ID S7QBX9_MYOBR Unreviewed; 1076 AA.
AC S7QBX9;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Tubulin-specific chaperone D {ECO:0000256|ARBA:ARBA00015003};
GN ORFNames=D623_10007425 {ECO:0000313|EMBL:EPQ18597.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ18597.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- SIMILARITY: Belongs to the TBCD family.
CC {ECO:0000256|ARBA:ARBA00006853}.
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DR EMBL; KE164547; EPQ18597.1; -; Genomic_DNA.
DR AlphaFoldDB; S7QBX9; -.
DR eggNOG; KOG1943; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0048487; F:beta-tubulin binding; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0007023; P:post-chaperonin tubulin folding pathway; IEA:InterPro.
DR GO; GO:0007021; P:tubulin complex assembly; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR033162; TBCD.
DR InterPro; IPR022577; Tubulin_specific_chaperoneD_C.
DR PANTHER; PTHR12658; BETA-TUBULIN COFACTOR D; 1.
DR PANTHER; PTHR12658:SF0; TUBULIN-SPECIFIC CHAPERONE D; 1.
DR Pfam; PF12612; TFCD_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000052978}.
FT DOMAIN 703..893
FT /note="Tubulin-specific chaperone D C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12612"
FT REGION 136..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 995..1076
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1076 AA; 118083 MW; B743BA38C37F2D09 CRC64;
MSNKILGCEK QTNEKPQFIT RPDVKQKMAD FLDWSLCTLA RSSFQTIEGV ITMDGMLQAL
AQIFKHGKRD DCLPYAATVL KCLDGCRIPD SNQTLLRKLR VKLVQRLGLT FLKPRVAKWR
YQRGCRSLAA NLQASTQSQR EARTHVETPD SEEGYDVPEE VESVIEQLLV GLKDKDTVVR
WSAAKGIGRV AGRLPQELAD DVVGSVLDCF SFQETDNAWH GGCLALAELG RRGLLLPPRL
PDVVPVILKA LTYEEKRGAC SVGDNVRDAA CYVCWAFARA YEPQELKPFV AEISSALVIA
TVFDRNVNCR RAASAAFQEN VGRQGTFPHG IDILTTADYF AVGNRSNCFL VISMFIAGFP
EYTRPMIDHL LTMKISHWDG VIRELSAKAL HNLVQQAPEY SAAQVFPRLL SMTQSTDLHT
RHGAVLTCAE VAHSLYRLAV REGRPVADYL DETVVQGLKQ IHQQLYDRQL YRGLGGELMR
QAVCVLIENL SLSKMPFRGD AVVDGWQWLI SDTLRNLHHV SSHSRQQIKE AAVSALAALC
SEYYAEEPGK ADSAGQEGLV EKYLAELQSP EEMTRCGFAM ALGALPGFLL RGRLQQVLAG
LRAVTLSSED VSFAESRRDA VKAIARICQT VGVRAEGTPD EVVCKANVSQ VYSTLLDCLR
DYTTDSRGDV GAWVREAAMT SLMDLTLLLG RDQPELIEAP TCQRVMCCLA QQASEKIDHF
RAHAAHVFMT LLHAAGSAGP TVPHVPHRAE LEQLFPRSEA ASVNWTAPSQ AFPRITQLLG
LPAYRYHVLL GLAVSVGGLT ESTVRHSTQS LFAHMKGIQN DPQALESFSG TLLQVFEDNL
LNDRVSVPLL KMLDQMLANG CFDIFTAEED HPFCVKLLEL CKAETSKSKD VQKLRSSIAV
FCGMAQFPGG VRRKVLLQLL LLLCHPFPVI RKTTASQVYE MLLTYSGVVG ADVLDEVMAV
LSDTAWDLEL LLVRGHRNRL CDLLGVPRPQ LVPKVTARPP RAAPGTPGVL SGPGLPTAPT
SYCPELQPRH LGPPGFQDPG GQHPHGSPPG SLVQVQGRCG SVSPPGTRAE VAGGAW
//
