ID S7ZAL5_PENO1 Unreviewed; 587 AA.
AC S7ZAL5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 13-SEP-2023, entry version 27.
DE RecName: Full=Purine permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=PDE_02207 {ECO:0000313|EMBL:EPS27264.1};
OS Penicillium oxalicum (strain 114-2 / CGMCC 5302) (Penicillium decumbens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=933388 {ECO:0000313|EMBL:EPS27264.1, ECO:0000313|Proteomes:UP000019376};
RN [1] {ECO:0000313|EMBL:EPS27264.1, ECO:0000313|Proteomes:UP000019376}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=114-2 / CGMCC 5302 {ECO:0000313|Proteomes:UP000019376};
RX PubMed=23383313; DOI=10.1371/journal.pone.0055185;
RA Liu G., Zhang L., Wei X., Zou G., Qin Y., Ma L., Li J., Zheng H., Wang S.,
RA Wang C., Xun L., Zhao G.-P., Zhou Z., Qu Y.;
RT "Genomic and secretomic analyses reveal unique features of the
RT lignocellulolytic enzyme system of Penicillium decumbens.";
RL PLoS ONE 8:E55185-E55185(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; KB644410; EPS27264.1; -; Genomic_DNA.
DR AlphaFoldDB; S7ZAL5; -.
DR STRING; 933388.S7ZAL5; -.
DR eggNOG; ENOG502QQD4; Eukaryota.
DR HOGENOM; CLU_017959_7_0_1; -.
DR OrthoDB; 911690at2759; -.
DR PhylomeDB; S7ZAL5; -.
DR Proteomes; UP000019376; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019376};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 69..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 423..444
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 450..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 482..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 523..543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 565..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 587 AA; 61783 MW; 2DFFBC0E5167ECB1 CRC64;
MDGPDQIGPD HRPGRTVGDK LRRVVKTFTT RDGLLGSYDY AYLFIPRLPF TKRARKSAPF
FGLEDRVPVV LALILGLQHA LSMLAGVISP PIILGGSGGV NFGDELHQYL VSTSLIASGL
LSAMQMARFR IIGTKYFVGT GLLSVVGTSF ATITVATGTF SQMYKSGYCP TDADGNRLPC
PQGYGALLGT SCLCALLEIG LSFTSSRILS RIFPALVTGP TVLLIGASLI QSGMQDWAGG
TGCVPASSTA PRPLCPSASA PHALPWGSPE FIGLGFLVFV TIILCERFGP PILKSCAVVV
GLVVGSIVAA ACNYFESSGI TAAPVASFPW VRTFPLSIYP PLILPLLALY IVLLMESIGD
IAATCDVSRL AVEGATFDSR IQGGVLGNGL TSIIAGLMTI SPMSVFAQNN GVIALTKCAN
RTAGFCCCFF LVIMGIFSKF AAALVSIPSA VLGGMTTFLF SSVAVSGIRI ISTIDFTRRN
RFILTASFSL GMGITLVPNW WGYVFTYEGD NHALAGLLNA VDLVMENGFA VCAIMGVILN
LIIPEEADDA PAVFHSADPD EVAQTPTVTG LGEDASGKME HPMPMIK
//
