ID S8B0W1_PENO1 Unreviewed; 802 AA.
AC S8B0W1;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Metallo-beta-lactamase domain-containing protein {ECO:0000259|Pfam:PF12706};
GN ORFNames=PDE_02912 {ECO:0000313|EMBL:EPS27967.1};
OS Penicillium oxalicum (strain 114-2 / CGMCC 5302) (Penicillium decumbens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=933388 {ECO:0000313|EMBL:EPS27967.1, ECO:0000313|Proteomes:UP000019376};
RN [1] {ECO:0000313|EMBL:EPS27967.1, ECO:0000313|Proteomes:UP000019376}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=114-2 / CGMCC 5302 {ECO:0000313|Proteomes:UP000019376};
RX PubMed=23383313; DOI=10.1371/journal.pone.0055185;
RA Liu G., Zhang L., Wei X., Zou G., Qin Y., Ma L., Li J., Zheng H., Wang S.,
RA Wang C., Xun L., Zhao G.-P., Zhou Z., Qu Y.;
RT "Genomic and secretomic analyses reveal unique features of the
RT lignocellulolytic enzyme system of Penicillium decumbens.";
RL PLoS ONE 8:E55185-E55185(2013).
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DR EMBL; KB644410; EPS27967.1; -; Genomic_DNA.
DR AlphaFoldDB; S8B0W1; -.
DR STRING; 933388.S8B0W1; -.
DR eggNOG; KOG1361; Eukaryota.
DR HOGENOM; CLU_013294_1_1_1; -.
DR OrthoDB; 23465at2759; -.
DR PhylomeDB; S8B0W1; -.
DR Proteomes; UP000019376; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR23240; DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED; 1.
DR PANTHER; PTHR23240:SF39; REPAIR PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G04570)-RELATED; 1.
DR Pfam; PF12706; Lactamase_B_2; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000019376}.
FT DOMAIN 27..145
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF12706"
FT REGION 521..601
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 642..709
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 642..656
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 657..687
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 802 AA; 89673 MW; D1E888BE883248D0 CRC64;
MSTFNGVVEE FPDIQIDYFR KSDDRSPPLA CFLTHVHTDH LQGLESFRAP FIYCSRVTRE
VLLRLEKFPS RVNFAKGIIE SRRVHYHHLT TLLRPIPLNT PTVIELSPVK SIRVTLIDAN
HCPGSVMFLV EGGGKTILYT GDIRAEKWWV DSIVRNPFLV PWTLGGRQLD KIYLDTTYLG
PIGLPLGNFL PKAEAIADLL KTIQTYPPET VFHLEAWTFG YEEAWLALAA ALETEVHADL
YQRCIYQVLT CAKLDEGAPI GGFRLGNELH PGYLVQNYSQ GRIHVCVPPC PTAMKPGVVS
IRPVLKRQED EHDYSIPDVG AGGGAGDVQV QYVVELPEGL DPLAFVEGCL SRLNDLGGRF
QGMTEEARDK IKSRLLEEIG VNKGKITLNK FGVFLDDEEE TLALWELGDL LIERVHEYET
KKLKANMGMN PSSGMPERRV IQFPYARHSS YSELCDLLGV FMPRAIHACV VETWESWQSD
DLVHKFFGFL LENEELRALP FEARRAQMAV LRQDWAAEQA AEEEERLRSH SMPDSPLEFL
SNSTSSDNSE ATHDDKPESV HDNQPPVSGR NASEVSPAAS PVEEMDTDPR QPDEHPACPP
SAEEMLGEIE RAHSFLDDQD DVDLELGPLT RTLGLDGTFE SKVPELKAKE SKSAEEDEED
QGSDESEEED EDEEDEEEED DDEEASSENN TPPLPTRHES ARAARPAEVV SASLTAAGQG
SQMSVSESRA LSLPSTGSWR LTQERLQMLN LIRGVEVPAS QRRHARVAAY VAACADHYEE
WAAILPTSVR GHEGEEEEEE LL
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