ID S9X4Y4_SCHCR Unreviewed; 589 AA.
AC S9X4Y4;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=DNA-directed RNA polymerase III subunit RPC3 {ECO:0000256|RuleBase:RU367076};
DE Short=RNA polymerase III subunit C3 {ECO:0000256|RuleBase:RU367076};
GN ORFNames=SPOG_04804 {ECO:0000313|EMBL:EPY52147.1};
OS Schizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 /
OS NBRC 106824 / NRRL Y48691) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=653667 {ECO:0000313|EMBL:EPY52147.1, ECO:0000313|Proteomes:UP000015464};
RN [1] {ECO:0000313|EMBL:EPY52147.1, ECO:0000313|Proteomes:UP000015464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 / NRRL Y48691
RC {ECO:0000313|Proteomes:UP000015464};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC Specific core component of RNA polymerase III which synthesizes small
CC RNAs, such as 5S rRNA and tRNAs. {ECO:0000256|ARBA:ARBA00025127,
CC ECO:0000256|RuleBase:RU367076}.
CC -!- SUBUNIT: Component of the RNA polymerase III (Pol III) complex
CC consisting of 17 subunits. {ECO:0000256|RuleBase:RU367076}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU367076}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000256|RuleBase:RU367076}.
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DR EMBL; KE546990; EPY52147.1; -; Genomic_DNA.
DR RefSeq; XP_013023530.1; XM_013168076.1.
DR AlphaFoldDB; S9X4Y4; -.
DR STRING; 653667.S9X4Y4; -.
DR EnsemblFungi; EPY52147; EPY52147; SPOG_04804.
DR GeneID; 25039117; -.
DR eggNOG; KOG2587; Eukaryota.
DR HOGENOM; CLU_023294_0_0_1; -.
DR OMA; KHRFVRH; -.
DR OrthoDB; 1429291at2759; -.
DR Proteomes; UP000015464; Unassembled WGS sequence.
DR GO; GO:0005666; C:RNA polymerase III complex; IEA:UniProtKB-UniRule.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 3.
DR InterPro; IPR013197; RNA_pol_III_RPC82-rel_HTH.
DR InterPro; IPR008806; RNA_pol_III_Rpc82_C.
DR InterPro; IPR039748; RPC3.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR12949:SF0; DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3; 1.
DR PANTHER; PTHR12949; RNA POLYMERASE III DNA DIRECTED -RELATED; 1.
DR Pfam; PF08221; HTH_9; 1.
DR Pfam; PF05645; RNA_pol_Rpc82; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU367076}; Nucleus {ECO:0000256|RuleBase:RU367076};
KW Reference proteome {ECO:0000313|Proteomes:UP000015464};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU367076}.
FT DOMAIN 8..67
FT /note="RNA polymerase III subunit RPC82-related helix-turn-
FT helix"
FT /evidence="ECO:0000259|Pfam:PF08221"
FT DOMAIN 145..422
FT /note="RNA polymerase III Rpc82 C -terminal"
FT /evidence="ECO:0000259|Pfam:PF05645"
FT REGION 219..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 589 AA; 68287 MW; AAE0CBFFC462D695 CRC64;
MSQYAVGLCE ILVDEFFGEC CSEIASILLR HGRMNLPMIL KRTNLPGSKI RQALASLMQH
HMVLFVTAIE QLREVTYYEA QWQEMYNLIR KGKDVYLVSQ KLNQESASIA KYVSTQGRAR
VQDVYSAFGK SPDDTDEENR LLQQNITDLI YLKYLVVVQP RHLIPVGDQE MQLRIKYLEQ
RKSENVSEIK KNREVNDSVS LEMAQLRSSD MAENQGLIRK PKDSIPRPTK RKRRNVTTSS
MTGDLNEVLD DENSILLPDP AAHVRVNRAK FSFLARNQRL VHWVERRIGK TAAIIYSHLL
ASLESKFVGS PSPATVLTIT TMELTRNFPK DIDIESCFAK SSNVRKPSAK AAFDQLDEEL
EVEDEEDEDY EENIDDESNS KSKVLAQHLE LLADSSLKFI TRVGNRGMGE WKIDFVYLTN
MLRSVEFENI LDEKLGDRAT RLLRIIKDKG KIEEKQLANI ALLRQKDLRT VLQSMAEMGA
LELQEVPRSS DRAPSKTFYL WFHRSERAYS IFLDHLYEVI ARMFHRLRDE RAQRSQLIDK
AERIDIKGKE EEYLQKFEQV ELKKLRSYEE KLLLQASRLD ELILIFKDD
//
