ID S9VZK6_SCHCR Unreviewed; 1230 AA.
AC S9VZK6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};
GN ORFNames=SPOG_00064 {ECO:0000313|EMBL:EPY51639.1};
OS Schizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 /
OS NBRC 106824 / NRRL Y48691) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=653667 {ECO:0000313|EMBL:EPY51639.1, ECO:0000313|Proteomes:UP000015464};
RN [1] {ECO:0000313|EMBL:EPY51639.1, ECO:0000313|Proteomes:UP000015464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 / NRRL Y48691
RC {ECO:0000313|Proteomes:UP000015464};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR005719}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC1 subfamily.
CC {ECO:0000256|ARBA:ARBA00005597}.
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DR EMBL; KE546990; EPY51639.1; -; Genomic_DNA.
DR RefSeq; XP_013023025.1; XM_013167571.1.
DR AlphaFoldDB; S9VZK6; -.
DR STRING; 653667.S9VZK6; -.
DR EnsemblFungi; EPY51639; EPY51639; SPOG_00064.
DR GeneID; 25034396; -.
DR eggNOG; KOG0018; Eukaryota.
DR HOGENOM; CLU_001042_0_1_1; -.
DR OMA; SYIRDHT; -.
DR OrthoDB; 231904at2759; -.
DR Proteomes; UP000015464; Unassembled WGS sequence.
DR GO; GO:0000779; C:condensed chromosome, centromeric region; IEA:EnsemblFungi.
DR GO; GO:0030892; C:mitotic cohesin complex; IEA:EnsemblFungi.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0061776; F:topological DNA co-entrapment activity; IEA:EnsemblFungi.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0140588; P:chromatin looping; IEA:EnsemblFungi.
DR GO; GO:0007064; P:mitotic sister chromatid cohesion; IEA:EnsemblFungi.
DR CDD; cd03275; ABC_SMC1_euk; 2.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR028468; Smc1_ABC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR PANTHER; PTHR18937:SF12; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN; 1.
DR PANTHER; PTHR18937; STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR005719};
KW Reference proteome {ECO:0000313|Proteomes:UP000015464}.
FT DOMAIN 521..637
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT COILED 200..227
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 344..371
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 402..475
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 678..774
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 841..924
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1230 AA; 141534 MW; 4ED339B3841EE2FB CRC64;
MGRLLRLEVE NFKSYRGRQT IGPFEDFTSV IGPNGSGKSN LMDAISFVLG VKSSHLRSSN
IRELIYRGRV MSSQGSTSFD DSQSPRSAYV KLVYELDDGE EREYKRVITP NGSAEYKIND
QPAQFSEYCK SLEDQNILVR ARNFLVFQGD VEAIASQSPV DLSRLIEQIC GSLEFKGDYE
KYKQEQDYAV NLSAHSFNKK RGINAEIKQY QEQKAEAELY ESKKEQRDIA SLIFLLWKLY
HIEKNVHFNT KDIKKIQNST RELAKRQEAS SAKVESLREQ EGAIHRQLLL FDRNVRKQEK
FIASKRPELI SLAEKASEST VNLQKIQRKV GEVEKDYTSQ SSTLQMLENQ LASLNAAEEQ
LIRNIHEREK QRIQKLSPED QKEYDDLRTQ ADLQNSKTLT ELQSLNRKIK VASQARNALA
EVVEDLKMRK TQSKEKIHNL TEEKDALITE VNRRIDELES ARQSIQQKRA NYSHLCQQER
DLNDELHVCL QKLLEANADR NESNQDIKKR EALYAIKRIY PGIKGRVIDL CSPTQKKYES
ALVAALGRNF DAIVVESQAT AKECIEYIRE QRIGVMTFLP MDTIAVKPIN QSFRGTHAGA
RLAIDVVNFE PQYERVVVSA LGNTLICDNL NVARDLSYNK RANAKTVTLE GTVIHKTGLI
TGGSSSTRSA KHWDDREIEQ LKQNQNDLIS RIDKIQTEKA ASLVVEQDTI NIHNLESELS
LMKESLNAKL RSLEDKRKES DHFNELYRQK KPELESSERE LSEMEEYQSE LLQQTHEIED
KIFFNFCKRT KITNIRSYEE LQRSFTQQYS QKQLEFANQK ALLENRLGFE RQRTSDIELR
LNRLKEFIRK DELSIKEYEQ KHEVLETEVA TAEAELDLLK EESAETKSKN EEVLRTISQH
KLENKRFLAE ITKLRNDVTL AESEIERFAS DWHAIVRKCK LEDIPLPLSE GSLSNIPIDE
FGQNVDTMDI DSDPKTVQAA FGKFGIEVDY EELDDELKGD GSESMGTVLQ EKLREYDEEL
ERMSPNMKAM ERLEVVEQRL SRLDDEFGEV RKSAKTAKER FNSVKEQRLK KFQEAFNHIS
EQIDPIYKEL TKSPAFPLGG TAYLTLDDSD EPYLGGIRFH AMPPMKRFRD MDQLSGGEKT
MAALALLFAI HSYQPSPFFV LDEIDAALDQ TNVSKIANYI RQHASNGFQF VVISLKNQLF
SKSEALVGIY RDQEQNSSKT LSINLEAYAQ
//
