ID   S7ZVW3_PENO1            Unreviewed;       414 AA.
AC   S7ZVW3;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Saccharopine dehydrogenase NADP binding domain-containing protein {ECO:0000259|Pfam:PF03435};
GN   ORFNames=PDE_07852 {ECO:0000313|EMBL:EPS32891.1};
OS   Penicillium oxalicum (strain 114-2 / CGMCC 5302) (Penicillium decumbens).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=933388 {ECO:0000313|EMBL:EPS32891.1, ECO:0000313|Proteomes:UP000019376};
RN   [1] {ECO:0000313|EMBL:EPS32891.1, ECO:0000313|Proteomes:UP000019376}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=114-2 / CGMCC 5302 {ECO:0000313|Proteomes:UP000019376};
RX   PubMed=23383313; DOI=10.1371/journal.pone.0055185;
RA   Liu G., Zhang L., Wei X., Zou G., Qin Y., Ma L., Li J., Zheng H., Wang S.,
RA   Wang C., Xun L., Zhao G.-P., Zhou Z., Qu Y.;
RT   "Genomic and secretomic analyses reveal unique features of the
RT   lignocellulolytic enzyme system of Penicillium decumbens.";
RL   PLoS ONE 8:E55185-E55185(2013).
CC   -!- SIMILARITY: Belongs to the saccharopine dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00038048}.
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DR   EMBL; KB644414; EPS32891.1; -; Genomic_DNA.
DR   AlphaFoldDB; S7ZVW3; -.
DR   eggNOG; KOG2733; Eukaryota.
DR   HOGENOM; CLU_031002_0_1_1; -.
DR   OrthoDB; 5479972at2759; -.
DR   PhylomeDB; S7ZVW3; -.
DR   Proteomes; UP000019376; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   PANTHER; PTHR12286:SF5; SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE; 1.
DR   PANTHER; PTHR12286; UNCHARACTERIZED; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019376};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        278..300
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        354..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          10..139
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
SQ   SEQUENCE   414 AA;  45227 MW;  24F8B4325E265425 CRC64;
     MTSNRQYDLV LLGPTGYTGR FCSEHIVQNL PTDLKWAIAG RSPQKIHPIA DELKKLNADR
     IQPDVLAVQL NSAELNDLAQ KTRLIINCVG PYHLYSTPVV EACAAHGTHY VDATGETPWV
     KLIIDKYHEK AKSNGAIIIP SVGVESAPAD ILAWALVKHV REEMATQTRQ IDCCIKEMKT
     SGASGGTLNT VLSIFDWLPP SEVMKSLNPF SLAASAPPKD IPSESLISKL IGARWIRDLG
     TVTTSPSGIA DVTIVHRSST LMPELYGKRF FFRQFLHVRN SLIGVAVHVG FLVGITLLMI
     PPIRALVRRF VFAPGQGPSS EASKHDRLEY HAVATADQEG PSPKRAFGKF SFDGGMYLLT
     GLLLAEAAIV ILNNEEKVKK VSRGGIVTSA TLGQDFVDRL EKVGCNIDTK TFQH
//