ID S7PXJ0_MYOBR Unreviewed; 2038 AA.
AC S7PXJ0;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Zonadhesin {ECO:0000313|EMBL:EPQ15703.1};
DE Flags: Fragment;
GN ORFNames=D623_10015180 {ECO:0000313|EMBL:EPQ15703.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ15703.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KE164168; EPQ15703.1; -; Genomic_DNA.
DR eggNOG; KOG1216; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd06263; MAM; 1.
DR CDD; cd19941; TIL; 5.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 6.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000998; MAM_dom.
DR InterPro; IPR036084; Ser_inhib-like_sf.
DR InterPro; IPR002919; TIL_dom.
DR InterPro; IPR025615; TILa_dom.
DR InterPro; IPR014853; VWF/SSPO/ZAN-like_Cys-rich_dom.
DR InterPro; IPR001007; VWF_dom.
DR InterPro; IPR001846; VWF_type-D.
DR PANTHER; PTHR11339; EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED; 1.
DR PANTHER; PTHR11339:SF374; ZONADHESIN; 1.
DR Pfam; PF08742; C8; 4.
DR Pfam; PF01826; TIL; 5.
DR Pfam; PF12714; TILa; 5.
DR Pfam; PF00094; VWD; 4.
DR SMART; SM00832; C8; 4.
DR SMART; SM00181; EGF; 5.
DR SMART; SM00137; MAM; 1.
DR SMART; SM00214; VWC; 5.
DR SMART; SM00215; VWC_out; 4.
DR SMART; SM00216; VWD; 4.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF57567; Serine protease inhibitors; 5.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS50060; MAM_2; 1.
DR PROSITE; PS51233; VWFD; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1981..2000
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..232
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 344..518
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 743..923
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 1131..1310
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 1531..1708
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 1929..1965
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2010..2038
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 1955..1964
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EPQ15703.1"
SQ SEQUENCE 2038 AA; 224354 MW; DBF219D3A47587DE CRC64;
TSRTEKPPDQ KPVAHSSRDN CELKTRTAQT LSPFQGGHPC ALQARQLHKC VKGSPYMTEG
GGNTIITQCD FEDNSKPFCD WTQISTNYGN WIRASGPSIM GSTGPTGGYP NGQGCYLHLD
FGTSHRGWVA RLLSSPIWEQ GPLCVHFAYY MFGLSWGAQL KLLLLTGTNN RHPNLLWKHI
NIQSPSWMPT TVTVPKGHVL PTQLIFEGVR GSPAFLDISL DSVSIRRGSC NRASCPPNAH
HEPCACPASC QNPKPNCELV CKPGCVCNPG FVFSDSHCIN ASSCNCFYNN NYYKPGAEWF
SPNCTERCHC WPGSRVQCQT FQCKENKVCQ QKNGQYGCHT YGSATCFVYG DPHYLTFDGR
HFSFMGKCTY ILAQFCGNST EPFFRVAGKN EEGAQEGMSC LSKVYVMLPE TTITLLRGRR
TLVEGQEVNL PAMPSKGIFL VSSGRFVELQ TAFGLRIRWD GDLQLFISVP STYYGQLCGF
CGNYDGDSSN DNKMPDGRLA QDEEELGISW QTIEDIEEDT YASKLCRFCG SHDSDSSTRS
NNYQIPEGML GQHEELGNSW PAEDNMEKKT CLPHLMASFF FNNCMFDMCK YQGLQQMLCV
HMAALTEACQ DAGYMVKPWR GPRFCSLDCP PNSKYTICAK QCPETCHSTF SGMSCQDRCV
EGCECNPGFV LSGLQCIPRS QCGCLDSLGH YIMVGQHWFA PDCRQLCICE GSSKVRCVLW
KCEAQEVCSQ QDGVYGCHAT GTATCTVSGD PHYLTFDGAL HHFMGTCSYT LAQLCWPRSF
DNYFVVSATN EFQGGNAEVS HVTAVHIQVF KLKISLIKGY KVVLNGRRVT LPVWPAQGRV
GIRHSGSFIV LYTDLGLQVR YDGNHLVKVT VPSTYAGRLC GLCGNYNSNS SDDNLKPDGK
PADNSIELGV AWKSNEYSES GCFSAGGKPP RCQENEVADT WNKNCNVLIN PQGPFSQCHK
VVPPESSFAS CVHGQCGTKG DALTLCRSLQ AYASQCAQAG QPPVWRNSTF CPLKCPSGSS
YSPCANPCPA TCRTLNTPKD CPAALPCAEG CECQKGHVLS GASCVPFNEC GCTDPRGSYY
PLGESWYTDT TCSRLCSCST HNISCLDTSC NPGQLCWALH GLIRCRSSGM GVCRIEDKSY
YVSFDGHYHA IRSTCAYVLV KTCHFTTDLP FFKISGENEE REGQSPAFYL RQLNISIFDS
LITLQKDHHV LINGKQVTLP SNNRVRGVRI SASGTYTVLS LYIGMEVKFD GNGFLEIEIP
RAYYGKVCGI CGNFNDEEED EIMMPNDELA QNDIDFVHSW QDKEANPNCQ DDQIDEQMKT
KAGYQETQSA NCKPSHLMRA MKHCKVAFQT PAWTKCAAQV ALTPFLLDCM HNLCELRGLS
HALCDSLQAF GAACQAQGLK PPIWRNSSFC PLECPTHSTY TSCVPSCSLS CWDLEGQCDD
TNVPSTCEEG CICQPGYVLS EQQCVPRTQC GCRDAQGRSL PTGTTWLSSG CTQNCTCRAG
TIQCQPFACS SGSHCQTNSN GSSTCAPHKL ERCSIFGDPH YRTFDGVSYH FQGRMTYILV
KTVDTLPRNV VPLVVEGRNK MHTPLSQIFL QEVIVIVYGY TVQLQADLQL VVNDQKMDTP
FNPNQQLQVT IRSNRLYLIT DFEFTVSFDG KSNAVISLPS TYQGLVCGLC GNFDKNQDNE
FMLPNGALTQ NLNHFGNSWE VKTKGGLPRF SRSIQEEEEE GDEKAGFHVS ECSPEQLQFI
NSTQACRVLV DPQGPFAACH QIVAPEPFQE HCLSDLCATR DPEEQEELRC QVLGAYAIIC
QEAGATLVSW RDHTHCALAC PANTIYQSCM TPCPASCANL AAPRDCEGPC VEGCASLPGY
VYSGARSLPL ALCGCTNNGI YYQRGDTFVT EDCSQRCTCV SSERLLCEPL SCSEGEICTL
GNRTRGCFRE SPCLRNPCQN DGHCQEQGAH FTCECGLGYG GDLCTELRDV PLPEKPEVSN
FAAILLGMLL PVVVIALAVV RECVSKRRRR EKTQSQNRAR LADTGSAALQ GEEGHPGP
//
