ID   S9U2E2_9TRYP            Unreviewed;       592 AA.
AC   S9U2E2;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Thyroid hormone receptor interactor 4 {ECO:0000313|EMBL:EPY24962.1};
GN   ORFNames=STCU_06917 {ECO:0000313|EMBL:EPY24962.1};
OS   Strigomonas culicis.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Strigomonadinae; Strigomonas.
OX   NCBI_TaxID=28005 {ECO:0000313|EMBL:EPY24962.1, ECO:0000313|Proteomes:UP000015354};
RN   [1] {ECO:0000313|EMBL:EPY24962.1, ECO:0000313|Proteomes:UP000015354}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23560078;
RA   Motta M.C., Martins A.C., de Souza S.S., Catta-Preta C.M., Silva R.,
RA   Klein C.C., de Almeida L.G., de Lima Cunha O., Ciapina L.P., Brocchi M.,
RA   Colabardini A.C., de Araujo Lima B., Machado C.R., de Almeida Soares C.M.,
RA   Probst C.M., de Menezes C.B., Thompson C.E., Bartholomeu D.C., Gradia D.F.,
RA   Pavoni D.P., Grisard E.C., Fantinatti-Garboggini F., Marchini F.K.,
RA   Rodrigues-Luiz G.F., Wagner G., Goldman G.H., Fietto J.L., Elias M.C.,
RA   Goldman M.H., Sagot M.F., Pereira M., Stoco P.H., de Mendonca-Neto R.P.,
RA   Teixeira S.M., Maciel T.E., de Oliveira Mendes T.A., Urmenyi T.P.,
RA   de Souza W., Schenkman S., de Vasconcelos A.T.;
RT   "Predicting the Proteins of Angomonas deanei, Strigomonas culicis and Their
RT   Respective Endosymbionts Reveals New Aspects of the Trypanosomatidae
RT   Family.";
RL   PLoS ONE 8:E60209-E60209(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPY24962.1}.
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DR   EMBL; ATMH01006917; EPY24962.1; -; Genomic_DNA.
DR   AlphaFoldDB; S9U2E2; -.
DR   EnsemblProtists; EPY24962; EPY24962; STCU_06917.
DR   OrthoDB; 198336at2759; -.
DR   Proteomes; UP000015354; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd06554; ASCH_ASC-1_like; 1.
DR   Gene3D; 2.30.130.30; Hypothetical protein; 1.
DR   InterPro; IPR007374; ASCH_domain.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR039128; TRIP4-like.
DR   InterPro; IPR009349; Znf_C2HC5.
DR   PANTHER; PTHR12963:SF0; EXPRESSED PROTEIN; 1.
DR   PANTHER; PTHR12963; THYROID RECEPTOR INTERACTING PROTEIN RELATED; 1.
DR   Pfam; PF04266; ASCH; 1.
DR   Pfam; PF06221; zf-C2HC5; 1.
DR   SUPFAM; SSF88697; PUA domain-like; 1.
PE   4: Predicted;
KW   Receptor {ECO:0000313|EMBL:EPY24962.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015354}.
FT   DOMAIN          136..170
FT                   /note="Zinc finger C2HC5-type"
FT                   /evidence="ECO:0000259|Pfam:PF06221"
FT   DOMAIN          453..548
FT                   /note="ASCH"
FT                   /evidence="ECO:0000259|Pfam:PF04266"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          288..317
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          334..363
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   592 AA;  66119 MW;  AD7F0E297B62356F CRC64;
     MPPKKWARVP TPGQHESSTE SPEQYIYKTI KDSNNLGLEE QEIKGMTGVL VNCKTRKEIF
     EWSTSLMLDE EFAAEVIKRR VDVGPPFEGE TVVAKAPVKK AGHLKTTKGK KRDMSLNEFQ
     KKKDTAAAAL KAGLFECGCF ATIHNLKGNC GNCGRIICEQ ESDDKCYFCG FEPERCIAYE
     IAVQEGKISE AAQSQNKESY EAAIERRDRL LEYAENRAKR TTVIDDQSAS LFAPQNAWIS
     AEERREAERT PLRRAPERIE AKHRGAHEMH LQFVNSNLAL GARERDAGVV TDEAKQQAAV
     ANESSSEGEG DSGEDAAEQR GVAPLPTLLQ SIWYNPDGSP EVDKKQQTAP SFAAGGDTQA
     PALGRPVQAV KEVSKRVQQN YFEDDVSLFV EELRGEAAKE LLFNADFVHD NSEDDDVLGD
     DKASPLTVAP KANLAVRFPP TRVMRAKDEG VCLSMHQPWA SMLVAGIKTH EGRVWDTDYR
     GKLWIHAASA QPVDIKETES HYSQFMSPDQ TFPKHYPCRV LLGYVYLTEC LDRESYEAAF
     TPAERQEGCP FSFICVEPKQ LPFPLPMNGN HKLFKLDHKV HIAAKKQLQE IV
//