ID S9UYH5_9TRYP Unreviewed; 337 AA.
AC S9UYH5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase-like protein {ECO:0000313|EMBL:EPY33799.1};
GN ORFNames=STCU_01967 {ECO:0000313|EMBL:EPY33799.1};
OS Strigomonas culicis.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Strigomonadinae; Strigomonas.
OX NCBI_TaxID=28005 {ECO:0000313|EMBL:EPY33799.1, ECO:0000313|Proteomes:UP000015354};
RN [1] {ECO:0000313|EMBL:EPY33799.1, ECO:0000313|Proteomes:UP000015354}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23560078;
RA Motta M.C., Martins A.C., de Souza S.S., Catta-Preta C.M., Silva R.,
RA Klein C.C., de Almeida L.G., de Lima Cunha O., Ciapina L.P., Brocchi M.,
RA Colabardini A.C., de Araujo Lima B., Machado C.R., de Almeida Soares C.M.,
RA Probst C.M., de Menezes C.B., Thompson C.E., Bartholomeu D.C., Gradia D.F.,
RA Pavoni D.P., Grisard E.C., Fantinatti-Garboggini F., Marchini F.K.,
RA Rodrigues-Luiz G.F., Wagner G., Goldman G.H., Fietto J.L., Elias M.C.,
RA Goldman M.H., Sagot M.F., Pereira M., Stoco P.H., de Mendonca-Neto R.P.,
RA Teixeira S.M., Maciel T.E., de Oliveira Mendes T.A., Urmenyi T.P.,
RA de Souza W., Schenkman S., de Vasconcelos A.T.;
RT "Predicting the Proteins of Angomonas deanei, Strigomonas culicis and Their
RT Respective Endosymbionts Reveals New Aspects of the Trypanosomatidae
RT Family.";
RL PLoS ONE 8:E60209-E60209(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPY33799.1}.
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DR EMBL; ATMH01001967; EPY33799.1; -; Genomic_DNA.
DR AlphaFoldDB; S9UYH5; -.
DR EnsemblProtists; EPY33799; EPY33799; STCU_01967.
DR OrthoDB; 1327616at2759; -.
DR Proteomes; UP000015354; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR CDD; cd05300; 2-Hacid_dh_1; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43333:SF1; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000015354}.
FT DOMAIN 133..299
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 337 AA; 37378 MW; 312D2270132626FD CRC64;
MSITVCAYVV RPSIDLVSNF LRANLGAKAK DIVVGNSVDE FAAAKAAGGP IALIVENTAH
DTLKSLCDDF DKSSDRRVKF IYSASAGVDA YRLHELKPEL KGIPFHNAQG VYSRVLAEHV
AFSMLYFNRY PWRLIQLKRE KKWDRFNMTE VHGQKVAIMG YGDIGQQCGK LAAGLGMQVT
GIRRRAPETP IDEYGVHVKT EAETDAVVAE ADFVVGVLPG TSTTRHYFNK DFFRKMKPSA
VFINIGRGMT QHEEDVCEAL KNGTIRGAAL DVFETEPPSQ TSPLWDLPDD KLLLSAHCAG
YTNRMVENSL VNFIEIFESY NTTGTSDAHR ICIDQGY
//
