ID   S7XIZ4_SPRLO            Unreviewed;       275 AA.
AC   S7XIZ4;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=Protein tyrosine phosphatase {ECO:0000313|EMBL:EPR79004.1};
GN   ORFNames=SLOPH_1518 {ECO:0000313|EMBL:EPR79004.1};
OS   Spraguea lophii (strain 42_110) (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Spraguidae;
OC   Spraguea.
OX   NCBI_TaxID=1358809 {ECO:0000313|EMBL:EPR79004.1, ECO:0000313|Proteomes:UP000014978};
RN   [1] {ECO:0000313|Proteomes:UP000014978}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=42_110 {ECO:0000313|Proteomes:UP000014978};
RX   PubMed=23990793; DOI=10.1371/journal.pgen.1003676;
RA   Campbell S.E., Williams T.A., Yousuf A., Soanes D.M., Paszkiewicz K.H.,
RA   Williams B.A.P.;
RT   "The genome of Spraguea lophii and the basis of host-microsporidian
RT   interactions.";
RL   PLoS Genet. 9:E1003676-E1003676(2013).
CC   -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC       receptor class subfamily. {ECO:0000256|ARBA:ARBA00009649}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPR79004.1}.
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DR   EMBL; ATCN01000449; EPR79004.1; -; Genomic_DNA.
DR   AlphaFoldDB; S7XIZ4; -.
DR   STRING; 1358809.S7XIZ4; -.
DR   VEuPathDB; MicrosporidiaDB:SLOPH_1518; -.
DR   HOGENOM; CLU_1115529_0_0_1; -.
DR   InParanoid; S7XIZ4; -.
DR   OMA; DELCKMR; -.
DR   OrthoDB; 1342035at2759; -.
DR   Proteomes; UP000014978; Unassembled WGS sequence.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR000242; PTP_cat.
DR   InterPro; IPR016130; Tyr_Pase_AS.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   InterPro; IPR000387; Tyr_Pase_dom.
DR   PANTHER; PTHR19134; RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE; 1.
DR   PANTHER; PTHR19134:SF449; RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE GAMMA; 1.
DR   Pfam; PF00102; Y_phosphatase; 1.
DR   PRINTS; PR00700; PRTYPHPHTASE.
DR   SMART; SM00194; PTPc; 1.
DR   SMART; SM00404; PTPc_motif; 1.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR   PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR   PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014978}.
FT   DOMAIN          68..275
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   DOMAIN          195..267
FT                   /note="Tyrosine specific protein phosphatases"
FT                   /evidence="ECO:0000259|PROSITE:PS50056"
SQ   SEQUENCE   275 AA;  32732 MW;  B10FB4DE4C627D62 CRC64;
     MKQTSLENED FLGEINNQNI LKKKSENEVN NTIKSVLDKI KKNVLLMIHK KEYDNALKVI
     TKDLRIFYQE KRDYDRFNIT PYTDDLIKKY NLNSYVNASE IIHEKITYFP CQFPKKRYSE
     NFLNFLEKTG VSLIISLIPI EEDDYFTGIY LKNKIEHKDS KGNVIFYKEE YEINNKNYIR
     LRYLRWEDFD VPDKEEFGFF YNEYKGIRSL HKNIAVHCLA GVGRTGVTIM YDILCNMNYV
     DEGIFLDTLL MLRQSRPCLV YTAEQLKFLA DIFIA
//