ID S7TGR0_DESML Unreviewed; 646 AA.
AC S7TGR0;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Diguanylate cyclase with PAS/PAC sensor {ECO:0000313|EMBL:EPR35981.1};
GN ORFNames=dsmv_0686 {ECO:0000313|EMBL:EPR35981.1};
OS Desulfococcus multivorans DSM 2059.
OC Bacteria; Thermodesulfobacteriota; Desulfobacteria; Desulfobacterales;
OC Desulfococcaceae; Desulfococcus.
OX NCBI_TaxID=1121405 {ECO:0000313|EMBL:EPR35981.1, ECO:0000313|Proteomes:UP000014977};
RN [1] {ECO:0000313|EMBL:EPR35981.1, ECO:0000313|Proteomes:UP000014977}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2059 {ECO:0000313|EMBL:EPR35981.1,
RC ECO:0000313|Proteomes:UP000014977};
RX PubMed=23950126;
RA Brown S.D., Hurt R.A.Jr., Gilmour C.C., Elias D.A.;
RT "Draft genome sequences for three mercury-methylating, sulfate-reducing
RT bacteria.";
RL Genome Announc. 1:e00618-e00613(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPR35981.1}.
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DR EMBL; ATHJ01000105; EPR35981.1; -; Genomic_DNA.
DR RefSeq; WP_020877797.1; NZ_FUWN01000001.1.
DR AlphaFoldDB; S7TGR0; -.
DR STRING; 897.B2D07_16090; -.
DR PATRIC; fig|1121405.3.peg.3410; -.
DR eggNOG; COG3706; Bacteria.
DR OrthoDB; 9805474at2; -.
DR Proteomes; UP000014977; Unassembled WGS sequence.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR46663; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR PANTHER; PTHR46663:SF2; GGDEF DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08448; PAS_4; 2.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000014977};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..646
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011688820"
FT DOMAIN 101..155
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 296..346
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 414..468
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 500..633
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT REGION 624..646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 646 AA; 73675 MW; EA27B4D9C892B53F CRC64;
MKWLGLLMCL TFFMGGSQGH AFVSVGQAQM IYDGKLPVEL QNHNIMALLI DPESGAIVDA
NRKAVVFYGY PLDRMRGMRI QEINILDPRD VEAEYKRAEK EDRNYFIFPH RLADGEVRTV
EVYSAPVPDS SGKRLLLSII HDATHKALME AELNRYKDRL ETLVAQRTRQ LSDAHKRIDR
LSIFGLLVVS GLLFFLLRRH QKAVYFQHRF ELERERQRSE AALMEREERF QRMLALVPDM
ITIQDPEMNI LYSNWNGMGA VEPEKRILGT KCHQTYRGYD DICPDCRPIS VLDTKTPFQE
EIRLPDGTWL DMRVIPILDA NGEVECFVEW ARDITEQKQA QKELLAQKNL LEGVIDAIHD
LLTIQHPDRT IALCNKAACE AFGTTVEAAR HKKCYELIGR DRECDICATR KVHETGEPAE
LEKFMPELGV HLHCCSNPIL DQDGRIVYIV EQMRDITENH RTRERLERLA TTDALTELWN
RAYFMGTIRK EMERARRYGE PFSLLMLDLD HFKRVNDTRG HAAGDAALRH VAAIFRKSLR
QTDIAGRVGG EEFSILLPHT DLAAALVMAE RLRSTIENTP ADYNGTEIPL TSSIGVAVYD
REIADEDALM LLADEALYAA KKGGRNRVCQ PPREKGAAFP GTSDVG
//
