ID S9W3U6_SCHCR Unreviewed; 622 AA.
AC S9W3U6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Transcription factor Hsf1 {ECO:0000313|EMBL:EPY52620.1};
GN ORFNames=SPOG_01941 {ECO:0000313|EMBL:EPY52620.1};
OS Schizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 /
OS NBRC 106824 / NRRL Y48691) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=653667 {ECO:0000313|EMBL:EPY52620.1, ECO:0000313|Proteomes:UP000015464};
RN [1] {ECO:0000313|EMBL:EPY52620.1, ECO:0000313|Proteomes:UP000015464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 / NRRL Y48691
RC {ECO:0000313|Proteomes:UP000015464};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HSF family. {ECO:0000256|RuleBase:RU004020}.
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DR EMBL; KE546989; EPY52620.1; -; Genomic_DNA.
DR RefSeq; XP_013022499.1; XM_013167045.1.
DR AlphaFoldDB; S9W3U6; -.
DR STRING; 653667.S9W3U6; -.
DR EnsemblFungi; EPY52620; EPY52620; SPOG_01941.
DR GeneID; 25036265; -.
DR eggNOG; KOG0627; Eukaryota.
DR HOGENOM; CLU_443554_0_0_1; -.
DR OMA; FANPNFQ; -.
DR OrthoDB; 1117127at2759; -.
DR Proteomes; UP000015464; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IEA:EnsemblFungi.
DR GO; GO:0005737; C:cytoplasm; IEA:EnsemblFungi.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:EnsemblFungi.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:EnsemblFungi.
DR GO; GO:0034605; P:cellular response to heat; IEA:EnsemblFungi.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000232; HSF_DNA-bd.
DR InterPro; IPR027725; HSF_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10015:SF206; HEAT SHOCK FACTOR PROTEIN; 1.
DR PANTHER; PTHR10015; HEAT SHOCK TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00447; HSF_DNA-bind; 1.
DR PRINTS; PR00056; HSFDOMAIN.
DR SMART; SM00415; HSF; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00434; HSF_DOMAIN; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000015464}.
FT DOMAIN 96..120
FT /note="HSF-type DNA-binding"
FT /evidence="ECO:0000259|PROSITE:PS00434"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 260..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 358..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 578..622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..329
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..594
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 622 AA; 68565 MW; 678A066514492933 CRC64;
MIQTASSVIG NNNNGANQMV DMSNSPGSET PVANANALTP VGTGSNSGSQ TRKITQFSNK
LYNMVNDSST DSLIRWSERG DSFFVIGHED FAKLVLPRYF KHNNFSSFVR QLNMYGFHKV
PHIQQGVLQS DSPNELLEFA NPNFQRDQPE LLCYVTRKKG GSQVSDDASN SLDMSTITME
LQNIRNQQLS LSSELSRIQV DNAALWQENI ETRERQRRHQ ETIDKILRFL ASVYLDGKQN
PPSKVMPRSR RLLLEAKYPS VSNPNLNANS NANRTSSFDA SPNSSATNAK FSPLGKHRES
DSDMRFRSMS AGPASSSYVS TAKSETGSPQ IVDTHNFMNE FNPQRKNSTE SLANPVDTGI
SPHHSPANEI PPSSNQEDTL ETKLSNTGDI INMLDDAGTV DNESMNTLSP LLFDYQDSGY
PPHADTAEES QMPVYGTQND NYTAAENNVP NRSALNPYSY NDYLSNVNPP YLPQPSKDQL
INYYPGYSDD QKRIANVSDG ITKQDQNIQA LADILGIPLS DVRGDPSGNP AFASSLNNNY
NLPLSSDLDS VLNVVPSEES FSESNPVFDE FTNISNLTSP PEISTNQSFD PNNIALPGLQ
KAHLNTPPPS QVRKKRKSSV GI
//
