GenomeNet

Database: UniProt
Entry: S7UKH8_DESML
LinkDB: S7UKH8_DESML
Original site: S7UKH8_DESML 
ID   S7UKH8_DESML            Unreviewed;       374 AA.
AC   S7UKH8;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   08-MAY-2019, entry version 28.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=dsmv_0805 {ECO:0000313|EMBL:EPR34339.1};
OS   Desulfococcus multivorans DSM 2059.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfobacterales;
OC   Desulfobacteraceae; Desulfococcus.
OX   NCBI_TaxID=1121405 {ECO:0000313|EMBL:EPR34339.1, ECO:0000313|Proteomes:UP000014977};
RN   [1] {ECO:0000313|EMBL:EPR34339.1, ECO:0000313|Proteomes:UP000014977}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 2059 {ECO:0000313|EMBL:EPR34339.1,
RC   ECO:0000313|Proteomes:UP000014977};
RX   PubMed=23950126;
RA   Brown S.D., Hurt R.A.Jr., Gilmour C.C., Elias D.A.;
RT   "Draft genome sequences for three mercury-methylating, sulfate-
RT   reducing bacteria.";
RL   Genome Announc. 1:e00618-13(2013).
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EPR34339.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; ATHJ01000116; EPR34339.1; -; Genomic_DNA.
DR   RefSeq; WP_020878159.1; NZ_FUWN01000003.1.
DR   STRING; 1121405.dsmv_0805; -.
DR   EnsemblBacteria; EPR34339; EPR34339; dsmv_0805.
DR   PATRIC; fig|1121405.3.peg.3817; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000014977; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000014977};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014977};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
SQ   SEQUENCE   374 AA;  41222 MW;  2180B4B71EF824C1 CRC64;
     MSPEMQRTYD VRVKEFVPLL PPQALKEEIP ISWTAGDTVI AGRKAIERIL HKEDPRLLVI
     TGPCSIHNEE EALEYAERLN ALREAVSETL CIVMRVYFEK PRTNVGWKGM INDPYMDGSC
     DIVEGLRRAR RLLLKITEMG MPTATEMLDP ISPQYIAGLV CWSAIGARTT ESQTHREMAS
     GLSMPVGFKN CTDGGLTTAV NAMIAAGSPQ SFLGIDADGR SAVVKTTGNQ YAHIVLRGGR
     RPNYDSVSIR EAVDQLRAKN LLEAIIVDCS HANSSKKYQN QARVWQDCIN QRLDGNDAIV
     GLMLESNLRE GNQKLTDDPC RLAYGVSITD ACISWETTEA LIRSAHEQLL RSRRGNSGDA
     ALSGNGRYKV AVTA
//
DBGET integrated database retrieval system