ID S7PU83_MYOBR Unreviewed; 1437 AA.
AC S7PU83;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=Early endosome antigen 1 {ECO:0000313|EMBL:EPQ14438.1};
GN ORFNames=D623_10028741 {ECO:0000313|EMBL:EPQ14438.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ14438.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
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DR EMBL; KE163933; EPQ14438.1; -; Genomic_DNA.
DR eggNOG; ENOG502QWB5; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15730; FYVE_EEA1; 1.
DR Gene3D; 1.20.5.390; L1 transposable element, trimerization domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23164; EARLY ENDOSOME ANTIGEN 1; 1.
DR PANTHER; PTHR23164:SF17; EARLY ENDOSOME ANTIGEN 1; 1.
DR Pfam; PF01363; FYVE; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 67..95
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1378..1436
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 498..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 156..225
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 267..444
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1437 AA; 164559 MW; 77932C1197A228FF CRC64;
MTVTGACLGL VPPLTCSTIP PRPTPAMFHT RPLVTPGRVG SQGSDLDSSA TPINTVDVNN
ESSSEGFICP QCMKSLGSAD ELFKHYQAVH DAGNDSGHGG EANLALKRDD VTLLRQEVQD
LQASLKEEKW YSEELKKELE KFQGLQQQVS KPDGLVADSS AELHSLEQQL EEAQTENFNI
KQMKDLFEQK AAQLATEIAD IKSKYDEERS LREAAEQKAS HLTEELNKEG TIIQDLKTEL
LQRPGIEDVA VLKKELVQVQ TLMDNMTLER ERESEKLKDE CKKLQADYAN SEATISQLRS
ELAKGPQEVA VYVQELQKLQ SSVNELTQKN QNLTEKLLKK ELDYTQLEEN HNDECVSKKN
IQASLHQKDL DCQQLQSRLS ASETTLQRIQ AELGEKGEAT QKLKEELLEV ETKYQHLKAE
FKQLQQQREE KEQHGLQLQS EINQLHSKLL ETERQLGEAH GRLKEQRQLS SEKLMDKEQQ
VADLQLKLSR LEEELKENVT NSTELQHQLE KTKQQHQEQQ ALQQSTTAKL REAQNDLEQV
LRQIGDKDQK IQNLEALLQK SKENTSLLEK EREDLYAKIQ AGEGETAVLN QLQEKNHTLQ
EQVTQLTEKL KNQSESHKQA QEDLHDQVQE QKAHLRAAQD RVLSLETSVN ELNSQLNESK
EKVSQLDIQV KAKTELLLSA EAAKTAQRAD LQNHLDTAQN ALQDKQQELN KITTQLDQVT
TKLQEKQEHC SQLEGHLKEY KEKHLSLEQK TEELEGHIKK LEADTLEVKV SKEQALQDLQ
QQRQLNTDLE FRVTELTKQL EVEKEIVSST KLDLQKKSEA LENIKQMLTK QEEEKTILKK
EIENLSQDAK MQHKELNNKI QTAVAELQKV KMEKETLMAE LSASKEKLSK VSDSLKNSKS
EFEKENQKGK AAILDLEKTC KELKHQFQVQ MESTLKDQNE LKKSLEKEKE TSHQLKLELS
SMQGQVIQAQ DNLKQKEKEE QQLQGNINEL KQLTEQRKKQ IEALQGEVKI AVSQKTELEN
KLQQQLTQAS QELATEKEKM SMLQNTYEKS QENLKQLQSD FYGKESELLA TRQDLKSVEE
KLSLAQEDLI SNRNQIGNQN KLIQELKTAK ATLEQDATKK EQQLKEQSAA LQNIQKEKSL
KEKELASEKS KLAEIEEIKC RQEKEIAKLS EELKSHKQES IKELTNLKDA KQLLIQQKLE
LQGTIDSLKA ILEQEKKNQQ MLKEQVKKEE DELKKEFIEK EAKLHSEIKE KEVGMKKHEE
NEAKLTMQIT ALNENLGTVK KEWQSSQRRV SELEKQTDDL RGEIAVLEAT VQNNQDERRA
LLERCLKGEG EIEKLQNKVL EVQRKLDNTT AAVQELGREN QSLQIKHTQA LNRKWAEDNE
VQNCMACGKS FSVTVRRHHC RHCGNIFCAE CSAKNALTPS SKKPVRVCDA CFNDLQG
//
