ID S9VQR1_9TRYP Unreviewed; 148 AA.
AC S9VQR1;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=E2 ubiquitin-conjugating enzyme {ECO:0000256|ARBA:ARBA00012486};
DE EC=2.3.2.23 {ECO:0000256|ARBA:ARBA00012486};
GN ORFNames=ADEAN_000196700 {ECO:0000313|EMBL:CAD2214520.1};
OS Angomonas deanei.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Strigomonadinae; Angomonas.
OX NCBI_TaxID=59799 {ECO:0000313|EMBL:CAD2214520.1, ECO:0000313|Proteomes:UP000515908};
RN [1] {ECO:0000313|EMBL:CAD2214520.1, ECO:0000313|Proteomes:UP000515908}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Crithidia deanei Carvalho (ATCC PRA-265)
RC {ECO:0000313|Proteomes:UP000515908};
RA Newling K., Davey J., Forrester S.;
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family.
CC {ECO:0000256|RuleBase:RU362109}.
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DR EMBL; LR877147; CAD2214520.1; -; Genomic_DNA.
DR AlphaFoldDB; S9VQR1; -.
DR EnsemblProtists; EPY42293; EPY42293; AGDE_01630.
DR EnsemblProtists; EPY43194; EPY43194; AGDE_00728.
DR VEuPathDB; TriTrypDB:ADEAN_000196700; -.
DR OrthoDB; 5478564at2759; -.
DR Proteomes; UP000515908; Chromosome 03.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:UniProt.
DR CDD; cd00195; UBCc; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR000608; UBQ-conjugat_E2.
DR InterPro; IPR023313; UBQ-conjugating_AS.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR PANTHER; PTHR24068; UBIQUITIN-CONJUGATING ENZYME E2; 1.
DR PANTHER; PTHR24068:SF74; UBIQUITIN-CONJUGATING ENZYME E2-17 KDA; 1.
DR Pfam; PF00179; UQ_con; 1.
DR SMART; SM00212; UBCc; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS00183; UBC_1; 1.
DR PROSITE; PS50127; UBC_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU362109};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362109};
KW Reference proteome {ECO:0000313|Proteomes:UP000515908};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|RuleBase:RU362109}.
FT DOMAIN 1..148
FT /note="UBC core"
FT /evidence="ECO:0000259|PROSITE:PS50127"
FT ACT_SITE 86
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10133"
SQ SEQUENCE 148 AA; 16704 MW; 26946D3B7209397F CRC64;
MALRRIQKEL KDLEKDPPAN TSGGPTNDND LFNWKATIIG PEESPYAGGL FFLNIHFPSD
YPFKPPKLQF VTKIYHPNIN NNGGICLDIL KDQWSPALTI SKVLLSVCSL LTDPNPEDPL
VPDIARQYKT DRASFNKTAQ EWTRLYAT
//
