATSVKV TADMVKEALE EAEKAQIAAE KAIKQADEDI
QGTQNLLTSI ESETAASEET LFNASQRISE LERNMEELKR KAAQNSGEAE YIEKVVYAVK
QSAEDVKKIL DGELDEKYKK VENLIAKKTE ESADARRKAE MLQNEAKTLL AQANSKLQLL
KDLERKYEDN QKYLEDKAQE LERLEGEVRS LLKDISQKVT IYSTCL
//
