ID S9TWR7_9TRYP Unreviewed; 776 AA.
AC S9TWR7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=EF-hand domain-containing family member C2 {ECO:0000256|ARBA:ARBA00039880};
GN ORFNames=STCU_08143 {ECO:0000313|EMBL:EPY22754.1}, STCU_08728
GN {ECO:0000313|EMBL:EPY21024.1};
OS Strigomonas culicis.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Strigomonadinae; Strigomonas.
OX NCBI_TaxID=28005 {ECO:0000313|EMBL:EPY21024.1, ECO:0000313|Proteomes:UP000015354};
RN [1] {ECO:0000313|EMBL:EPY21024.1, ECO:0000313|Proteomes:UP000015354}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23560078;
RA Motta M.C., Martins A.C., de Souza S.S., Catta-Preta C.M., Silva R.,
RA Klein C.C., de Almeida L.G., de Lima Cunha O., Ciapina L.P., Brocchi M.,
RA Colabardini A.C., de Araujo Lima B., Machado C.R., de Almeida Soares C.M.,
RA Probst C.M., de Menezes C.B., Thompson C.E., Bartholomeu D.C., Gradia D.F.,
RA Pavoni D.P., Grisard E.C., Fantinatti-Garboggini F., Marchini F.K.,
RA Rodrigues-Luiz G.F., Wagner G., Goldman G.H., Fietto J.L., Elias M.C.,
RA Goldman M.H., Sagot M.F., Pereira M., Stoco P.H., de Mendonca-Neto R.P.,
RA Teixeira S.M., Maciel T.E., de Oliveira Mendes T.A., Urmenyi T.P.,
RA de Souza W., Schenkman S., de Vasconcelos A.T.;
RT "Predicting the Proteins of Angomonas deanei, Strigomonas culicis and Their
RT Respective Endosymbionts Reveals New Aspects of the Trypanosomatidae
RT Family.";
RL PLoS ONE 8:E60209-E60209(2013).
RN [2] {ECO:0000313|EMBL:EPY21024.1}
RP NUCLEOTIDE SEQUENCE.
RA Motta M.C.M., Martins A.C.A., Preta C.M.C.C., Silva R., de Souza S.S.,
RA Klein C.C., de Almeida L.G.P., Cunha O.L., Colabardini A.C., Lima B.A.,
RA Machado C.R., Soares C.M.A., de Menezes C.B.A., Bartolomeu D.C.,
RA Grisard E.C., Fantinatti-Garboggini F., Rodrigues-Luiz G.F., Wagner G.,
RA Goldman G.H., Fietto J.L.R., Ciapina L.P., Brocchi M., Elias M.C.,
RA Goldman M.H.S., Sagot M.-F., Pereira M., Stoco P.H., Teixeira S.M.R.,
RA de Mendonca-Neto R.P., Maciel T.E.F., Mendes T.A.O., Urmenyi T.P.,
RA Teixeira M.M.G., de Camargo E.F.P., de Sousa W., Schenkman S.,
RA de Vasconcelos A.T.R.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated
CC doublet microtubules (DMTs) in cilia axoneme, which is required for
CC motile cilia beating. {ECO:0000256|ARBA:ARBA00035003}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC {ECO:0000256|ARBA:ARBA00004430}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPY21024.1}.
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DR EMBL; ATMH01008728; EPY21024.1; -; Genomic_DNA.
DR EMBL; ATMH01008143; EPY22754.1; -; Genomic_DNA.
DR AlphaFoldDB; S9TWR7; -.
DR EnsemblProtists; EPY21024; EPY21024; STCU_08728.
DR EnsemblProtists; EPY22754; EPY22754; STCU_08143.
DR OrthoDB; 124589at2759; -.
DR Proteomes; UP000015354; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
DR Gene3D; 2.30.29.170; -; 3.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR006602; DM10_dom.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR040193; EFHC1/EFHC2/EFHB.
DR PANTHER; PTHR12086; EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12086:SF11; EF-HAND DOMAIN-CONTAINING FAMILY MEMBER C2; 1.
DR Pfam; PF06565; DM10_dom; 3.
DR SMART; SM00676; DM10; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS51336; DM10; 3.
PE 4: Predicted;
KW Cell projection {ECO:0000313|EMBL:EPY21024.1};
KW Cilium {ECO:0000313|EMBL:EPY21024.1};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Flagellum {ECO:0000313|EMBL:EPY21024.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000015354}.
FT DOMAIN 101..208
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT DOMAIN 277..396
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT DOMAIN 457..561
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 776 AA; 89041 MW; 923402302299E126 CRC64;
MKNSTARTQP EKRFEHLPSD DNRPLAIGAN FQDDPLNRNT LRKSHALQLD RKTDYAPHTE
YTYTAFDGDK TRSSRKPLED INDVDVWNGW FSEEISEEDK KYFVARFAGF FKETVQNSTM
EKERVRKVCI RFHVEDNSIS IQESQEINSG ITDTRILDRR QVPKDTRNPS NIFLLSDFQI
GGSVTIYGII YTIVDMDARS RKYAREVLGE EAPAAVPWPD DVYSASVKNT FSKSAVRGVT
SDDMDLRRAV EQQLAGIYSK HSNEDITIAR QFFKNPIKEH LSYLALWDDR ANISGDLHFC
VIRLYSENTS IEIVEDRPEN CGSTGGPILL SRQRVPKPGS DLAASRFQEH TYGKLMKNNY
LSAEDIHIGE TYTIYGKPFF VYDCDQFTRD YVKANCGFSL EPAIDIKPFL SEQKNHKVMF
YPPPPNGFGS ETEKRDNWLT LEGKTARIDL EKVIHETGRV MKFSAKFAKP LSKDDEGRRF
LVAFYRETDE VEVTEKAIRN SGFMGGRFLT KGKHRMELPN GTTRPYTPSD FQVGKEVVIF
KRPFLLLEMD DMTQHIVNGT DNPTNEDKMR YLLLLLKQQI SLKFKKANEA YRSLAPQGTL
GYQQVKEFLR SCSCTISDEE AVLLVQNIAP GSNGIISYDQ FLEIVNAGIE NMDEASLSAR
SVKNVNMTIN TTMKDTASVS EIKHRHRQLR KSLQHKLIQR KGTVQEQFRL LADHSANSRL
NRDTFRKSLN EVMHFNVNKP DEDMLVSMLF DGQQDENGDI TFKQFQEFID YCDDLS
//
