GenomeNet

Database: UniProt
Entry: S7ULN5_9DELT
LinkDB: S7ULN5_9DELT
Original site: S7ULN5_9DELT 
ID   S7ULN5_9DELT            Unreviewed;       453 AA.
AC   S7ULN5;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   16-JAN-2019, entry version 40.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=dsat_2583 {ECO:0000313|EMBL:EPR34764.1};
OS   Desulfovibrio alkalitolerans DSM 16529.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC   Desulfovibrionaceae; Desulfovibrio.
OX   NCBI_TaxID=1121439 {ECO:0000313|EMBL:EPR34764.1, ECO:0000313|Proteomes:UP000014975};
RN   [1] {ECO:0000313|EMBL:EPR34764.1, ECO:0000313|Proteomes:UP000014975}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16529 {ECO:0000313|EMBL:EPR34764.1,
RC   ECO:0000313|Proteomes:UP000014975};
RX   PubMed=23950126;
RA   Brown S.D., Hurt R.A.Jr., Gilmour C.C., Elias D.A.;
RT   "Draft genome sequences for three mercury-methylating, sulfate-
RT   reducing bacteria.";
RL   Genome Announc. 1:e00618-13(2013).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EPR34764.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; ATHI01000006; EPR34764.1; -; Genomic_DNA.
DR   RefSeq; WP_020886468.1; NZ_ATHI01000006.1.
DR   EnsemblBacteria; EPR34764; EPR34764; dsat_2583.
DR   PATRIC; fig|1121439.3.peg.984; -.
DR   OrthoDB; 219876at2; -.
DR   Proteomes; UP000014975; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000014975};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014975}.
FT   DOMAIN      148    285       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      362    430       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     156    163       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      227    247       {ECO:0000256|SAM:Coils}.
FT   COILED      314    341       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   453 AA;  51046 MW;  A37262F68E4F807F CRC64;
     MKHGWEHILE ILEKRLNPGL FKVWIKPLNA EFKGGDLVLT APNDFVASWV RDRLVGMIRE
     AASQALGVSP EIVVRAASAK PALAGAKPAL VTSAMRTMDV ACGRSASSEP ATAAPSYQWR
     FSFDDFVVGP NNALAHAASQ SVCRQSLSTD QLFLCSAPGL GKTHLLQAIG KQLFQEANVR
     RVRLRYLTAE EFATRMVMAL RMNEIDRFKS EFRENVDLLL MEDIHFLQGK EKIQDELLAT
     LKALQERGSK VVFTSSFLPK ELSGVDSHLA SRFGSGFLTV IERPDFETRM RIVEQKARSL
     YQVHLPEDVS SVLAERIRSD IRQLESCLQN LILKARLMRE QITMEMALQV LSNYAQEQES
     PDIGRIIDAV CRTFRLAPPE LASKSRKQGV VMARNTAFFL ARKYTDLSLN DIGRHFNRKH
     STVLKGITKV EREISRRTPH GRQFERALEV LDL
//
DBGET integrated database retrieval system