ID S8CLZ9_9LAMI Unreviewed; 1245 AA.
AC S8CLZ9;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPS67765.1};
DE Flags: Fragment;
GN ORFNames=M569_07005 {ECO:0000313|EMBL:EPS67765.1};
OS Genlisea aurea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Lentibulariaceae; Genlisea.
OX NCBI_TaxID=192259 {ECO:0000313|EMBL:EPS67765.1, ECO:0000313|Proteomes:UP000015453};
RN [1] {ECO:0000313|EMBL:EPS67765.1, ECO:0000313|Proteomes:UP000015453}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23855885;
RA Leushkin E.V., Sutormin R.A., Nabieva E.R., Penin A.A., Kondrashov A.S.,
RA Logacheva M.D.;
RT "The miniature genome of a carnivorous plant Genlisea aurea contains a low
RT number of genes and short non-coding sequences.";
RL BMC Genomics 14:476-476(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00000600};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:13066;
CC Evidence={ECO:0000256|ARBA:ARBA00000600};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the DNA2/NAM7 helicase family.
CC {ECO:0000256|ARBA:ARBA00007913}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01341}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPS67765.1}.
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DR EMBL; AUSU01002938; EPS67765.1; -; Genomic_DNA.
DR AlphaFoldDB; S8CLZ9; -.
DR OrthoDB; 170190at2759; -.
DR Proteomes; UP000015453; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR CDD; cd21407; 1B_UPF1-like; 1.
DR CDD; cd18039; DEXXQc_UPF1; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR CDD; cd21400; ZBD_UPF1-like; 1.
DR Gene3D; 2.40.30.230; -; 1.
DR Gene3D; 6.10.140.1240; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR040812; UPF1_1B_dom.
DR InterPro; IPR018999; UPF1_CH/ZBD.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF364; REGULATOR OF NONSENSE TRANSCRIPTS 1; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF18141; UPF1_1B_dom; 1.
DR Pfam; PF09416; UPF1_Zn_bind; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51997; UPF1_CH_RICH; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU01341}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000015453};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU01341};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU01341}.
FT DOMAIN 142..301
FT /note="Upf1"
FT /evidence="ECO:0000259|PROSITE:PS51997"
FT DOMAIN 507..639
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT REGION 64..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 212..242
FT /note="C4"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01341"
FT REGION 961..1001
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1222..1245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..89
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EPS67765.1"
FT NON_TER 1245
FT /evidence="ECO:0000313|EMBL:EPS67765.1"
SQ SEQUENCE 1245 AA; 136217 MW; DEF4ABFF0BC1392A CRC64;
WPSCFRYGGI SPMDSQTSDL YETLSQPDTG NDAYTFIEFN TQGEEDFDYP EFQELSQPIR
SAASVWPPHT DSKSPSDVAS PSETTLGGSK TLGGVGGGVA HNGGGSNYSS KDAGVEESLT
AGMSGLNFED PVGDDDVFEY GKGDFKEHAC RYCGVTNPAC VIRCNIPSCR KWFCNSRGNT
SGSHIVNHLV RAKHKEVCLH KDSPLGETIL ECYNCGCRNV FLLGFISAKT DSVVVLLCRE
PCLSVGALKD MNWDLSQWCP LIDDRCFLQW LLKVPSEQEQ LKARQISAQQ INKIEELWKT
NPDATFEDLE KPGVDDEPEI VALKYEDAYQ YQNVFAPLIK LEADYDKMMK ESQSKDNITV
RWDVGLNKKC IAYFVFPKED NELRLVPGDE LRLRYSGDAA HSPWQSVGHV IKLTAQEEVV
LELSASQDIP VDVNHGFNVD FVWKSTSFDR MQGAMKTFAV DDTSVSGYIY HHLLGHEVEM
HLVRNALPRR FGAPGLPELN ASQVNAVKSV LQKPLSLIQG PPGTGKTVTS AAIVYHMAKQ
GQGQVLVCAP SNVAVDQLAE KISATGLKVV RLCAKSREAV SSPVEHLTLH YQVRHLDTSE
KSELHKLQQL KDEQGELSSS DEKKYKALKR STEREISQSA DVICCTCVGA GDPRLSNFRF
RQVLIDESTQ ATEPECLIPL VLGAKQVILV GDHCQLGPVI MCKKAARAGL AQSLFERLVL
LGVKPIRLQV QYRMHPSLSE FPSNNFYEGS LQNGVAVNER QLPGIDFPWP VPSRPMFFYV
QMGQEEISAS GTSYLNRTEA ANVEKIVTAF LKSGVVPTQI GVITPYEGQR AYIVNYMARI
GSLRQQLYKE IEVASVDSFQ GREKDYIILS CVRSNEHQGI GFLNDPRRLN VALTRARYGI
VLLGNPKVLS KQPLWNGLLS HYKENECLVE GPLNNLKQSM VQFQKPKKVY NDRRLLYGGS
PGIVPNDASG RGARSREMTK PSRGSFMPPG MPNGSHKPGT HPSGYPASRV PIPPYHEGPP
SQPYAIPSRT VVHGPVGTVP QVPQPGNQGF GSGRGNFTAP IGSHLPQQQG AQSGVGNLTS
NFNFSPIENA GGQTAVGGPL SQPGYVSTVV GQGSSLPYGD AFSMSGVSQD FLGDDFKSQG
SHVPYNEFSS QARLSGAYPL DYMTQGAQDV FPGSFLNQNP QAAGFGRFAA PGGDFMSQDY
SGHGAQGLFT QSAFNGQFQE ESSHNHFGLG GANPLQPQGI GMQPF
//
