ID S8AAM5_DACHA Unreviewed; 1593 AA.
AC S8AAM5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00012494};
DE EC=2.7.7.48 {ECO:0000256|ARBA:ARBA00012494};
GN ORFNames=H072_6215 {ECO:0000313|EMBL:EPS39974.1};
OS Dactylellina haptotyla (strain CBS 200.50) (Nematode-trapping fungus)
OS (Monacrosporium haptotylum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Orbiliomycetes;
OC Orbiliales; Orbiliaceae; Dactylellina.
OX NCBI_TaxID=1284197 {ECO:0000313|EMBL:EPS39974.1, ECO:0000313|Proteomes:UP000015100};
RN [1] {ECO:0000313|EMBL:EPS39974.1, ECO:0000313|Proteomes:UP000015100}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 200.50 {ECO:0000313|EMBL:EPS39974.1,
RC ECO:0000313|Proteomes:UP000015100};
RX PubMed=24244185;
RA Meerupati T., Andersson K.M., Friman E., Kumar D., Tunlid A., Ahren D.;
RT "Genomic mechanisms accounting for the adaptation to parasitism in
RT nematode-trapping fungi.";
RL PLoS Genet. 9:E1003909-E1003909(2013).
RN [2] {ECO:0000313|Proteomes:UP000015100}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 200.50 {ECO:0000313|Proteomes:UP000015100};
RA Ahren D.G.;
RT "Genomic mechanisms accounting for the adaptation to parasitism in
RT nematode-trapping fungi.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517};
CC -!- SIMILARITY: Belongs to the RdRP family.
CC {ECO:0000256|ARBA:ARBA00005762}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPS39974.1}.
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DR EMBL; AQGS01000443; EPS39974.1; -; Genomic_DNA.
DR RefSeq; XP_011112012.1; XM_011113710.1.
DR STRING; 1284197.S8AAM5; -.
DR eggNOG; KOG0988; Eukaryota.
DR HOGENOM; CLU_243738_0_0_1; -.
DR OMA; DRVWTCW; -.
DR OrthoDB; 2735303at2759; -.
DR Proteomes; UP000015100; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR PANTHER; PTHR23079:SF14; RNA-DEPENDENT RNA POLYMERASE; 1.
DR Pfam; PF05183; RdRP; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022484};
KW Reference proteome {ECO:0000313|Proteomes:UP000015100};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 151..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 256..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 290..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 426..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 469..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 536..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..178
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..305
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..412
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 426..452
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..518
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 575..591
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1593 AA; 180323 MW; 1D4C789EDBACC179 CRC64;
MDVESCNCGN DIYTTSALPG SYQPIIKTTQ SMASSSFVIR DGMSFNDVFH ILKSKFDLPL
QPDDVSLVDK DTRSYIFQTK YLMTYAKRYL VAAVKDFEKF ADLDDFPKEV VSSAPSVQSK
KRRQEIIRKR RVKAFNEELR KQVILAKREG GSIVTQGNSR QSISSPSRPP TSGRSAISTQ
EDKKIRQKVI DWQDNSLHIR LSQLSMQEQE LEHDEEIHNA FTDPPDYIEE PTEIDSEVEE
ELLAAYFETP VTQNISPSGK RAIKPSLTPL PPKSPINILP STFHQEETLY SPPAKKVNST
NANWGIYKPP DVDFRPARVY TKPPFPSSAS KSSPPPQLPS SSDEMDENRK RKHQLVKSSA
PQTTDNIPPG RPAKRQSPFK NARPKMVDPP RPNSPGIFAT PNPISRSQEN QRPIVGAVGD
AGSFSTVSSM GSSSFQSDLP IIGTQPTSFG STDCPGRYDD AVGFEGYVGP SRGRPNFASS
SRNRELSQRT DISMESRPVM RQSPQPSDQL LRESSAYSRE SCAYSVGTSV EKEMAELDGP
GEPAFGRGHT FNSHGPKSAS VTPLIPASPT PSPEKRAPGQ ASDSGNNQPR RAQKYRLYDT
LGDEPFPGDG IPILASERTP YWLRYELTRL IMASSAKQCE PESLSALLES LIEKITSPSF
DRRHIGKELS LFMAAFTPDE THLAERLYED ALAVISRTEG QWDDRIQLNA EMTLNTTREI
IDTTRGTSRR IWRPVIQLKP LRLNAKSHRF GRHFGSHRFL TVRALKYDKY DNDVTKPGYE
DYQQLWTELL CERGFKLYGY RWRPMYFHQA KGNIKKWNQV IMFAEEGPGI TTMSVRNATE
WFIPIEPNKF QTQCKWWSRI KLGFSTTLPT VVFEPDQIKP LPDIYSNQGN CLTDGCGLVS
PAVLREVKRI HGLEFLPSAI QARIGSAKGL WVLDPDPKHL TSDELWIKIR PEQTKFNGIS
DDVAHRTLDI VGIASPLRSG YINAQFILIL QQNNISHDAL ANLLREDLRR EFGELLQPGR
IEDPVFIRAF LEKISVNSSR RGVERLGMNG RVPSDLAERC INLLESGFNL TNGNLKDWFS
KKLTRYFEKR KEKLHINIPK SCTVYCVADP SRKLKAGQVF LRFGQHSNFI DEKTLFPIDI
LIGDVLVTRN PAHTESDIQK VTAVDIPELR YLTNVIVFSA DKVTCDRSLA DYLSGGDYDG
DRVWTCWEPR LVDPFQNKPF DPADTTPYIE VDKKKMLEAF SPKKNSKAFP DFVRTQIQLS
LEESLLGKCT SFYYALVYKK ANLYHDSMND PEAKILAALC SKLVDGPKHG FRVRETCWKG
LCRTHNGLPE PLYKKKNLKS SDVTNAKTSQ NPMDRLRFQV AETEITSMLE SFEKLSEGAV
CKDKDILRCY DDFWNYYEKQ KNEWEKKRNT DAEDKYGDAL AVLGQLKRLN AALDPLYDKW
NNHFKGRISD DDLPLEDDRV TAGNQNLVDR LLDEYLNMKP IIGDPGLKTT SLIEYWALTA
DNVDSDWSRI RAAALHRKVY SLKTTSSPFP WYMAGDVFCR IKSVAVSPHE PPRSMTASMA
FSLKVRSSAL VKPEQIDWGS GIMDDYDDFD YDD
//
