GenomeNet

Database: UniProt
Entry: S9WYQ5_CAMFR
LinkDB: S9WYQ5_CAMFR
Original site: S9WYQ5_CAMFR 
ID   S9WYQ5_CAMFR            Unreviewed;       424 AA.
AC   S9WYQ5;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   31-JUL-2019, entry version 32.
DE   SubName: Full=ATP-sensitive inward rectifier potassium channel 8 {ECO:0000313|EMBL:EPY81258.1};
GN   ORFNames=CB1_000743134 {ECO:0000313|EMBL:EPY81258.1};
OS   Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Tylopoda;
OC   Camelidae; Camelus.
OX   NCBI_TaxID=419612 {ECO:0000313|EMBL:EPY81258.1};
RN   [1] {ECO:0000313|EMBL:EPY81258.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Naran {ECO:0000313|EMBL:EPY81258.1};
RG   The Bactrian Camels Genome Sequencing and Analysis Consortium;
RA   Yao J., Meng H.;
RL   Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EPY81258.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Naran {ECO:0000313|EMBL:EPY81258.1};
RX   PubMed=23149746;
RG   Bactrian Camels Genome Sequencing and Analysis Consortium;
RA   Jirimutu null, Wang Z., Ding G., Chen G., Sun Y., Sun Z., Zhang H.,
RA   Wang L., Hasi S., Zhang Y., Li J., Shi Y., Xu Z., He C., Yu S., Li S.,
RA   Zhang W., Batmunkh M., Ts B., Narenbatu null, Unierhu null,
RA   Bat-Ireedui S., Gao H., Baysgalan B., Li Q., Jia Z.,
RA   Turigenbayila null, Subudenggerile null, Narenmanduhu null, Wang Z.,
RA   Wang J., Pan L., Chen Y., Ganerdene Y., Dabxilt null, Erdemt null,
RA   Altansha null, Altansukh null, Liu T., Cao M., Aruuntsever null,
RA   Bayart null, Hosblig null, He F., Zha-ti A., Zheng G., Qiu F., Sun Z.,
RA   Zhao L., Zhao W., Liu B., Li C., Chen Y., Tang X., Guo C., Liu W.,
RA   Ming L., Temuulen null, Cui A., Li Y., Gao J., Li J., Wurentaodi null,
RA   Niu S., Sun T., Zhai Z., Zhang M., Chen C., Baldan T., Bayaer T.,
RA   Li Y., Meng H.;
RT   "Genome sequences of wild and domestic bactrian camels.";
RL   Nat. Commun. 3:1202-1202(2012).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; KB017008; EPY81258.1; -; Genomic_DNA.
DR   RefSeq; XP_006184593.1; XM_006184531.2.
DR   GeneID; 102511968; -.
DR   KEGG; cfr:102511968; -.
DR   CTD; 3764; -.
DR   KO; K05001; -.
DR   OrthoDB; 956263at2759; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015272; F:ATP-activated inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003278; K_chnl_inward-rec_Kir6.1.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF11; PTHR11767:SF11; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01331; KIR61CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|EMBL:EPY81258.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     73     94       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    154    178       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       37    183       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      191    361       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION      375    424       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    390    424       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   SITE        170    170       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   424 AA;  47955 MW;  973EAA5900C6519C CRC64;
     MLARKSIIPE EYVLARIAAE NLRKPRIRDR LPKARFIAKS GACNLAHKNI REQGRFLQDI
     FTTLVDLKWR HTLVIFTMSF LCSWLLFAIM WWLVAFAHGD IYAYMEKSGM EKSGLESTVC
     VTNVRSFTSA FLFSIEVQVT IGFGGRMMTE ECPLAITVLI LQNIVGLIIN AVMLGCIFMK
     TAQAHRRAET LIFSRHAVIA VRNGKLCFMF RVGDLRKSMI ISASVRIQVV KKTTTPEGEV
     VPIHQLDIPV DNPIESNNIF LVAPLIICHV IDKRSPLYDI SATDLANQDL EVIVILEGVV
     ETTGITTQAR TSYIAEEIQW GHRFVSIVTE EEGVYSVDYS KFGNTVKVAA PRCSARELDE
     KPSILIQTLQ KSELSHQNSL RKRNSMRRNN SMRRNNSIRR NNSSLMVPKV QFMTPEGTQN
     TSES
//
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