ID   S7VT66_9FLAO            Unreviewed;       694 AA.
AC   S7VT66;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=adenosine deaminase {ECO:0000256|ARBA:ARBA00012784};
DE            EC=3.5.4.4 {ECO:0000256|ARBA:ARBA00012784};
GN   ORFNames=ADIWIN_2447 {ECO:0000313|EMBL:EPR72557.1};
OS   Winogradskyella psychrotolerans RS-3.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Winogradskyella.
OX   NCBI_TaxID=641526 {ECO:0000313|EMBL:EPR72557.1, ECO:0000313|Proteomes:UP000014962};
RN   [1] {ECO:0000313|EMBL:EPR72557.1, ECO:0000313|Proteomes:UP000014962}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RS-3 {ECO:0000313|EMBL:EPR72557.1,
RC   ECO:0000313|Proteomes:UP000014962};
RX   PubMed=23950132;
RA   Kumar Pinnaka A., Ara S., Singh A., Shivaji S.;
RT   "Draft Genome Sequence of Winogradskyella psychrotolerans RS-3T, Isolated
RT   from the Marine Transect of Kongsfjorden, Ny-Alesund, Svalbard, Arctic
RT   Ocean.";
RL   Genome Announc. 1:e00630-e00613(2013).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPR72557.1}.
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DR   EMBL; ATMR01000117; EPR72557.1; -; Genomic_DNA.
DR   AlphaFoldDB; S7VT66; -.
DR   STRING; 641526.ADIWIN_2447; -.
DR   PATRIC; fig|641526.4.peg.2430; -.
DR   eggNOG; COG1816; Bacteria.
DR   Proteomes; UP000014962; Unassembled WGS sequence.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:UniProt.
DR   GO; GO:0004126; F:cytidine deaminase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 2.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF43; ADENOSINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:EPR72557.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014962}.
FT   DOMAIN          578..673
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   694 AA;  81972 MW;  B5729D4DB08FC5A6 CRC64;
     MNHPTSFSDK FELLEKDLSL LTKVSNSSKQ SKKELKILIY KAAYIRHKLF CFVNRIDDDF
     NIDLSKESNL LDSSDLVMNL TELIKRIQVL RFDLGHRFLH QGNYEVLDYA LPKNIHQENL
     KKSYVFYGER KLLYDCFKLI YSGNKAFESY IHLFHAYLLI KAQFRSELIQ VNDKVGFGNF
     SKYQNRKEYF LQDNSLYHTA FMNLAVHDTK KHMNLKSFEL RVAPKSDVYK LKNSISGYNE
     AVKKNAIQSE QKNRQKTSKY SLAKNGIFYI IHYIKKKDKQ KCADLSSEIL CRHHVSRKEI
     KDQSVAISKL RESYSDLSDL IRGIDAASSE FNASPEVFAQ GFRYLKNHKL KGKYNHLRQK
     LEEPKIYATY HVGEDFYDIT DGLRSIDECI NFFNLKQGDR IGHALALGID VKDYYQFKQG
     KLMLPKETIL DNVVWLLAKI RKFGISIHRN EVNRLEKLFE SLYYELYSHN FDDGNRIKNK
     HIHHTSFYDA WKLRGDDPYL YLEDLDSDVY KKINLTYWER CRINEEYPRN KNLRNQIDLK
     ILYQQYHFNS KIKKKGKEIK QFEITHAYME LVEQVQHNMQ HELKNRNIAI ETNPTSNYLI
     GTFKRYAKHP ITKFFNLGLE MDTDLIKKCP QLSVSINTDD QGIFSTSLEN EYALMAIALE
     KEKDDKGNLK YNSAMIYEWL ERVRLMGLGQ SFKD
//