ID S7TQE2_DESML Unreviewed; 463 AA.
AC S7TQE2;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=PAS modulated sigma54 specific transcriptional regulator, Fis family {ECO:0000313|EMBL:EPR39191.1};
GN ORFNames=dsmv_2695 {ECO:0000313|EMBL:EPR39191.1};
OS Desulfococcus multivorans DSM 2059.
OC Bacteria; Thermodesulfobacteriota; Desulfobacteria; Desulfobacterales;
OC Desulfococcaceae; Desulfococcus.
OX NCBI_TaxID=1121405 {ECO:0000313|EMBL:EPR39191.1, ECO:0000313|Proteomes:UP000014977};
RN [1] {ECO:0000313|EMBL:EPR39191.1, ECO:0000313|Proteomes:UP000014977}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2059 {ECO:0000313|EMBL:EPR39191.1,
RC ECO:0000313|Proteomes:UP000014977};
RX PubMed=23950126;
RA Brown S.D., Hurt R.A.Jr., Gilmour C.C., Elias D.A.;
RT "Draft genome sequences for three mercury-methylating, sulfate-reducing
RT bacteria.";
RL Genome Announc. 1:e00618-e00613(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPR39191.1}.
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DR EMBL; ATHJ01000091; EPR39191.1; -; Genomic_DNA.
DR RefSeq; WP_020877452.1; NZ_FUWN01000004.1.
DR AlphaFoldDB; S7TQE2; -.
DR STRING; 897.B2D07_17460; -.
DR eggNOG; COG3829; Bacteria.
DR OrthoDB; 5413348at2; -.
DR Proteomes; UP000014977; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR002078; Sigma_54_int.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR32071:SF95; TRANSCRIPTIONAL REGULATORY PROTEIN ZRAR; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF13426; PAS_9; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000014977};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 6..51
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 77..134
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 148..377
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 463 AA; 51939 MW; 119367C739A40BEB CRC64;
MFETEMNNYW KTVVDTIQDG VMIVDKDGTI VSVNRGMVRM TGYEKAEIVG KPCSFLNCDT
CEIARERKGD HWCVLFRTGA MNMRRCTFSR KDGRPVHVLK NASLLRDRDG VVLGAVETMT
DVSELVEKDT QIEAFRRELR QEDGFHGILG TSAPMQRVFD LIANAARSEA PVIILGESGT
GKELAAKAIH DIRGDDRRPF VKVNCASLNP ALLESELFGH VKGAFTGAYR SREGRFAAAG
GGDIFLDEIG DIPLSVQVKL LRVLEEKVVE RVGDHTPIPI NVRILSATNR NLTEMVREGA
FREDLFYRIN VIPIHIPPLR ERPGDISLLA DHFFRRIRLK SGKKIEGISR EAMRLLAAYP
WPGNVREMKS AFEFAFVSCR DDVILPRHFP PALFGGGTSP APGPPEAAPH PLEEAQAKRR
RLVQALEAAD GNQSEAARIL GVSRVTVWHW MKRYQIRFER KIK
//
