ID S7P9X7_MYOBR Unreviewed; 495 AA.
AC S7P9X7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=RUN and FYVE domain-containing protein 1 {ECO:0000313|EMBL:EPQ06943.1};
GN ORFNames=D623_10016182 {ECO:0000313|EMBL:EPQ06943.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ06943.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
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DR EMBL; KE162077; EPQ06943.1; -; Genomic_DNA.
DR AlphaFoldDB; S7P9X7; -.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd17694; RUN_RUFY1; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.58.900; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047335; RUFY1-3.
DR InterPro; IPR004012; Run_dom.
DR InterPro; IPR037213; Run_dom_sf.
DR InterPro; IPR047330; RUN_RUFY1.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45956:SF4; RUN AND FYVE DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR45956; RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF02759; RUN; 1.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00593; RUN; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF140741; RUN domain-like; 1.
DR PROSITE; PS50826; RUN; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 30..162
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT DOMAIN 447..486
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT COILED 213..424
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 495 AA; 56547 MW; D1BC7B7881E62934 CRC64;
MEERANLMHM MKLSIKVLLQ SALSLGRSLD ADHAPLQQFF VVMEHCLKHG LKVKKSFIGQ
NKSFFGPLEL VEKLCPEASD IATSVRNLPE LKTAVGRGRA WLYLALMQKK LADYLKVLID
NKHLLSEFYE PEALMMEEEG MVIVGLLVGL NVLDANLCLK GEDLDSQVGV IDFSLYLKDM
QDLDGGKEHE RITDVLDQKN YVEELNRHLS CTVGDLQTKI DGLEKTNSKL QEELSAATDR
IFSLQEEQQQ LREQNELIRE RSEKSVEELE KELELQIGMK TEMEIAMKLL EKDTHEKQDT
LVALRQQLEE VKAINLQMFH KVQDTESSLQ QKDEAIASFE EKINQVMSSM KQMEESSSLE
KELKSEKEQR QALQRELQCE KDTSSLLRAE LQQVDGLKRE LRALQDEKAE LQKVCDEQEQ
ALQEMGLHLS QSKLKMEDIK EVNKALKHHC RNCGHIFCNT CSSNELALPS YPKPVRVCDS
CHTLLLQRCS SSTGS
//
