ID S9W654_9TRYP Unreviewed; 748 AA.
AC S9W654;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=EF-hand domain-containing family member C2 {ECO:0000256|ARBA:ARBA00039880};
GN ORFNames=STCU_00515 {ECO:0000313|EMBL:EPY36570.1}, STCU_01406
GN {ECO:0000313|EMBL:EPY34696.1};
OS Strigomonas culicis.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Strigomonadinae; Strigomonas.
OX NCBI_TaxID=28005 {ECO:0000313|EMBL:EPY34696.1, ECO:0000313|Proteomes:UP000015354};
RN [1] {ECO:0000313|EMBL:EPY34696.1, ECO:0000313|Proteomes:UP000015354}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23560078;
RA Motta M.C., Martins A.C., de Souza S.S., Catta-Preta C.M., Silva R.,
RA Klein C.C., de Almeida L.G., de Lima Cunha O., Ciapina L.P., Brocchi M.,
RA Colabardini A.C., de Araujo Lima B., Machado C.R., de Almeida Soares C.M.,
RA Probst C.M., de Menezes C.B., Thompson C.E., Bartholomeu D.C., Gradia D.F.,
RA Pavoni D.P., Grisard E.C., Fantinatti-Garboggini F., Marchini F.K.,
RA Rodrigues-Luiz G.F., Wagner G., Goldman G.H., Fietto J.L., Elias M.C.,
RA Goldman M.H., Sagot M.F., Pereira M., Stoco P.H., de Mendonca-Neto R.P.,
RA Teixeira S.M., Maciel T.E., de Oliveira Mendes T.A., Urmenyi T.P.,
RA de Souza W., Schenkman S., de Vasconcelos A.T.;
RT "Predicting the Proteins of Angomonas deanei, Strigomonas culicis and Their
RT Respective Endosymbionts Reveals New Aspects of the Trypanosomatidae
RT Family.";
RL PLoS ONE 8:E60209-E60209(2013).
RN [2] {ECO:0000313|EMBL:EPY34696.1}
RP NUCLEOTIDE SEQUENCE.
RA Motta M.C.M., Martins A.C.A., Preta C.M.C.C., Silva R., de Souza S.S.,
RA Klein C.C., de Almeida L.G.P., Cunha O.L., Colabardini A.C., Lima B.A.,
RA Machado C.R., Soares C.M.A., de Menezes C.B.A., Bartolomeu D.C.,
RA Grisard E.C., Fantinatti-Garboggini F., Rodrigues-Luiz G.F., Wagner G.,
RA Goldman G.H., Fietto J.L.R., Ciapina L.P., Brocchi M., Elias M.C.,
RA Goldman M.H.S., Sagot M.-F., Pereira M., Stoco P.H., Teixeira S.M.R.,
RA de Mendonca-Neto R.P., Maciel T.E.F., Mendes T.A.O., Urmenyi T.P.,
RA Teixeira M.M.G., de Camargo E.F.P., de Sousa W., Schenkman S.,
RA de Vasconcelos A.T.R.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated
CC doublet microtubules (DMTs) in cilia axoneme, which is required for
CC motile cilia beating. {ECO:0000256|ARBA:ARBA00035003}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC {ECO:0000256|ARBA:ARBA00004430}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPY34696.1}.
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DR EMBL; ATMH01001406; EPY34696.1; -; Genomic_DNA.
DR EMBL; ATMH01000515; EPY36570.1; -; Genomic_DNA.
DR AlphaFoldDB; S9W654; -.
DR EnsemblProtists; EPY34696; EPY34696; STCU_01406.
DR EnsemblProtists; EPY36570; EPY36570; STCU_00515.
DR OrthoDB; 160134at2759; -.
DR Proteomes; UP000015354; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR Gene3D; 2.30.29.170; -; 3.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR006602; DM10_dom.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR040193; EFHC1/EFHC2/EFHB.
DR PANTHER; PTHR12086; EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12086:SF11; EF-HAND DOMAIN-CONTAINING FAMILY MEMBER C2; 1.
DR Pfam; PF06565; DM10_dom; 3.
DR SMART; SM00676; DM10; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS51336; DM10; 3.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000015354}.
FT DOMAIN 83..187
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT DOMAIN 243..365
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT DOMAIN 413..512
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
SQ SEQUENCE 748 AA; 84781 MW; A0E34BDDEB4BB022 CRC64;
MAFNESQQMK KDFRLPMVPG STCGEELMRR NYHKSHVVGS RPDCATTYGS VPQDQTLKPA
DTMQAAGSTR APGLSKEDCA LLAGKVLRFF AYTIETVPES SVEKERVRKV FIQYFLEDNT
MSVTEPKEDN SGIAFRANLK RHIVPAPDGT PITFQNFQVG EPITFYGNTY MVYDADAFTR
DFMCSIGQEL APAFDVPDDL YTTMRNQPAA RAHDVQSLAA GTNLDIMLTP DQVRATQQFL
ANDRKVLRCD CTWDDSVSLH GYKHFLTLYY FLSDGSLALV EKETQNSGRD PFPRFFSRQK
IARPTDPNGK FDSSTLGSVT FKENKNTDYY SDKDIRIGKV LDLYGRKVKI HGYNQFTKDY
LEKTFGITDH TVIPGAVPPP FVPPGTVRRE ATDGEVLERH QKKQLDLRKH KFATAAVKFL
MRLDNDLFAD CIRRFVLAFY PADNSIAIFE PVIRNSGIVG GKFLQRQQVR APSGEYFTSN
DFYVGAKVVI NKYAFVVLKT DEHSLNYMES NADEFSHSDI NRIVRKMQAM LTSKPSGLAD
AFHAADQESK ELNMETLLGI FERLQLDMPE QELLTVLRYF DHNNESYVSY EEVASRVLPE
GAQVSSDARP WTEIYEQSVR QEQTAFVVDE EQEARKREAV ACTEAAAAGA MTVLELFDQR
RQLFIKELHA IVDYARDSLL GTDEFKRCLR QKLQVSNATL PDDQLNALCG KLFPPAFPRV
SYEELMRLFN GTSTLHHTLK LIAQKKTC
//
