ID S7RYZ7_GLOTA Unreviewed; 1727 AA.
AC S7RYZ7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=p-loop containing nucleoside triphosphate hydrolase protein {ECO:0000313|EMBL:EPQ58654.1};
GN ORFNames=GLOTRDRAFT_57763 {ECO:0000313|EMBL:EPQ58654.1};
OS Gloeophyllum trabeum (strain ATCC 11539 / FP-39264 / Madison 617) (Brown
OS rot fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Gloeophyllales; Gloeophyllaceae; Gloeophyllum.
OX NCBI_TaxID=670483 {ECO:0000313|EMBL:EPQ58654.1, ECO:0000313|Proteomes:UP000030669};
RN [1] {ECO:0000313|EMBL:EPQ58654.1, ECO:0000313|Proteomes:UP000030669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11539 {ECO:0000313|EMBL:EPQ58654.1,
RC ECO:0000313|Proteomes:UP000030669};
RX PubMed=22745431; DOI=10.1126/science.1221748;
RA Floudas D., Binder M., Riley R., Barry K., Blanchette R.A., Henrissat B.,
RA Martinez A.T., Otillar R., Spatafora J.W., Yadav J.S., Aerts A., Benoit I.,
RA Boyd A., Carlson A., Copeland A., Coutinho P.M., de Vries R.P.,
RA Ferreira P., Findley K., Foster B., Gaskell J., Glotzer D., Gorecki P.,
RA Heitman J., Hesse C., Hori C., Igarashi K., Jurgens J.A., Kallen N.,
RA Kersten P., Kohler A., Kuees U., Kumar T.K.A., Kuo A., LaButti K.,
RA Larrondo L.F., Lindquist E., Ling A., Lombard V., Lucas S., Lundell T.,
RA Martin R., McLaughlin D.J., Morgenstern I., Morin E., Murat C., Nagy L.G.,
RA Nolan M., Ohm R.A., Patyshakuliyeva A., Rokas A., Ruiz-Duenas F.J.,
RA Sabat G., Salamov A., Samejima M., Schmutz J., Slot J.C., St John F.,
RA Stenlid J., Sun H., Sun S., Syed K., Tsang A., Wiebenga A., Young D.,
RA Pisabarro A., Eastwood D.C., Martin F., Cullen D., Grigoriev I.V.,
RA Hibbett D.S.;
RT "The Paleozoic origin of enzymatic lignin decomposition reconstructed from
RT 31 fungal genomes.";
RL Science 336:1715-1719(2012).
CC -!- SIMILARITY: Belongs to the helicase family. Dicer subfamily.
CC {ECO:0000256|PROSITE-ProRule:PRU00657}.
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DR EMBL; KB469298; EPQ58654.1; -; Genomic_DNA.
DR RefSeq; XP_007863123.1; XM_007864932.1.
DR STRING; 670483.S7RYZ7; -.
DR GeneID; 19307196; -.
DR KEGG; gtr:GLOTRDRAFT_57763; -.
DR eggNOG; KOG0701; Eukaryota.
DR HOGENOM; CLU_000907_4_0_1; -.
DR OMA; TRKNHAY; -.
DR OrthoDB; 342391at2759; -.
DR Proteomes; UP000030669; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd18034; DEXHc_dicer; 1.
DR CDD; cd00593; RIBOc; 2.
DR Gene3D; 1.20.1290.10; AhpD-like; 1.
DR Gene3D; 3.30.160.380; Dicer dimerisation domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.1520.10; Ribonuclease III domain; 2.
DR InterPro; IPR029032; AhpD-like.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR038248; Dicer_dimer_sf.
DR InterPro; IPR005034; Dicer_dimerisation_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000999; RNase_III_dom.
DR InterPro; IPR036389; RNase_III_sf.
DR PANTHER; PTHR14950; DICER-RELATED; 1.
DR PANTHER; PTHR14950:SF37; ENDORIBONUCLEASE DICER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF03368; Dicer_dimer; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00636; Ribonuclease_3; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00535; RIBOc; 2.
DR SUPFAM; SSF69118; AhpD-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF69065; RNase III domain-like; 2.
DR PROSITE; PS51327; DICER_DSRBF; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS00517; RNASE_3_1; 1.
DR PROSITE; PS50142; RNASE_3_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EPQ58654.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030669};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00657}.
FT DOMAIN 27..201
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 369..543
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 561..661
FT /note="Dicer dsRNA-binding fold"
FT /evidence="ECO:0000259|PROSITE:PS51327"
FT DOMAIN 949..1087
FT /note="RNase III"
FT /evidence="ECO:0000259|PROSITE:PS50142"
FT DOMAIN 1125..1272
FT /note="RNase III"
FT /evidence="ECO:0000259|PROSITE:PS50142"
FT REGION 532..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1422..1444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1727 AA; 193888 MW; CC9317A82142DA9B CRC64;
MQLVNGLPTT MEEVNESLLP RRYQEEIFCR AQEGNVIAAL DTGSGKTFIS TLLIKWIAAR
DFGQGKVIVF LVPKVALVEQ QGNFISKQTP LRVTKCYGAM AIDLSDRGRW KKEFDNSDVL
VMTAQIFLNI LTHSHWSMEK VSLLVFDECH HCRKNHAYNG IMREYFQCPS PLRPKIFGMT
ASPIWNPKDA VESLATLERN MDAKVIAVRE HVSELLDHSP RPKEIIQPYP PSPEVYESYP
TPTLWNRLQV LNLPDEMEIP WDKIQTRYAV TYHSLGPYGA ELYLYSEMKQ RLVLLVDQTN
GHEYNGGLDY SGMDVDGLDN AYAIQFEPEL RQIGAVLCDY TAFFGEDDSD LTKFRVPFSL
EWCSPKFKVL VDLLVKHYTQ TFQGIIFVEQ RHVAACLAKV LLRVPYLQGF IKSAELIGHG
ATSVAKSQLK GMALKTQQDV VKSFREKEVN LLIATSVAEE GLDFPACDVV VRFDPIQHMV
GYVQSRGRAR HQTSTFVIMV QENHAADLAR YRAFVESEPE LKRVYQRADP VIQKSTVEED
DEDDGADPAD LAERERYVVP STGAILTYNS AISLLNHLCS LIPRDRFTPV HLPKYSGDFQ
STLELPLSLP LPSDKLTYVG PMKRSKKEAK RAVAFMAVMQ LHRLNVFDDY LLPAKSSSGA
DTEDADGRPI LDVSDVPETM DVMVRDPFVI HQKMWLHVIT LDGKRTAGLV TGTQLPLEVM
MCNGHEIRVH RAMRVIFDDE QRQRELLQTY TKMGIWWCIT GRAIQNPLSV FLVPLRETQS
QPDWCAMEHA ALFPWGNPDW TIITEEHHGR LMVVNSKDHG RPLLLRRVRR DLTPMSKPPK
GSREGCFPTY RDYVLHLYTR KGIPPEVPED GPLLEVQPFP RHSSGLYALH SLGQEDDKPV
ANVPNAQFLP QSLCRWIGLS EDIYRTFHVL PKVLHRITDV YRAGRARFEL GLPAIGTDLL
VEAYTLPSAN TGFSNQRLET LGDSVLKLCT VVHLFNKFPH RHEGQLDILR RNSVSNRTLL
ARAKENGLEH FLTGETQSLR TWRYTLAEGL SSMPEGHVIR SSPRRYPRRS LQDCMEATLG
AGFRMGGIPM ALQTGTALGL CLGGPLPWTL RYSRHPLSTP VPPLFTALQD TLGYEFHRSE
LLVEAVTHPS FRSAVSSSYQ RLEFLGDALI DLVVMHYLFK KFPEATSGQL SWARSRAVCA
PALASVAVKK LSLHQILLVN NVELSMAISK YVPVLEDTTP EHIVNNGWKH DPPKALSDVL
ESVMGAILVD SAYDYERASV IAEAVMEDVL DVLSPNLPRD PVSELMISTA RAGCRKMSYR
KTASNPDSKR NDSISVVVHD VVIVGPVSAA NLSLAKGRAS EEARSILQDP NSDKYLPKIC
TCAQAMAVDT PEDVDEVDED HKPLDDETEE GFAMMARKKL VEAESDGPKH EEEEDLSSGD
DSADERMVEE MILNGLARTA LPSSCSFLTD RWRGTDAMAS LANTAFLNRL KTIYPHAASA
GSKGMQVVSN PWYILTTVGF SGSNRPESVP AVFRHVLDDL AGVHKKENVT HAQAHNEKLL
LARKFRDSLF KSGLTTGYPR AINSMVSLHE AMPEELRDTR PLRNLQTPIE EYMRRGENLF
RSMYGETADP VQKLLDSILP DMGWFSNTIG YGATYGFTEV TTPLETSFIL VAALISVDTP
RQINWHLGNA RRTGATLEQV KAARQIVMEV AETSGVRWKD GVPEIKE
//
