ID S9VY75_SCHCR Unreviewed; 663 AA.
AC S9VY75;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=RhoGAP {ECO:0000313|EMBL:EPY52593.1};
GN ORFNames=SPOG_01915 {ECO:0000313|EMBL:EPY52593.1};
OS Schizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 /
OS NBRC 106824 / NRRL Y48691) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=653667 {ECO:0000313|EMBL:EPY52593.1, ECO:0000313|Proteomes:UP000015464};
RN [1] {ECO:0000313|EMBL:EPY52593.1, ECO:0000313|Proteomes:UP000015464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 / NRRL Y48691
RC {ECO:0000313|Proteomes:UP000015464};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
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DR EMBL; KE546989; EPY52593.1; -; Genomic_DNA.
DR RefSeq; XP_013022473.1; XM_013167019.1.
DR AlphaFoldDB; S9VY75; -.
DR STRING; 653667.S9VY75; -.
DR EnsemblFungi; EPY52593; EPY52593; SPOG_01915.
DR GeneID; 25036239; -.
DR eggNOG; ENOG502QQWB; Eukaryota.
DR HOGENOM; CLU_416283_0_0_1; -.
DR OMA; REDYFCE; -.
DR OrthoDB; 1328399at2759; -.
DR Proteomes; UP000015464; Unassembled WGS sequence.
DR GO; GO:0005938; C:cell cortex; IEA:UniProt.
DR GO; GO:0032153; C:cell division site; IEA:UniProt.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR23065:SF17; RHO-GTPASE-ACTIVATING PROTEIN RGD2; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015464}.
FT DOMAIN 421..614
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 151..179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 632..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..178
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 632..653
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 663 AA; 75886 MW; 275B2FCC56FB8F34 CRC64;
MTAMWDGFAD SFWTRDYITG VKSAQELINQ GIEQNKSLLS LLQAKSKALI ACSDILVKAC
AKHDKQYPFS HDTNILLTSA AINELREDYF CEASLQKKWS EQLEYLVIGP FEKWNKNYAK
RVGSLSSTIQ VKIENYNSRL LHVQRLKSSL LNPKQRGHRK SSSLSSINSR TQGSNKKLES
EMPFILAGKN YSNDEFSKFL STLKKTMNKV SNSQPAEYVT HDVDFQKALS YTLPGSEKSK
LEQMTDELAA LDMVNVKERT DKSVGTPNSN VQLTQKAINL INTNQEDSLD SSSFFSTQNE
NKPVSFSNDL DKYYLAFSNL EQSRIELEQY LFTYYKELEK CEIDRLSAIE TILADHSGCF
SSFTTRLESV VSNQTKTTRS LDKLQDLSNQ VKRYYTGYFT SVSNADLFLQ NGYESPIKSY
SFLDTQISRV VPEVLMYLVD GYSYIKDFDA LYTIWTKEVP LKKAYELKSI LLNNAIIDVV
PILEKYPLHT IAFSLKLCLL EFSDSLIRSS FYDYFNALYS TYTEDKDIEH RVYSIRQCLL
HLHSTPLRLL EDLISHFKFF ADSAQFSRDD LYKIAKIIAP CILRPPKNVT RISVEDTHPV
SLVLDLLQEF KQLFGNLERS VTPPIEMERA LTPINTSPTK LKSSRSSSPI KLPSPTKLFR
PFS
//
