ID   S8APQ4_DACHA            Unreviewed;      1109 AA.
AC   S8APQ4;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=H072_1089 {ECO:0000313|EMBL:EPS44935.1};
OS   Dactylellina haptotyla (strain CBS 200.50) (Nematode-trapping fungus)
OS   (Monacrosporium haptotylum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Orbiliomycetes;
OC   Orbiliales; Orbiliaceae; Dactylellina.
OX   NCBI_TaxID=1284197 {ECO:0000313|EMBL:EPS44935.1, ECO:0000313|Proteomes:UP000015100};
RN   [1] {ECO:0000313|EMBL:EPS44935.1, ECO:0000313|Proteomes:UP000015100}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 200.50 {ECO:0000313|EMBL:EPS44935.1,
RC   ECO:0000313|Proteomes:UP000015100};
RX   PubMed=24244185;
RA   Meerupati T., Andersson K.M., Friman E., Kumar D., Tunlid A., Ahren D.;
RT   "Genomic mechanisms accounting for the adaptation to parasitism in
RT   nematode-trapping fungi.";
RL   PLoS Genet. 9:E1003909-E1003909(2013).
RN   [2] {ECO:0000313|Proteomes:UP000015100}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 200.50 {ECO:0000313|Proteomes:UP000015100};
RA   Ahren D.G.;
RT   "Genomic mechanisms accounting for the adaptation to parasitism in
RT   nematode-trapping fungi.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPS44935.1}.
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DR   EMBL; AQGS01000025; EPS44935.1; -; Genomic_DNA.
DR   RefSeq; XP_011107081.1; XM_011108779.1.
DR   AlphaFoldDB; S8APQ4; -.
DR   STRING; 1284197.S8APQ4; -.
DR   eggNOG; KOG2108; Eukaryota.
DR   HOGENOM; CLU_276941_0_0_1; -.
DR   OMA; GAKNECF; -.
DR   OrthoDB; 1330984at2759; -.
DR   Proteomes; UP000015100; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF30; F-BOX DNA HELICASE 1; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50181; FBOX; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015100}.
FT   DOMAIN          2..50
FT                   /note="F-box"
FT                   /evidence="ECO:0000259|PROSITE:PS50181"
SQ   SEQUENCE   1109 AA;  124727 MW;  5F87A9ABC96A8459 CRC64;
     MTLNIAELPS ETLVTIAGYL SNEDVRSFGR ALRSLHAFTA SKSFHRWQRL LGEFTSELDL
     TFDAIENDRK RQEKAIGPIS ASSYIFDVPE AQHFEDVCFP EVLYEMKITY SEHGQIQLDD
     IFTSLKTLGA STGLSSNPLV DCIDAAEGSR ILRAALEIVS PLQVVSSLIP LPISQQFEAM
     PLATADWIIL TAYLLFTKLQ PEQVLDLLPR YSKLGYVNQQ AIAEYFSYLL LFLRVYQFDS
     ALWLDVVRST KDQSTDRVRW SYANGSPLAA QSLQILRRRI EKWFVNYHEI QTIVSADPNA
     STLTNEQNLF VNTEIRKAEI FKVRAYAGTG KTKCLVDYAI RRPRKRILYV AYNKQAKLDA
     DFRFRKCNNV DCKTLHSVAF NALSVVNPVV NDQVQGRSTS QVQETGQPSS RRGTFNRIQS
     APVDDNFLRN WEIDPIVKAL GMTLDNVARV FTTPFEWQDE PSSWNPSFSS SAPTVGNAKS
     PKNVENLARV VATGITRFCQ SRDREPDVSH LSLGQCRTKL CNPELAIDWV KRFWKLIFDG
     KSTLMTHDCY LKMFSLTENA AADRMTFGKY DIVMFDEAQD ANPCMANIIL RQRDAAGIII
     IGDPYQMIYG FRGAKNECFD DGRLPPTKTF HLTRSFRFGQ EVADIANLIL GTVGERKPVR
     GVNTRVPSPA VFLPPLNPHK TVAPSDKHTV IFRSNTELVK YFFSSFAKDP TKATCLRTSA
     ANASSALIPL LRAGYFLYQG NKSKHPRLRG LASFEEAKTY LQREDKSGGM DTDEVDIQAV
     ALIVGMERYY AESKTGDGEF LKMLDSSAAC IVDVEAQADV VLTTAHQAKG LEWDDVIVAD
     DFVTHGLDAG NAMDQAWCKE ATNLLYVACT RARKRLQLSQ GISVFLLKRV GTFRFFVSPE
     PSNSSCPCCH GKQPFNTFLN EFLVASDNGR GTDTTGYFSS MPSICIGYET LMPRRDPAAT
     NGWTEHTRQP SNPFEIPKCV YLPTVACINC ILAWRTLTNK THGDIFRFAE GLKARLGFSK
     HLYHSDYDIF WAGRFPPNRA NLLSHHGVRR SLVDIYAPGM RMGFEKPQII GGINENDAAW
     DEFVFNQARD AGVEYDDEDV DEFIMGFEE
//