ID   S9X924_CAMFR            Unreviewed;      1079 AA.
AC   S9X924;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=Histone deacetylase 10 {ECO:0000313|EMBL:EPY84858.1};
GN   ORFNames=CB1_000437009 {ECO:0000313|EMBL:EPY84858.1};
OS   Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX   NCBI_TaxID=419612 {ECO:0000313|EMBL:EPY84858.1, ECO:0000313|Proteomes:UP000030684};
RN   [1] {ECO:0000313|EMBL:EPY84858.1, ECO:0000313|Proteomes:UP000030684}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=bactrian camel {ECO:0000313|Proteomes:UP000030684};
RX   PubMed=23149746;
RG   Bactrian Camels Genome Sequencing and Analysis Consortium;
RA   Jirimutu, Wang Z., Ding G., Chen G., Sun Y., Sun Z., Zhang H., Wang L.,
RA   Hasi S., Zhang Y., Li J., Shi Y., Xu Z., He C., Yu S., Li S., Zhang W.,
RA   Batmunkh M., Ts B., Narenbatu, Unierhu, Bat-Ireedui S., Gao H.,
RA   Baysgalan B., Li Q., Jia Z., Turigenbayila, Subudenggerile, Narenmanduhu,
RA   Wang Z., Wang J., Pan L., Chen Y., Ganerdene Y., Dabxilt, Erdemt, Altansha,
RA   Altansukh, Liu T., Cao M., Aruuntsever, Bayart, Hosblig, He F., Zha-ti A.,
RA   Zheng G., Qiu F., Sun Z., Zhao L., Zhao W., Liu B., Li C., Chen Y.,
RA   Tang X., Guo C., Liu W., Ming L., Temuulen, Cui A., Li Y., Gao J., Li J.,
RA   Wurentaodi, Niu S., Sun T., Zhai Z., Zhang M., Chen C., Baldan T.,
RA   Bayaer T., Li Y., Meng H.;
RT   "Genome sequences of wild and domestic bactrian camels.";
RL   Nat. Commun. 3:1202-1202(2012).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; KB016723; EPY84858.1; -; Genomic_DNA.
DR   AlphaFoldDB; S9X924; -.
DR   Proteomes; UP000030684; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004707; F:MAP kinase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 2.
DR   InterPro; IPR000286; His_deacetylse.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR003527; MAP_kinase_CS.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR   PANTHER; PTHR10625:SF18; POLYAMINE DEACETYLASE HDAC10; 1.
DR   Pfam; PF00850; Hist_deacetyl; 1.
DR   Pfam; PF00069; Pkinase; 2.
DR   PRINTS; PR01270; HDASUPER.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF52768; Arginase/deacetylase; 2.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS01351; MAPK; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000030684}.
FT   DOMAIN          1..342
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
SQ   SEQUENCE   1079 AA;  117706 MW;  9C43BA4EB5D998BF CRC64;
     MKLYRPFQSE LFAKRAYREL RLLKHMRHEN VIGLLDVFTP DETLDAFTDF YLVMPFMGTD
     LGKLMKHEKL SEDRIQFLAY QMLKGLKYIH DAGIIHRDLK PGNLAVNEDC ELKAWKAAGP
     GPGPGRGTRP QPSGQWLSSL WALGRHLMGM AWATLPDLLE VKGEKCAWFP RPEPGRAEVA
     SPQILDFGLA RQADSEMTGY VVTRWYRAPE VILNWMHYTQ TVDIWSVGCI MAEMITGKTL
     FKGNDREPCS LAPPCTPDLG KDLDQLKEIM KVTGTPPAEF VQRLQSDEAK NYMKGLPELE
     KKDFASILTN ASPLAVNLLE KMLVLDAERR VTAAEALAHP YFEALQDTED EPKAQKYDES
     FDDVDRTLDE WKRHKAGAHL SSILCHDHGQ AMGTALVYHE DMTAARLLWE DPECEIECPQ
     RLTAALEGLQ QRGLEQRCLR LVAREASEAE LGLVHSPEYV ALLRGTQALG TQELQALSGQ
     YDAVYFHPRT FHCARLAVGA ALQLVDAVMT GAVRNGLALV RPPGHHSQRA AANGFCVFNS
     VAIAARHAKQ KHGLHRVLIV DWDVHHGQGT QYIFEDDPSV LYFSWHRYEH RRFWPYLRES
     DADAVGQGQG LGFTVNLPWN QVGMGNADYM AAFLHVLLPL AFERGTEPLG FDPELVLVSA
     GFDSAIGDPE GQMQATPECF AHLTQLLQVL ADGRVCAVLE GGYHLESLSQ SVCMMVQALL
     GDPAPPLSGP MVPHGSALES IQSVRAAQAP YWMSLQQQGA APVLSPSTCS PEGKPSPLLP
     WGPEFKAAAT QTMAALSSLL DKLCLNPTPP VRTAVALTAP DAALVLPPGV LCQERSALPE
     EMQAWARPHK ALAQDKALTA LGKVLYLLDR LLDGQVSSGI AATPAPATAA TLDVAIRCGL
     SHGAQRLLCV AVGQLDRPPD LTDDGRNLWL NIGGKEAAAP STFHVCVPLP GTTGGFLNCV
     LALVLPLAYS FQPDLVLVAL GPAHGLRDPQ AALLTALLRG PAGGRVLALI DEESTPQLVG
     VLARVLHGEA PPSLGPFSMA SPEDMQALMR LRGPLEPQWK MLQVAGEAGV GVVRLRVSA
//