ID S8AEN1_DACHA Unreviewed; 869 AA.
AC S8AEN1;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=DNA repair metallo-beta-lactamase domain-containing protein {ECO:0000259|Pfam:PF07522};
GN ORFNames=H072_4748 {ECO:0000313|EMBL:EPS41364.1};
OS Dactylellina haptotyla (strain CBS 200.50) (Nematode-trapping fungus)
OS (Monacrosporium haptotylum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Orbiliomycetes;
OC Orbiliales; Orbiliaceae; Dactylellina.
OX NCBI_TaxID=1284197 {ECO:0000313|EMBL:EPS41364.1, ECO:0000313|Proteomes:UP000015100};
RN [1] {ECO:0000313|EMBL:EPS41364.1, ECO:0000313|Proteomes:UP000015100}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 200.50 {ECO:0000313|EMBL:EPS41364.1,
RC ECO:0000313|Proteomes:UP000015100};
RX PubMed=24244185;
RA Meerupati T., Andersson K.M., Friman E., Kumar D., Tunlid A., Ahren D.;
RT "Genomic mechanisms accounting for the adaptation to parasitism in
RT nematode-trapping fungi.";
RL PLoS Genet. 9:E1003909-E1003909(2013).
RN [2] {ECO:0000313|Proteomes:UP000015100}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 200.50 {ECO:0000313|Proteomes:UP000015100};
RA Ahren D.G.;
RT "Genomic mechanisms accounting for the adaptation to parasitism in
RT nematode-trapping fungi.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA repair metallo-beta-lactamase (DRMBL)
CC family. {ECO:0000256|ARBA:ARBA00010304}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPS41364.1}.
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DR EMBL; AQGS01000251; EPS41364.1; -; Genomic_DNA.
DR RefSeq; XP_011110639.1; XM_011112337.1.
DR AlphaFoldDB; S8AEN1; -.
DR STRING; 1284197.S8AEN1; -.
DR eggNOG; KOG1361; Eukaryota.
DR HOGENOM; CLU_005260_4_0_1; -.
DR OMA; AQVHMHS; -.
DR OrthoDB; 23465at2759; -.
DR Proteomes; UP000015100; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006974; P:DNA damage response; IEA:UniProtKB-KW.
DR CDD; cd16273; SNM1A-1C-like_MBL-fold; 1.
DR Gene3D; 3.40.50.12650; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR011084; DRMBL.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR23240:SF6; DNA CROSS-LINK REPAIR 1A PROTEIN; 1.
DR PANTHER; PTHR23240; DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED; 1.
DR Pfam; PF07522; DRMBL; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000015100}.
FT DOMAIN 708..835
FT /note="DNA repair metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF07522"
FT REGION 1..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 86..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 351..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 627..659
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..114
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..245
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 628..645
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 869 AA; 96530 MW; BDCD1938668CD166 CRC64;
MPLPAKRKTP STSTPSKTPA KRPSTSALGS KGRPGANGNI LNFFKKVDGP APPGKNPNGN
HDLRKFGFTK GPRPARVGAL GVDLFYADGD DDEDGSNPGD SPRKNSEYRT WQDDDMTDLF
GPPGTQQREI LEAEEIDDNS DESDEDQLPP IRACTPPPPL STEVVPENNL CPFSFDDPVE
EPAGPGDIST ASVSNTNDFG PSGPFMLEEE ELPNIPAHPP QTLPSETDYG LNDDDFIEDE
GMENFDEEQD RRWKDAEDDD IDDEGEEVGE EKLNRKFMEQ EELDEAAFLA SLGPIDEGEG
ERKCTVSCPI CDVDLAGYKD DIVSRHVNCC LDGKPIPLPP RDIKPAVALG EKSPEKAPLH
PPRPAQSNPF AHPSVNTRTP SAFSKIMASN AEDRAWKEAA EEETRSRGKR SFQRTCPFYK
ILPNLNVAVD AFRYGAVEGT NAYFLSHFHS DHYIGLSSSW SHGPIYCSRV TANLCRRQLR
VDPQYIKELE YEKKTQIPGT GGATVTMIDA NHCPGSSLFL FEKMIPSPRG TRFQRILHCG
DFRASAKHLR HPLLSVAKKN KIDICYLDTT YLNPKYAFPP QRQVIDACME LCVSLDREVE
EGKELGFGES RKEGGGIEKF TVAKAPTADD LTSGNNNNNY NNNSESADDK GEEGSRTKTK
TKGRLLVVVG TYSIGKERIC MGIARALNCK IYAPANKQRI CAALEDQELN SRLTSDPHAA
QVHMTPLMEI RPETLRDYLA SFKQRFTKVV GFRPSGWNYR PPNSRFVESP QVQTVLHSQA
WRSDYGVAQM VPQRGSTAEV KCFGVPYSEH SSFRELTAFC CALDIVRVIP TVNVGSAKSR
EKMKMWFEKW AAEKKKNGFY VLEEGRDVL
//
