ID S7PW09_MYOBR Unreviewed; 1082 AA.
AC S7PW09;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=SH3 and PX domain-containing protein 2A {ECO:0000313|EMBL:EPQ15163.1};
DE Flags: Fragment;
GN ORFNames=D623_10025886 {ECO:0000313|EMBL:EPQ15163.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ15163.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
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DR EMBL; KE164114; EPQ15163.1; -; Genomic_DNA.
DR AlphaFoldDB; S7PW09; -.
DR eggNOG; KOG0905; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd12074; SH3_Tks5_1; 1.
DR CDD; cd12077; SH3_Tks5_2; 1.
DR CDD; cd12079; SH3_Tks5_3; 1.
DR CDD; cd12019; SH3_Tks5_4; 1.
DR CDD; cd12020; SH3_Tks5_5; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 5.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR035450; SH3PXD2A_SH3_1.
DR InterPro; IPR035452; SH3PXD2A_SH3_2.
DR InterPro; IPR035449; SH3PXD2A_SH3_3.
DR InterPro; IPR035453; SH3PXD2A_SH3_4.
DR InterPro; IPR035454; SH3PXD2A_SH3_5.
DR PANTHER; PTHR15706:SF2; BUD EMERGENCE PROTEIN 1; 1.
DR PANTHER; PTHR15706; SH3 MULTIPLE DOMAIN; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF00018; SH3_1; 3.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00326; SH3; 5.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 5.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS50002; SH3; 5.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..78
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT DOMAIN 116..175
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 216..275
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 398..457
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 789..848
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1021..1082
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 364..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 455..791
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 845..912
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 978..1009
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 589..622
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..668
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 711..732
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 748..762
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 859..880
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EPQ15163.1"
SQ SEQUENCE 1082 AA; 118779 MW; 31325F2B6C9DB63F CRC64;
QMQLLDKFPI EGGQKDPKQR IIPFLPGKIL FRRSHIRDVA VRRLKPIDEY CRALVRLPPH
ISQCDEVFQF FEARPEDVNP PKEDYGSSKR KSVWLSSWAE SPKKDVTGAD TSAEPMILEQ
YVVVSNYKKQ ENSELSLQAG EVVDVIEKNE SGWWFVSTSE EQGWVPATYL EAQNGTRDDS
DINTSKSGEV SKRRKAHLRR LDRRWTLGGM VNRQHSREEK YVTVQPYTSQ SKDEIGFEKG
VTVEVIRKNL EGWWYIRYLG KEGWAPASYL KKAKDDLPAR KKNLAGPVEI IGNIMEISNL
LNKKTSGDKE TPPAEGEGPE APIAKKEISL PILCNASNGS ALGIPERTVS KLAQGSPAVA
RIAPQRAQIS SPNLRTRPPP RRESSLGFQL PKPPEPPSVE VEYYTIAEFQ SCISDGISFR
GGQKAEVIDK NSGGWWYVQI GEKEGWAPAS YIDKRKKPNL SRRTSTLTRP KVPPPAPPSK
PKEAEEGPAG TAESQDSPLK LKYEEPEYDI PAFGFDSEPE LSEEPTEDRG SGDKRLAQPH
RPSPASSLQR ARFKVGGSSE DVALEEETIY ENEGFRPCAE DTLSARRSSR DSDSPGGSPL
SLARKNSPKS DSPKSSSLLK LKAEKNAQAE LGKNHSSASF SSSITINTTC SSSSSSSSSL
SKPSSDLKPR SASDAGIRGT PKVGAKKDAD LKAGLTSCAR AKPSVRPKPF LNRAESQSQE
KMDISTLRRQ LRPTGQLRGG LKGSKSEDSE LPPQTASEGP NEGSRRGSAD LITLPAATPP
CPTKKGREGQ ATSYVTCSAY QKVQDSEISF PAGVEVQVLE KLESGWWYVR FGELEGWAPS
HYLVLGENEP PDPSGKEPDA VTAKSKQKEG KSDSLEKIEK RVQALNTVNQ SKRATPPIPS
KPPGGFSKTS GAGVVKMRNG VRQVAVRPQS VFVSPPPKDN NLSCALRRNE SLTATDGLRG
VRRNSSFSTA RSAAAEAKGR LAERAASQGS DSPLLPTQRN GIPVSPVRPK PIEKSQFIHN
NLKDVYVSIA DYEGDEETAG FQEGVSMEVL ERNPNGWWYC QILDGVKPFK GWVPSNYLEK
KN
//
