ID S7PFT6_MYOBR Unreviewed; 3217 AA.
AC S7PFT6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=IgGFc-binding protein {ECO:0000313|EMBL:EPQ09333.1};
GN ORFNames=D623_10013362 {ECO:0000313|EMBL:EPQ09333.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ09333.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
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DR EMBL; KE162692; EPQ09333.1; -; Genomic_DNA.
DR eggNOG; KOG1216; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR CDD; cd19941; TIL; 6.
DR Gene3D; 2.10.25.10; Laminin; 5.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR HAMAP; MF_00351; RNA_methyltransf_FlpA; 1.
DR InterPro; IPR000692; Fibrillarin.
DR InterPro; IPR020813; Fibrillarin_CS.
DR InterPro; IPR003645; Fol_N.
DR InterPro; IPR035234; IgGFc-bd_N.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036084; Ser_inhib-like_sf.
DR InterPro; IPR002919; TIL_dom.
DR InterPro; IPR025615; TILa_dom.
DR InterPro; IPR014853; VWF/SSPO/ZAN-like_Cys-rich_dom.
DR InterPro; IPR001007; VWF_dom.
DR InterPro; IPR001846; VWF_type-D.
DR PANTHER; PTHR11339; EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED; 1.
DR PANTHER; PTHR11339:SF244; IGGFC-BINDING PROTEIN; 1.
DR Pfam; PF08742; C8; 5.
DR Pfam; PF01269; Fibrillarin; 1.
DR Pfam; PF17517; IgGFc_binding; 1.
DR Pfam; PF01826; TIL; 5.
DR Pfam; PF12714; TILa; 5.
DR Pfam; PF00094; VWD; 7.
DR PRINTS; PR00052; FIBRILLARIN.
DR SMART; SM00832; C8; 6.
DR SMART; SM01206; Fibrillarin; 1.
DR SMART; SM00274; FOLN; 4.
DR SMART; SM00215; VWC_out; 5.
DR SMART; SM00216; VWD; 7.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF57567; Serine protease inhibitors; 5.
DR PROSITE; PS00566; FIBRILLARIN; 1.
DR PROSITE; PS51233; VWFD; 7.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..3217
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004543618"
FT DOMAIN 470..650
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 801..980
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 1189..1368
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 1607..1790
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 2006..2194
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 2295..2466
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 2674..2846
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT REGION 2104..2148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2918..2981
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3217 AA; 343370 MW; C87A04E6C71D337B CRC64;
MGFLWSWWTL WAGATLLWGL TQEASADPSN AEGEEFLTAF LQNYQPGYVK GNLYLLITSL
SDSSASVTIL SQADGTSQNV PVKPGQSVMV NISTKAEMIG SNIFQHAVLV RSDRNISVQA
INTKPNTEDL TLLRPVSTLG TTYFVFTPPS ASAKNVKEFA VVAGAKGASI SVQLKAAVTF
QGNFYPGGSV LTVTLKPYQV AQVQSTADLS GSKVTASSPV VVLSGHSCAQ KHTSCNHVVE
QLLPTSAWGT HYVVPPLASQ TRFDVVYAVA SQPTKLTYNH GNIIGSRGLQ EGDVIEFEVR
PSWPLFLSAD VGIQVLLFGT GGTRDRVTYD PYLVLIPDVE AYCPAYVVKN FPGSKGVALV
VAQTKAADKL TIDGHELGTR LTWATVPGSE FSYAEVDLNS TNMIHMTMAN TSFGLLTFWL
TQSGGYGTAA ACGQTLLSAE KPSCEGVQCP PSQICQVVDG HAKCMPGSVA VCRAQGDPHY
TTFDGRRYDM MGTCSYTMVE LNSEDQTLPA FSVEAKNEHR GSRRVSYVGF VTVHAYSHSV
SLARGEVGFA RIDNQRSRLP ASLAEGSLRV YQSGRRAIVE LDFGLVVSYD WDCQLALSLP
TRFQGQVYGL CGNYNGDATD DFLTPDGEQA PNVVEFANSW KLDDGDFLCE DSCQDNCPSC
TPGQAQHYEG DRLCGMLTKP NGPFAACHDT LSPWPFLKEC VYDLCVLNGD RSSLCRGLSV
YAQACLELGV SIKDWRSPAN CPLSCPANSR YELCGPACPA SCNPTAAPAN CSGRPDTQGC
PAGERCRVQN GLLGCYPDRF GSCQASGDPH YVSFDGRRFD FMGTCTYLLA GSCGQNAALP
AFRVLVENEH RGSQTVSYTR AVRLEARGVK VAVRREHPGQ VLVDGILQYL PFQAADGQVQ
VFRQGQDVVI RTDFGLTVTY DWNARVTAKV PGSYAGALCG LCGNFNGNPD DDLALRGGGQ
ADNALDFGKS WQEETRPGCE ATKPGDCPKL DSLVAQQLQS KKECGILADP KGPFRECHRK
LDPQGAVRDC VYDLCLLPGQ SGPLCDTLAA YAAACQATGA TVHPWRSEKL CPLSCPPHSH
YELCSRGCPL SCGDLPVPGG CGSDCHEGCV CDEGFALNGE SCVPLSSCGC LYQGIYHPPG
QTFYPGPGCD SLCHCQEGGL VSCKPSTCGP HEACQPSGGI LGCVAVGSAT CQASGDPHYT
TFDGRRFDFM GTCVYVLAQT CGTRPGLDQF AVLQENVEWN NRKVSVTRVV TVQVANFTLR
LEQNQWKIKV NGVDMKLPVV LAQGRVRASQ HGSDIVIQTD FGLRVAYDLM YNVRVTVPGN
YYQQLCGLCG NYNGDPKDDF QKPDGSQAGS PNEFGNSWEE AVPGSPCVRP PTCKPGEDCN
PPECGPELQS KYQQEQFCGL LTSPTGPLAA CHKLLDPQGP LFDCVFDLCV GDGSQNILCS
NIHAYVSACQ ALGGHVKPWR NESFCPMKCP SNSHYELCAD TCSLSCSALS AAPQCPDNCA
EGCQCDPGFL SDGQACVPIQ KCGCYHNGVY YEPEQTVLID SCRQQCVCHA GKGLVCQNYS
CEAGHVCQSV AGILSCVKEL CHGVTCRPQE TCQEKGGHGV CVPNYEATCW LWGDPHYHSF
DGWDFDFQGT CNYVLATTSC PGVNSQGLTP FTITTKNENR GNPAVSYVRL VTVTALNINI
SIHKGEVGKV RVNGVLTALP TSVAGGRLSV TQGASKAILA ADFGLRVSYD WNWRVEVTLP
SSYHGAVCGL CGNMDRNPNN DQAFPNRTLA HSIPVWGGSW RAPGWDPLCW DECQGSCPTC
PEDQLEEYRG PGFCGPLAAD AKGPFAACHA HVAPESFFKG CVLDVCLGGG AHDILCQALA
TYAAACQAAG IVIEDWRTQA GCEISCPNNS HYELCGPPCP ASCPSPAPPT IPAPCEGPCA
EGCQCDAGFV LSVDRCVPLD GGCGCWANNT YHEAGSEFWA GTTCSQKCHC GPGGGSLVCK
PARCGLGEVC ALLPSGQYGC RPVSTAECQA WGDPHYITLD GHRFDFQGTC EYLLSAPCHA
PPAGVENFTV TVANEHRGSQ AVSYTRSVTL HIYNHNLTLS ARWPRQLQVR GLWIRQEHMP
SLKLPGRGRS HAQGAHAPSC SLPLTHPGGR RQDSNLSPGR SLPPPTPHAR RAVAAYVAAC
QAAGAQLGDW RRPDFCPFQC PAHSHYELCG DSCPVSCPSL SAPEGCEPAC REGCVCDAGF
VLSGDTCVPV GQCGCLHEGR YYPLGEAFYP GPECERRCEC GPGGQVSCQE GTACQPYEEC
RIKDGVHACH PKGCGHCVVS GGIHYNTLDG RVYDLHGSCS YVLARVCHPQ PGDEDFAIVL
EKNAAGDPQR LVVTVAGQVV GLAHGLQVTV DGEAVALPVA VGHVQVTAEG RNMVLQTAKG
LRLLFDGDAY ILISVPSPFH GRTCGLCGNF NGNWSDDFVL PSGTVAPSVD AFGAAWRAPG
SSQGCGEGFG PQGWPVCSAE ETAPYESIKA CGQLRDPKGA FAACHPVLSP SEYFRQCVFD
LCAHKGNSTF LCRSLAAYTA ACQAANKAVK PWRTDSFCPL KCPAHSHYSI CTHSCQGSCA
ALSGLMGCTS HCFEGCECDD RYLLSQGICV PVQHCGCTHD GRYLPVNSSL LSSDCSERCS
CSSSTGLTCQ AAGCPLGRVC EVEAGSRDCW VPPGLCSLFM GTNLTTFDGA HSTVRIPGIY
ELSSRCPGIQ KTIPWFRVLA DVHSCHDKVE AVGQVHIFFQ DGLVTVTPNK GVWVNGLRVR
VDLPAEVLTS VSVNRNPDGS MLVQQKAGVR VQLGTNGQLT VMVSSDHAGM LCGACGNFDG
DQTNDGHNSQ GNTTVEHWRA PDFSPWRLGS ELSGLRFGES LLVRRCRLRE LSLGGPRLPP
LPPSPWPPTR YLLGAAGDGF SPRGGGFGGR GGFGDRGGRG GGRGGFGGGR GGFGGGRGRG
GGFRGRGRGG GGGGGRGGGF QSGGNRGRGR GGKRGNQSGK NVMVEPHRHE GVFICRGKED
ALVTKNLVPG ESVYGEKRVS ISEGEDKIEY RAWNPFRSKL AAAILGGVDQ IHIKPGAKVL
YLGAASGTTV SHVSDIVGPD GLVYAVEFSH RSGRDLINLA KKRTNIIPVI EDARHPHKYR
MLIAMVDVIF ADVAQPDQTR IVALNAHTFL RNGGHFVISI KANCIDSTAS AEAVFASEVK
KMQQENMKPQ EQLTLEPYER DHAVVVGVYR PPPKVKN
//
