ID S7PQ30_MYOBR Unreviewed; 1718 AA.
AC S7PQ30;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Transcription initiation factor TFIID subunit 1 {ECO:0000313|EMBL:EPQ12948.1};
GN ORFNames=D623_10013114 {ECO:0000313|EMBL:EPQ12948.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ12948.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KE163654; EPQ12948.1; -; Genomic_DNA.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:InterPro.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0004402; F:histone acetyltransferase activity; IEA:InterPro.
DR GO; GO:0001091; F:RNA polymerase II general transcription initiation factor binding; IEA:InterPro.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd05511; Bromo_TFIID; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR004015; SKI-int_prot_SKIP_SNW-dom.
DR InterPro; IPR040240; TAF1.
DR InterPro; IPR022591; TAF1_HAT_dom.
DR InterPro; IPR041670; Znf-CCHC_6.
DR PANTHER; PTHR13900; TRANSCRIPTION INITIATION FACTOR TFIID; 1.
DR PANTHER; PTHR13900:SF0; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF12157; DUF3591; 1.
DR Pfam; PF02731; SKIP_SNW; 1.
DR Pfam; PF15288; zf-CCHC_6; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Initiation factor {ECO:0000313|EMBL:EPQ12948.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein biosynthesis {ECO:0000313|EMBL:EPQ12948.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1149..1219
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 28..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 221..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 673..696
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 813..864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 938..960
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1262..1286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1305..1357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1373..1444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1612..1637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..243
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 255..269
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 850..864
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1330..1344
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1396..1413
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1718 AA; 194387 MW; 39A689A697037F8C CRC64;
MLSPLNDFIK QCAAHGAVAG TENKQKKMAL TSFSPAPTQL PQDQLEAEEK ARSQRSQQTS
LVASRREPPP YGYRQGWIPR LVEDFGDGGA FPEIHVAQYP LDMGRKKKMS NALAIQDDII
WDGEDVKHKG TRPQRASLAG WIPSSTTRNA RAYNVQQGCA ATLDDDKPWY SIFPIDNEEL
AYGRWEDNII WDAQAMPRML EPPVLTLDPN DENLILEIPD EGEEATSNSP SKESKKESSP
KKSRILLGKI GVTKEEPQQN RSQPEVKDPW NLSNDEYYYP KQQRLQGTFG GNGIQHSIPA
VELRQPFFPT HMGSLKLRQF HRPALKKYSF GALSQPGPHS VQPLLKHLRE KAKMREQERQ
ASGGGEMLFM RTSQDLTGKD GDLILAEYSE ENGPLMMQVG MATKIKNYYK RKPGKDPGAP
DCKYGETVYC HTSPFLGSLH PGQLLQAFEN NLFRAPIYLH KMPETDFLII RTRQGYYIRE
LVDIFVVGQQ CPLFEVPGPN SKRANTHIRD FLQVFIYRLF WKSADRPRRI RMEDIKKAFP
SHSESSIRKR LKLCADFKRT GMDSNWWVLK SDFRLPTEEE IRAMVSPEQC CAYYSMRAAE
QRLKDAGYGE KSFFAPEEEN EEDFQMKTDD EVRTAPWNTT RAFIAAMKGK CRLQVTGVAD
PTGCGEGFSY VKIPNKPTQQ KDDKEPQPVK KTVTGTDADL RRLSLKNAKQ LLHKFGMPEE
EIKKLSRWEV IDMVRTMSTE QAHSGEGPMS KFARGSRLSV AEHQERYKEE CQRIFDLQNK
VLSSTEVLST DTDSSSAEDS DFEEMGKAIE SMLQNKKTSS QLSREPEQQE RKELQRMLLA
AGSAAAGNNH RDDDTASVTS RNSSATGRCL KIYRTFRDEE GKEYVRCEMV RNPAVIDAYV
RIRTTKSEEV IRKFAPLDEQ HREEMRKERR RIQEQLRRLK RNQEKKTLKG PPEKKPKKLK
ERPALKLKCG ACGAVGHMRT NRCCPLYYPT SAPPSDPVAM TEGQEEELEK TVIHNDSGGL
IKVEGTKIVL GNQLTESADE VRRKSLVLKF PKQQLPPKKK RRVGTTPTPS REGFREHLEL
IVKNSTSDNG PKHSLTQISQ SKLDFCDEKL REREDKLARL EKAINPLLDD NDPVTFSFIL
DNILTLKMMA DPDSWPFHHP VNKKFVPDCY EVIVSPMDLK TICKNISKHK YQSRKSFPDD
VNLILSNSVK YNGPESQYTK TAQEIVNVCC QTLTDYNEHL TQLEKDICTA KEAALEEAEL
DSLDPMTPGP YAPQPPDLYD TSTSLSMSQD ASVFQDGSDI VCPGYSHYHS RKAGEDDEED
AGSDEEGDNP FSAIQLSESG SDSDVGSGGM IPKQPRMLQE NIRMGMENEE SMMSYEGDGG
AASHGLEDSN ISYGSYEEPD PKSNTQDTSF SSIGRHEVSE EEEDEEEEQC SGPRTSLVAS
RREPPPYGFR QGWIPRLLED FGGGGAFPEI HVAQYPLDMG RKKKMSNVLA IQVDAEGKIE
YDAIARQGQS KDKVIFSKYT DQVPKEVMNA DDPDLQRPDE EAITEITEKT RVALEKSVSQ
KVAAAMPVRA ADKLAPAQYI RYTPSQQGVA FYSGAKQRVF RMVEIQKDPM EPPRFKINKK
IPRGPPSPHA PVMHSPSRKM TVKEQQEWEI PPCISNWKNA KGYAIPLDKC LAADGRGLQT
VHINENFAKL AKTLYTADRK AREAVEMRAQ VERKMAQK
//
