ID S7PHW7_MYOBR Unreviewed; 714 AA.
AC S7PHW7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Actin-binding LIM protein 3 {ECO:0000313|EMBL:EPQ10313.1};
GN ORFNames=D623_10034732 {ECO:0000313|EMBL:EPQ10313.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ10313.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; KE162980; EPQ10313.1; -; Genomic_DNA.
DR AlphaFoldDB; S7PHW7; -.
DR eggNOG; KOG1044; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR CDD; cd09327; LIM1_abLIM; 1.
DR CDD; cd09328; LIM2_abLIM; 1.
DR CDD; cd09329; LIM3_abLIM; 1.
DR CDD; cd09330; LIM4_abLIM; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 4.
DR Gene3D; 1.10.950.10; Villin headpiece domain; 1.
DR InterPro; IPR032402; AbLIM_anchor.
DR InterPro; IPR003128; Villin_headpiece.
DR InterPro; IPR036886; Villin_headpiece_dom_sf.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24213; ACTIN-BINDING LIM PROTEIN; 1.
DR PANTHER; PTHR24213:SF0; ACTIN-BINDING LIM PROTEIN 3; 1.
DR Pfam; PF16182; AbLIM_anchor; 1.
DR Pfam; PF00412; LIM; 4.
DR Pfam; PF02209; VHP; 1.
DR SMART; SM00132; LIM; 4.
DR SMART; SM00153; VHP; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 6.
DR SUPFAM; SSF47050; VHP, Villin headpiece domain; 1.
DR PROSITE; PS51089; HP; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 2.
DR PROSITE; PS50023; LIM_DOMAIN_2; 3.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 62..121
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 122..181
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 190..249
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 646..714
FT /note="HP"
FT /evidence="ECO:0000259|PROSITE:PS51089"
FT REGION 413..466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 482..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 415..436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 484..498
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 714 AA; 80849 MW; 9BB2BE4BE11F559D CRC64;
MAGLSPALRS PDSHPELAPP QLLASVRKEA GTVVGCEFKA PAEPHVPYQQ NPYNPRGSSN
AIQCYRCGDT CKGEVVRVHN NHFHIRCFTC QVCGCGLAQS GFFFKNQEYI CTQDYQQLYG
TRCDSCRDFI TGEVISALGR TYHPKCFVCS LCRKPFPIGD KVTFSGKECV CQTCSQSMTS
SKPIKIRGPS HCAGCKEEIK HGQSLLALDK QWHVSCFKCQ TCSVILTGEY ISKDGVPYCE
SDYHSQFGIK CETCDRYISG RVLEAGGKHY HPTCARCVRC HQMFTEGEEM YLTGSEVWHP
ICKQAARAEK KLKHRRTSET SISPPGSSIG SPNRVICAKV DNEILNYKDL AALPKVKSIY
EVQRPDLISY EPHSRYTSDE MLERCGYGES LGTLSPYSQD IYENLDLRQR RASSPGYIDS
PTYSRQGMSP TFSRSPHHYY RSGPESGRSS PYHSQLDVRS STPTSYQAPK HFHIPAGESN
IYRKPPIYKR HGDLSTATKS KTSEDISQAS KYSPAYSPDP YYASESEYWT YHGSPKVPRA
RRFSSGGEED DFDRSMHKLQ SGIGRLILKE EMKARSSSYA DPWTPPRSST SSREALHTAG
YDMSLNGYPL ISKSASLPAY RRNGLHRTPS ADLFHYDSMN AVNWGMREYK IYPYELLLVT
TRGRNRLPKD VDRTRLERHL SQEEFYQVFG MTISEFDRLA LWKRNELKKQ ARLF
//
