ID S9VXH5_SCHCR Unreviewed; 539 AA.
AC S9VXH5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Adaptin {ECO:0000313|EMBL:EPY50700.1};
GN ORFNames=SPOG_00758 {ECO:0000313|EMBL:EPY50700.1};
OS Schizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 /
OS NBRC 106824 / NRRL Y48691) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=653667 {ECO:0000313|EMBL:EPY50700.1, ECO:0000313|Proteomes:UP000015464};
RN [1] {ECO:0000313|EMBL:EPY50700.1, ECO:0000313|Proteomes:UP000015464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 / NRRL Y48691
RC {ECO:0000313|Proteomes:UP000015464};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
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DR EMBL; KE546992; EPY50700.1; -; Genomic_DNA.
DR RefSeq; XP_013024389.1; XM_013168935.1.
DR AlphaFoldDB; S9VXH5; -.
DR STRING; 653667.S9VXH5; -.
DR EnsemblFungi; EPY50700; EPY50700; SPOG_00758.
DR GeneID; 25035090; -.
DR eggNOG; KOG1087; Eukaryota.
DR HOGENOM; CLU_017092_0_0_1; -.
DR OMA; VNDRNPT; -.
DR OrthoDB; 460229at2759; -.
DR Proteomes; UP000015464; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0099638; P:endosome to plasma membrane protein transport; IEA:EnsemblFungi.
DR GO; GO:0006895; P:Golgi to endosome transport; IEA:EnsemblFungi.
DR GO; GO:0006896; P:Golgi to vacuole transport; IEA:EnsemblFungi.
DR CDD; cd14235; GAT_GGA_fungi; 1.
DR CDD; cd16998; VHS_GGA_fungi; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 2.60.40.1230; -; 1.
DR InterPro; IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
DR InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR008153; GAE_dom.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR47180; ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED; 1.
DR PANTHER; PTHR47180:SF1; ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED; 1.
DR Pfam; PF02883; Alpha_adaptinC2; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00809; Alpha_adaptinC2; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF49348; Clathrin adaptor appendage domain; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50180; GAE; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 4: Predicted;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000015464};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 15..151
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 178..305
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT DOMAIN 422..539
FT /note="GAE"
FT /evidence="ECO:0000259|PROSITE:PS50180"
SQ SEQUENCE 539 AA; 60832 MW; 3AE248A46B40E38E CRC64;
MSSAKRKLYR LIQNATEPFT FEPDLALNLD ITDLINQAQG NIPREAAFAI VRKVNDRNPT
VAYLALNLLD ICVKNCGYAF HLQIATKEFL NEFVRRFPER PPSRLNKIQV MILSLIEEWR
RTICRTDRYH EDLGFIRDMH RLLSYKGYTF PEIAKDNLAV LSQKSVLKTA EELEKEDRDA
MSAKLQEHIR RGTPHDLMEA NKLMKIMAGF DSEHKRRYKE HVLVELEKVK RKASLFGEML
NEITEADKLS SGDLYEELAY SLKAAVIKVD KILEELDSSD DYYNSVIDLK SLIIALLSQY
DHLLKGDFHS AQNTSTNAHA LLQSTSNLSK DTNANSRVSS APASQSAMDL LIDLDVGSSQ
QSDTSNVQIP SMKKSNPLFD LSAGVPKSLD RTETPPAVGA ISLSDNFSNM SLLSHQADSP
NTTVSPTTVF SNEHVRFQLA PKKVSDGRFV ILATYSNSNF SESIENLQSF IALPKKYSLE
LNPQYGTRLS PLQQNGIHQE MFVSNVSTDT TELPIRFKLT YYVKNVQQEH IGQSTVKLT
//
