ID S7Q1I7_MYOBR Unreviewed; 525 AA.
AC S7Q1I7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Tubulin-specific chaperone E {ECO:0000256|ARBA:ARBA00015004};
DE AltName: Full=Tubulin-folding cofactor E {ECO:0000256|ARBA:ARBA00030180};
GN ORFNames=D623_10010305 {ECO:0000313|EMBL:EPQ17133.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ17133.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TBCE family.
CC {ECO:0000256|ARBA:ARBA00006286}.
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DR EMBL; KE164339; EPQ17133.1; -; Genomic_DNA.
DR RefSeq; XP_014384777.1; XM_014529291.1.
DR AlphaFoldDB; S7Q1I7; -.
DR GeneID; 102260073; -.
DR KEGG; myb:102260073; -.
DR CTD; 6905; -.
DR eggNOG; KOG3207; Eukaryota.
DR OrthoDB; 11880at2759; -.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR CDD; cd17044; Ubl_TBCE; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR044079; Ubl_TBCE.
DR PANTHER; PTHR15454:SF7; DYNEIN AXONEMAL LIGHT CHAIN 1; 1.
DR PANTHER; PTHR15454; NISCHARIN RELATED; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR Pfam; PF14580; LRR_9; 1.
DR Pfam; PF14560; Ubiquitin_2; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS51450; LRR; 1.
PE 3: Inferred from homology;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 27..71
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
SQ SEQUENCE 525 AA; 58467 MW; 2B5FBA6E1F902479 CRC64;
MNDTLTSDVV GRRVSVNGEC ATVRFYGTVP PVAGLWLGVE WDNPERGKHD GSHGGTVYFK
CSHPTGGSFI RPHKANFGVD FLTALRDRYE DEPEDDAKKQ IVTIGNIPVE TIGFGSVIKK
QSQLSELRDI SLRSCAVSCA GDKGDIASTC PNIRVVNLSQ NLLSAWEEVT DIAEQLRHLE
VLDLSENKLR FPPGSPAPVG TFSALKVLVL NRTGITWAEV LHCAQGWPAL EELYLKSNNI
SISERPADVL QLVRLLDLSS NQSIDENELF LIAYLPRLER LILADTGISA LHFPDAGVGC
KTAMFPSLQS LVLDDNRISQ WSVINELDKL QSLHSLSCLR NPLTVGSGAK THLQFIIAKI
GQLRTLNRCE IRPEERRGAE LDYRKAFGKE WKEAGGHQDP DQDRPSEAFL AAHPRYQALC
RKYGAPEDGE LKTQQPFLLK NQLLTLKINC PDRPDQKALE KQLPDSMTIQ KVKGLLSRLL
KVPVSDLLLA YESPKMPGRE IELENDQQSL QFYSVENGDC LLVRW
//
