ID S9VBG9_9TRYP Unreviewed; 545 AA.
AC S9VBG9;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Folate/biopterin transporter {ECO:0000313|EMBL:EPY24381.1};
GN ORFNames=STCU_07209 {ECO:0000313|EMBL:EPY24381.1};
OS Strigomonas culicis.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Strigomonadinae; Strigomonas.
OX NCBI_TaxID=28005 {ECO:0000313|EMBL:EPY24381.1, ECO:0000313|Proteomes:UP000015354};
RN [1] {ECO:0000313|EMBL:EPY24381.1, ECO:0000313|Proteomes:UP000015354}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23560078;
RA Motta M.C., Martins A.C., de Souza S.S., Catta-Preta C.M., Silva R.,
RA Klein C.C., de Almeida L.G., de Lima Cunha O., Ciapina L.P., Brocchi M.,
RA Colabardini A.C., de Araujo Lima B., Machado C.R., de Almeida Soares C.M.,
RA Probst C.M., de Menezes C.B., Thompson C.E., Bartholomeu D.C., Gradia D.F.,
RA Pavoni D.P., Grisard E.C., Fantinatti-Garboggini F., Marchini F.K.,
RA Rodrigues-Luiz G.F., Wagner G., Goldman G.H., Fietto J.L., Elias M.C.,
RA Goldman M.H., Sagot M.F., Pereira M., Stoco P.H., de Mendonca-Neto R.P.,
RA Teixeira S.M., Maciel T.E., de Oliveira Mendes T.A., Urmenyi T.P.,
RA de Souza W., Schenkman S., de Vasconcelos A.T.;
RT "Predicting the Proteins of Angomonas deanei, Strigomonas culicis and Their
RT Respective Endosymbionts Reveals New Aspects of the Trypanosomatidae
RT Family.";
RL PLoS ONE 8:E60209-E60209(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Folate-
CC biopterin transporter (TC 2.A.71) family.
CC {ECO:0000256|ARBA:ARBA00007015}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPY24381.1}.
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DR EMBL; ATMH01007209; EPY24381.1; -; Genomic_DNA.
DR AlphaFoldDB; S9VBG9; -.
DR EnsemblProtists; EPY24381; EPY24381; STCU_07209.
DR OrthoDB; 162667at2759; -.
DR Proteomes; UP000015354; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR039309; BT1.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR31585; FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR31585:SF0; FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC; 1.
DR Pfam; PF03092; BT1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015354};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 88..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..521
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 545 AA; 59583 MW; 7F075767BA2741D7 CRC64;
MNRVLSSDEL MTRTANEKHA CVDVPLPQLL EQGAIPSAAT GKASRRAREG TSGVFYSTVG
GTDEEAAVLG VHPLEEPVPH YAAPAPPLMV LVLLLLSALA QGFSSTALTF FIRQDLGFDP
VHEMRYWAYV GIMAFFQPVL GWVSDVFVVC GEKRRPLFIL CVGVNTAIFF FYYLFPKVTA
DYRVFLCLSL LSQCMTMGTY IPLNGILVEV GRHDAETAEQ STARLGAIMS VAMVWRSVGS
LGASLLHLLL VRVCSNRSLL LVVCIQLTLV ILVMLWVPTA LFAPGSAPQH HVVQRVRAGW
GQFRRSCNPR NLRSDGFVFF FVLCFVFVYT TMPDGSTSYM NYTFSAFSLS SGVLSLSSTC
GSIGSIVGAY VFSVWMKRRA AQEERGKTPT SMFTIFFLGS VAWAFGYVTN LLLCTGFVTD
VLHIAPAVYI PVDSFFVSMF VRFAFMPTLT MAAEHAPKHL EATTFEVFSV VCIVGGTCSA
LLTSVIAEAL GITKENYGPL STLIVLSIIC KLLPIPIAYI LPKRDAAEES TDVVVEREEV
VDGEA
//
