ID S9WFX5_CAMFR Unreviewed; 231 AA.
AC S9WFX5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Keratin, type II cytoskeletal 7 {ECO:0000256|ARBA:ARBA00039431};
DE AltName: Full=Cytokeratin-7 {ECO:0000256|ARBA:ARBA00042963};
DE AltName: Full=Keratin-7 {ECO:0000256|ARBA:ARBA00042887};
DE AltName: Full=Type-II keratin Kb7 {ECO:0000256|ARBA:ARBA00043134};
GN ORFNames=CB1_001913002 {ECO:0000313|EMBL:EPY74674.1};
OS Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX NCBI_TaxID=419612 {ECO:0000313|EMBL:EPY74674.1, ECO:0000313|Proteomes:UP000030684};
RN [1] {ECO:0000313|EMBL:EPY74674.1, ECO:0000313|Proteomes:UP000030684}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=bactrian camel {ECO:0000313|Proteomes:UP000030684};
RX PubMed=23149746;
RG Bactrian Camels Genome Sequencing and Analysis Consortium;
RA Jirimutu, Wang Z., Ding G., Chen G., Sun Y., Sun Z., Zhang H., Wang L.,
RA Hasi S., Zhang Y., Li J., Shi Y., Xu Z., He C., Yu S., Li S., Zhang W.,
RA Batmunkh M., Ts B., Narenbatu, Unierhu, Bat-Ireedui S., Gao H.,
RA Baysgalan B., Li Q., Jia Z., Turigenbayila, Subudenggerile, Narenmanduhu,
RA Wang Z., Wang J., Pan L., Chen Y., Ganerdene Y., Dabxilt, Erdemt, Altansha,
RA Altansukh, Liu T., Cao M., Aruuntsever, Bayart, Hosblig, He F., Zha-ti A.,
RA Zheng G., Qiu F., Sun Z., Zhao L., Zhao W., Liu B., Li C., Chen Y.,
RA Tang X., Guo C., Liu W., Ming L., Temuulen, Cui A., Li Y., Gao J., Li J.,
RA Wurentaodi, Niu S., Sun T., Zhai Z., Zhang M., Chen C., Baldan T.,
RA Bayaer T., Li Y., Meng H.;
RT "Genome sequences of wild and domestic bactrian camels.";
RL Nat. Commun. 3:1202-1202(2012).
CC -!- SUBUNIT: Heterotetramer of two type I and two type II keratins.
CC Interacts with eukaryotic translation initiator factor 3 (eIF3) subunit
CC EIF3S10. Interacts with GPER1. {ECO:0000256|ARBA:ARBA00038822}.
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DR EMBL; KB017992; EPY74674.1; -; Genomic_DNA.
DR AlphaFoldDB; S9WFX5; -.
DR Proteomes; UP000030684; Unassembled WGS sequence.
DR GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR032444; Keratin_2_head.
DR InterPro; IPR003054; Keratin_II.
DR PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45616:SF21; KERATIN, TYPE II CYTOSKELETAL 7; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF16208; Keratin_2_head; 1.
DR PRINTS; PR01276; TYPE2KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754};
KW Keratin {ECO:0000256|ARBA:ARBA00022744};
KW Reference proteome {ECO:0000313|Proteomes:UP000030684}.
FT DOMAIN 89..231
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 86..226
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 231 AA; 26156 MW; 38DD8FE75EFF16B8 CRC64;
MSFHFSSCST ALPGHGTQVP LSSMSPCGFG SSSSSHLYGL GTSQPRVAMC SSYRGPVGAG
IREVTINQSL LTPLQVDIDA SIQQVRQEER EQIKTLNNKL ASFINKVRFL EQRNKLLETT
WALLQEQKST KSSRLPGIFE ARIAGLRKQL ETIQLDRDRL EVELRNMQDI VEDFKNKYED
ESNRRTAAEN EIVVLKKDAD VAYMNKVELE ARVDALNDEI NFLRTLYQEE L
//
