ID S9X735_SCHCR Unreviewed; 402 AA.
AC S9X735;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE SubName: Full=G-protein alpha subunit {ECO:0000313|EMBL:EPY52887.1};
GN ORFNames=SPOG_02206 {ECO:0000313|EMBL:EPY52887.1};
OS Schizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 /
OS NBRC 106824 / NRRL Y48691) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=653667 {ECO:0000313|EMBL:EPY52887.1, ECO:0000313|Proteomes:UP000015464};
RN [1] {ECO:0000313|EMBL:EPY52887.1, ECO:0000313|Proteomes:UP000015464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 / NRRL Y48691
RC {ECO:0000313|Proteomes:UP000015464};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
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DR EMBL; KE546989; EPY52887.1; -; Genomic_DNA.
DR RefSeq; XP_013022765.1; XM_013167311.1.
DR AlphaFoldDB; S9X735; -.
DR STRING; 653667.S9X735; -.
DR EnsemblFungi; EPY52887; EPY52887; SPOG_02206.
DR GeneID; 25036530; -.
DR eggNOG; KOG0082; Eukaryota.
DR HOGENOM; CLU_014184_6_0_1; -.
DR OMA; CCVSAED; -.
DR OrthoDB; 2897309at2759; -.
DR Proteomes; UP000015464; Unassembled WGS sequence.
DR GO; GO:0090726; C:cortical dynamic polarity patch; IEA:EnsemblFungi.
DR GO; GO:0005834; C:heterotrimeric G-protein complex; IEA:InterPro.
DR GO; GO:0001664; F:G protein-coupled receptor binding; IEA:InterPro.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:EnsemblFungi.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0043409; P:negative regulation of MAPK cascade; IEA:EnsemblFungi.
DR GO; GO:0071507; P:pheromone response MAPK cascade; IEA:EnsemblFungi.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002975; Fungi_Gprotein_alpha.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF242; GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR PRINTS; PR01241; GPROTEINAFNG.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000015464};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 402 AA; 46067 MW; AE9FAB6D4019F829 CRC64;
MGCMSSKYTD SSGGEVSKKK LVKLENPGRV SSPESERNTV KEHWLNIVLR GKPQNSNAAV
SNANGNGNEI KVLLLGAGDS GKTTIMKQMR LLYSPGFNQA ARRQYRIMIF ENIITSVCLL
LEAMENSGMS LLPENEKYRP IILRKHTIQL NEPFPADLYE ALRALTLDPK IRAAQNCGSN
LSLLDNFYYY QDHIDRIFDP QYLPSDQDIL HCRIKTTGIS EETFLLNRHR YRFFDVGGQR
SERRKWIHCF ESVTALLFLV SLAGYDQCLV EDNSGNQMQE ALLLWDSICN SSWFAESAMI
LFLNKLDLFK RKVHISPIQQ YFPDYQETPT TPTFVQTQCP FSDNAVRSGM YYFYLKFESL
NRIASRSCYC HFTTATDTSL LQRVMVSVQD TIMSNNLQSL MF
//
